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Type 4: Over-Forcused Anxiety and Depression


These people have trouble shifting attention and tend to get locked into negative thoughts or behaviors. When this is combined with excessive basal ganglia activity, people get stuck on anxious thoughts. When it is combined with excessive deep limbic activity, people get stuck on negative, depressing thoughts.

Many people get “stuck” on both anxiety-provoking and depressive thoughts: obsessive-compulsive disorder (stuck on negative thoughts or actions); phobias (stuck on a fear); eating disorders (stuck on negative eating behavior); and Post-Traumatic Stress Disorder (PTSD, stuck on a past traumatic event) fit into this type. This type is also associated with people who worry, tend to hold grudges, and have oppositional or argumentative behavior. This type of anxiety and depression tends to occur more frequently in children or grandchildren of alcoholics.


  • Increased anterior cingulate gyrus activity
  • Increased basal ganglia and/or deep limbic activity at rest and while the person is concentrating