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Monthly Archives: September 2008

A Magnificent Mind Can Be Yours/Part 1 of 6

My new book Magnificent Mind At Any Age is coming out 12/2/09.  You can pre-order it on the website here.  Here is Part One of Six of what you can expect in the book. 

Protect Your Amazing, But Fragile Brain

The brain is the most complicated organ in the universe.  It is estimated that the brain has 100 billion nerve cells and more connections in it than there are stars in the universe.  Even though the brain is only about 2% of your body’s weight, it uses about 25% of the calories you consume.  If you take a piece of brain tissue the size of a grain of sand, it contains 100,000 neurons and a billion connections all talking to one another.  If you are not thoughtful, the brain loses an average of 85,000 brain cells a day, or one per second.  Information in the brain travels at the speed of 268 miles per hour, unless of course you are drunk, which really slows things down.  The brain is the organ of loving, learning, behaving, intelligence, personality, character, belief and knowing.

The brain is also very soft and it is housed in a really hard skull.  Most people think of the brain as firm, fixed, and rubbery.  Yet, that is not how it is inside your skull.  That is how it is once it is fixed in formaldehyde on the pathologist’s table.  Inside your skull the brain is 80% water and the consistency of soft butter, custard, somewhere between egg whites and jello.  Neurosurgeon, Katrina Firlik, in her book Another Day In The Frontal Lobe, describes the brain “like tofu, the soft kind, which when caught in suction during surgery slurps into the tube.” 

Your soft “tofu-like” brain is housed in a really heard skull that has many ridges.  These ridges damage the brain during trauma.  If this is true, which it is, then why would you ever let a child hit a soccer ball with their heads, play tackle football (even with helmets), skateboard, snowboard or ski without helmets?  Why would you ever buy your teenager his first motorcycle or take her four wheeling in the desert unless you didn’t like them?  From a neuroscientists point of view, these are dangerous activities that could grievously injure the brain.  Sports like boxing, football, motocross and cage fighting are simply not worth the risk.  The brain loves physical activity and it is better to think about safer brain sports such as tennis, table tennis, track and field (although not pole vaulting) and basketball.   

A 2007 study by John Adams and colleagues at the University of Cincinnati College of Medicine found that playing soccer, where the ball is often hit with the head, may be linked to long-term brain injury and memory problems later in life.  Researchers found evidence of reduced gray matter in the brains of male college soccer players, compared with young men who had never played. 

The single most important thing I have learned from looking at tens of thousands of scans is that mild traumatic brain injuries change people’s whole lives (by damaging their brain) and no one knows it.  The brain injured person often subsequent to the injury suffers from emotional, behavioral or cognitive problems that may lead them to a psychiatrist or psychologist, who typically never looks at the brain.  Problems which are physically based are often considered psychological.  If you never look at the brain, you miss what many researchers have called the “silent epidemic.”  There are two million reported new brain injury cases every year, and millions of others that go unnoticed. 

When I first started the imaging work, I saw a lot of brain injury patterns on scans.  When I asked patients about a history of head injuries they denied them.  When I pressed, a whole new world opened up.  I found out that people often forgot significant injuries. I had to ask them three, four, even ten times.  Many people forget or they did not realize that they have had a serious brain injury.  You would be amazed at how many people, after repeatedly saying no to this question, suddenly get an ‘ah ha’ look on their face and say, “Why yes, I fell out of a second story window at age seven.”  Or, they tell us they went through the windshield of a car head first, had concussions playing football or soccer or fell down a flight of stairs.  Not all brain injuries, even serious ones, will cause damage.  There is an interaction between genetic vulnerability and trauma.  Plus, the brain is buffered by the cerebral spinal fluid that bathes it.  Still, damage can occur more than most know.

So many of the troubled people we see at the Amen Clinics have had a brain injury or two or three.  Damaging your brain may limit or impair your ability to be successful in any area of your life.  People who have experienced head injuries have a higher incidence of drug abuse, alcoholism, mood problems, divorce, domestic violence, arrests, financial problems and every other type of trouble that leads to failure.  Be smart. If you want to be your best, protect your soft brain.

Vitamin D Deficiency Link to MS

For many years it has been known that MS is increased in more northern latitudes.  In a new study a link was found between vitamin D deficinencies and MS. More northern latitudes have less sun exposure and less vitamin D.  This is an important study that leads to important suggestion of intervention.  See the study from Medscape below.

September 26, 2008 (Salt Lake City, Utah) — Results from a new study unite the genetic and environmental risks of multiple sclerosis in a disease-specific and gene-environment interaction. Presenting at the American Neurological Association 133rd Annual Meeting, researchers described a link between vitamin D and the pathogenesis of MS.

“There’s a connection between the 2 — no question about it,” lead investigator George Ebers, MD, from the University of Oxford, in the United Kingdom, told Medscape Neurology & Neurosurgery. “But exactly how it works is not clear yet.” Asked to comment on the work, Emmanuelle Waubant, MD, from the University of California, San Francisco said, “MS is a very heterogeneous disease, and this is an interesting way to look at the factors that predispose people.” She noted, “This study looks at the bigger picture and is the way things should be done. The data provide decent traction and it is an interesting result.” 

Dr. Ebers and his team examined the major histocompatibility complex (MHC) for deoxyribonucleic acid (DNA) sequences predicted to respond to vitamin-D complexes. They identified a single sequence, which appeared to be functionally active because it transfected the segment into cell lines and measured functional expression in response to added vitamin D. Unexpectedly, they found this sequence is haplotype-specific and perhaps evolving in response to selective pressures characterizing the northern migration of European populations. This solitary MHC vitamin-D–responsive element is strategically located in the promoter region of the class II complex specific to a haplotype associated with MS risk,

Dr. Ebers told the meeting.  “These findings further implicate vitamin D in environmentally mediated MS risk,” he said. 

Sequence Haplotype-Specific During an interview after the session, Dr. Ebers said his group was surprised by what it found. “Most times you don’t find exactly what you are looking for, but in this case, that is exactly what we found. It was as plain as day.” The data suggesting vitamin D is deficient in MS are strong, Dr. Waubant added. “What is unclear is whether or not it also affects the severity of disease.” 

“Everyone who has examined this from the National Academy of Sciences to the dietary committee of the European Union to a variety of professional organizations all agree pretty much that the amount of vitamin D that people are getting is too low,” Dr. Ebers pointed out.“I know all the experts in the field, and they’ve sort of voted with their feet,” he said. “They’re all on vitamin D and their family is on it too. As far as anyone can tell, the amounts in question are harmless, and it’s dirt cheap.” Some experts are advocating that given the potential benefit, vitamin D should be widely administered. But others have reservations and are recommending a more cautious approach. “I’m reluctant to say there’s absolutely no risk, because people have been wrong on these things,” Dr. Ebers told Medscape Neurology & Neurosurgery. “But I think in this particular case, the evidence has been so strong that it’s safe, and all the experts who examine this are comfortable. Plus, many are giving 2000 units a day to pregnant women, so that should be as reassuring as anything.”

A Magnificent Mind Can Be Yours

It has been a while since I have written.  Forgive my absence.  I just finished filming a new PBS special based on my new book, Magnificent Mind At Any Age, that is coming out December 2nd.  Over the next few months I will include snippets of the book and PBS show in the blog.  Here is a piece from Chapter 2: A Magnificent Mind Starts With A Healthy Brain. 

“Brains run the world.  They run the stock market and the local market.  They run huge corporations and the “mom and pop shop” down the street.  Brains run churches, banks, hotels, tennis clubs, dry cleaners, professional basketball teams, Internet dating services and universities.  Brains run marriages, choirs, homeowner associations and terrorist groups.  Your brain runs you and is significantly involved in running your family.   

Yet, even though the brain is involved with everything we do at work and at home, we rarely think about or honor the brain.  There is no formal education about the brain in MBA programs; no brain training programs at church; no brain exercises in customer service or management programs; and no real practical education about the brain in school.  The lack of brain education is a huge mistake, because success in all we do starts with a healthy brain.  The characteristics of a magnificent mind include personal responsibility, clear goals, good attention, consistent effort, effective social skills, impulse control, motivation, integrity and creativity.  Yet, few people realize that all of these are brain functions.  A healthy brain makes these characteristics easier to incorporate in your life, while a damaged or struggling brain makes these much harder.   

Taking great care of your brain is essential to a magnificent mind.  Here is an example. In one of the graduate psychology courses I taught I asked for volunteers for our healthy brain study.  By the year 2000, we had amassed tens of thousands of SPECT scans for clinical reasons, such as ADHD, anxiety, depression, autism, Alzheimer’s disease, brain trauma, marital strife and violence.  In order to further our research efforts we needed to build a large normal database to compare our clinical studies.  I solicited normal people wherever I went.  Surprisingly, they were not that easy to find.  Christy, one of my favorite students, came up after class very excited.  She said, “You have to scan my 82 year old grandmother, Anna.  She is one of the most normal people I know. You will love her.”  On Christy’s advice and her grandmother’s agreement, we screened Anna and indeed found her to be healthy.  She met all of the criteria for the study: no psychiatric illness at any point in her life, no substance abuse, brain injuries, first degree relatives with psychiatric illness and she was not on any medications.  Anna had been married for 58 years and was a loving wife, mother and grandmother.  She had a sharp, curious mind and was active in her church and community.  She had solid relationships that spanned many years.  Anna never drank alcohol, never smoked and tried to eat healthy.  Anna has one of the healthiest brains I had ever seen, out of nearly 50,000!  Her brain fit her life.   

The First Steps to a Healthier Brain  

Most of us are never taught about how important the brain is, so we go through life thinking about everything but this critically important organ (weight, skin care, finances, children, internet dating, vacations, careers, sports).  I live in Newport Beach, CA, the heart of the OC (Orange County).  We have often been called the plastic society because we have more plastic walking around our streets and beaches than almost any other place in the world.  I often say that we care more about our faces, our boobs, our bellies and our butts, than we do our brain.  How stupid is that?  When you really want to change, the first place to always start is with your brain.  Over the next few days I will give you the first six things you should do to improve your brain health.  Stay tuned.” 

You can preorder Magnificent Mind At Any Age on our website or a www.amazon.com.  Here is the Table of Contents.

Part One: A Magnificent Mind Starts With A Healthy Brain 

Chapter 1. Are You Wired for Success or Failure?  The Secret Behind Why Some People Achieve Their Dreams and Others Don’t 

Chapter 2. A Magnificent Mind Starts with a Healthy Brain: Essential Strategies 

Chapter 3. Encourage Brain Envy: Eliminate the Daily Habits That Hold You Back 

Chapter 4. Hidden Short Circuits May Be Ruining Your Life: Learn How to Identify and Correct Your Vulnerable Areas 

Chapter 5. If Your Were My Family How Would I Treat You? The Four Circles of Health and Healing and Why You  Should Consider Natural Treatments 

Chapter 6. Natural Ways to Heal Attention Deficit Disorder 

Chapter 7. Natural Ways to Heal Anxiety and Depression 

Chapter 8. Natural Ways to Heal Memory Problems and Insomnia 

Part Two: A Magnificent Mind Makes Your Dreams A Reality 

Chapter 9. Ignite Your Passion: Light Up the Brain Circuits that Drive Success 

Chapter 10. Make Your Own Miracles: Use Your Brain to Define Your Dreams and Make Them a Reality 

Chapter 11. Know When to Apply the Brakes: Strengthen Your Brain’s Internal Controls 

Chapter 12. Embrace the Truth: Liberate Yourself from the Lies Polluting Your Brain 

Chapter 13. Get Unstuck: Enhance Your Brain’s Ability to Change and Adapt 

Chapter 14. Develop Mental Toughness: Cultivate a Resilient Brain 

Chapter 15. Enhance Your Social Networks: Build a Brain Trust  

Chapter 16. Be a Maverick Thinker: Stop Anxiety from Allowing Others to Run Your Life 

Chapter 17. Create Lasting Trust: Send the Signals that Build Integrity 

Appendix A: When More Help Is Needed

Appendix B: Why SPECT: What Brain SPECT Imaging Can Tell Clinicians and Patients 

References and Further Reading