Blog-Is Ketamine the Answer for Depression

Is Ketamine the Answer for Depression?

Perhaps you’ve heard of the mental health drug, Ketamine. Ketamine is a cutting-edge treatment for severe depression and suicide. Two-thirds of participants in clinical studies who did not respond to traditional antidepressants experienced fast and lasting resolution of their depressive symptoms after being given ketamine intravenously.The effects of ketamine typically lasted about a week — much longer than would be expected with ketamine’s six-hour half-life in the body.

Ketamine is the safest, most widely used anesthetic in the world. It has dramatic beneficial effects on patients with depression, PTSD, anxiety, and bipolar disorder. Ketamine can decrease and even eliminate suicidal thinking within hours of the infusion.

Ketamine produces a dissociative state, which gives patients a window of clarity that can help them find freedom from dark thoughts and emotional pain. This objective view of their life allows patients to seek help and respond to traditional therapy and counseling. Unlike other medications and therapies, which can take months or even years to produce results, the effects of Ketamine are immediate. 71% of patients report a decrease in depressive symptoms within 24 hours of a Ketamine infusion.

Ketamine injection therapy is a better way to help individuals who have tried everything to alleviate the debilitating effects of depression. If you or someone you know is seeking relief from depression, Ketamine might be an appropriate treatment option. Not all services are offered at each Amen Clinics location. Call us today at 888-288-9834 or reach out online for availability at a clinic near you.

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  1. Kim says:

    I have an on going issues with depression and anxiety and medication have little or no effect. I am very interested in these ideas mentioned in these articles. How do I find a doctor to help facilitate my access to them?

  2. Pat King says:

    how much?

  3. Gloria Porter says:

    Inducing a disassociative state as a treatment for depression? Seriously laughable. Anyone who understands disassociation and what it actually feels like would understand the confusion involved. You don’t magically find clarity when you disassociate, quite the opposite is true.

    Anytime the precise mechanism of action remains a mystery, it’s time to hold off treatment until longitudinal studies are complete. What we do know now is that “ketamine also has direct effects on the delta opioid receptor, and acts to augment opioid mu-receptor function. Ketamine certainly modifies responsiveness to opioid receptors.” So if you would like to dull your depression by putting yourself into a disassociative state and develop the host of problems associated with a blockade of NMDA and HCN1 receptors, which also act upon cholinergic (parasympathetic nervous system), aminergic (serotonin, dopamine and norepinephrine), and opioid systems” . . . that’s your choice.

    Just understand there are a LOT of things which destroy neurotransmitter receptors. Just because a person with treatment resistant depression has burnt out the serotonin receptors using SNRIs/SNRIs, or MAOIs doesn’t mean that initially when they respond on a Beck Inventory with an improved depression score it will magically stay that way on the same dose for the next 6-24 months. Like all psychoactive substances , they will gradually damage the receptors involved. Then the person will have unintended neurologic consequences which in this case would include chronic pain, parasympathetic nervous system malfunction AND the host of problems associated with damage to the serotonin, dopamine and norepinephrine. The only difference with ketamine is that because it spreads the damage more thinly, it will simply take longer to realize just how bad this option really is. Slow uncalculated destruction much like the gradual erosion under a Los Angeles freeway which suddenly opens into a sinkhole. But by that time, the 6-week studies demonstrating improvements will have long since been published and everyone will just shake their heads in disbelief when a Ketamine survivor talks about akathisia, sleep disorders, acquired sensory processing disorder and the host of problems associated with damaged neurotransmitter receptors.

    I expect better from the Amen Clinic.

    • susan white says:

      My daughter age 34 is considering this as a treatment for TRi GEMINAL NEURALGA. SHe has tried all the oral medications available and now gets a lidocaine infusion weekly which lowers the pain but hasn’t cured the condition. What do you think?

      • Mike says:

        Sorry that the educated mind thinks so narrow . Everything we eat , breath , and are exposed to on a daily bases is not good for us either . The facts are that not all of us are the same and what works for me probably won’t work for .

    • Luke says:

      Tons of spurious claims with no evidence to back it up. Your comments are laughable

  4. Danielly says:

    Ketamine doesn’t work that way, silly Gloria. It doesn’t create a blockade. It basically hoses the brain with blood so that the stagnant areas get a chance to exchange synapses which probably haven’t happened in a long time since depression sucks the life out of some whole districts in there. Geez. Ofcourse it works. Thank Goddess.

    • Spider says:

      So her quote of a pharmacology book on the molecular action of ketamine is wrong, but your oh-so-technical description of “hosing with blood” is accurate. Whoo, boy.

  5. Natasha Millikan says:

    I agree with Gloria that the last thing I need is to be in a disassociative state more of the time. That is what the mind does to avoid or hide from trauma.

    Perhaps the disassociative state is temporary during a short window following treatment? It does kinda mean I am likely to get lost on the way home! Or perhaps the word is used for more than one thing? I can imagine there might be a use or uses of the word that are not what some of us already experience.

    Another possibility is that the kind of depression Amen is used to seeing is more physical-trauma induced rather than experiential-trauma induced. Maybe when disassociation is not caused by the mind shying away from pain, it is pleasant to those who experience it?

    I also don’t know why they have these comment sections, since most comments are questions that never get answered. Last time I got contacted by someone on Facebook about some sort of nutritional supplement, but that may have been another reader, as most names are not as unique to find on Facebook.


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