Amen Clinics Home
Call Today!
(888) 564-2700

Monthly Archives: July 2008

High Blood Pressure, Low Brain Function — Treat Hypertension to Have a Great Brain

Here is a fascinating research study from Russia on the importance of taking care of your blood pressure. High blood pressure decreases blood flow to your brain and impairs concentration and other cognitive processes. Lose weight, exercise and get hypertension treated!!

“The aim of our study was to estimate brain perfusion and cognitive function (CF) in patients with arterial hypertension (AH) before and after hypotensive therapy. The study included 15 patients (mean age, 53.0+/-5.7 years) with previously untreated or ineffectively treated essential hypertension of the second degree.

All patients underwent brain single photon emission computed tomography (SPECT) scanning with 99mTc-hexamethylpropylene amine oxime (99mTc-HMPAO) and comprehensive neuropsychological testing before and after 24 weeks of hypotensive therapy (angiotensin-converting enzyme [ACE] inhibitor or diuretics).  The brain perfusion was significantly lower (15-22%) in all regions of AH patients. These patients showed a 25% decrease in attention and psychomotor speed as well as a 14% decrease in mentation. Six months of hypotensive therapy led to an increase in brain perfusion by an average of 7-11% in all brain regions. After treatment these patients demonstrated an average 11-18% improvements in attention and psychomotor speed, as well as an average 10% improvement in abstract mentation.

Marked signs of brain hypoperfusion and impaired CF: decrease in attention, slowing psychomotor speed and mentation was found in hypertensive patients even without focal neurological symptomatology. Twenty-four weeks of hypotensive treatment with ACE inhibitors or diuretics had a positive effect on cerebral perfusion and led to CF improvement.

Reference: Efimova IY, Efimova NY, Triss SV, Lishmanov YB. Department of Nuclear Medicine, Institute of Cardiology, Tomsk Research Center, Tomsk, Russia. nuclear@cardio.tsu.ru. Brain perfusion and cognitive function changes in hypertensive patients. Hypertens Res. 2008 Apr;31(4):673-8.

Another Reason To Love Blueberries

Blueberries help protect the brain, but the fruit may also have a heart protective effect by significantly lowering cholesterol, Canadian researchers say.Lead scientist Wilhelmina Kalt of Agriculture and Agri-Food Canada conducted tests on pigs fed a blueberry-supplemented diet. Blueberry-supplemented diets resulted in a reduction in total cholesterol including both low-density lipoprotein, or LDL the bad cholesterol and high-density lipoproteins, or HDL, the good cholesterol, Kalt said.

In feeding trials, we found that blueberry supplementation reduced plasma cholesterol levels more effectively when the animals received a mostly plant-based diet than when they received a less heart-healthy diet, Kalt said in a statement. The soy, oats and barley contained in these diets may have functioned synergistically with the blueberries to beneficially affect plasma lipids.

The study, published in the British Journal of Nutrition, found that the greatest reduction in total, LDL and HDL cholesterol levels was found in pigs fed a 2 percent blueberry diet equivalent to approximately 2 one-cup servings of blueberries in the human diet.

Pigs have levels of LDL similar to humans and are susceptible to diet-induced vascular disease, develop atherosclerotic plaques in the aorta and carotid artery and have a similar blood pressure and heart rate as humans, Kalt said.