Prefrontal Cortex (PFC)

Top down surface view Left side surface view Underside surface view
PFC Functions	PFC Problems	Some Conditions Affecting the PFC
PFC Dorsal lateral Attention Planning   Follow through	Inattention Lack of forethought Procrastination	ADHD Brain Trauma Schizophrenia Antisocial Personality Conduct disorders	Depression Dementia Borderline Personality
PFC Inferior orbital Impulse control Inhibition Judgment Empathy Ethics Morality	Impulsive Disinhibited Poor judgment Lack of empathy Lack of ethics	PFC Treatments Supplement L-tyrosine Organizational help Relationship counseling Higher protein diet	Coaching Intense aerobic exercise Stimulating activities Neurofeedback
		PFC Meds Stimulants Adderall (mixture of amphetamine salts) Dexedrine (dextroamphetamine) Ritalin/Concerta (methylphenidate) Non-Stimulants: Strattera, Provigil

Decreased perfusion in the PFC during a concentration task is often associated with impulsivity, short attention span, distractibility and difficulties with organization and planning. We have seen a strong correlation between this finding and ADHD and ADD, especially when this occurs during the performance of a concentration task. When decreased activity in the PFC is seen during a resting state, it is often associated with depressive disorders, and may be responsive to antidepressant medication. When it is seen in both the resting and concentration states there may be a combination of depression and ADD or ADHD present. Clinical correlation is always needed. This pattern has also been seen in response to head injuries affecting this part of the brain, and later in life in some dementia processes.