COVID Depression: What Does Sense of Smell Have to Do with Moods?
In August, former First Lady Michelle Obama revealed on her podcast that “I am dealing with some form of low-grade depression.” She’s not the only one. Pandemic-related depression is sweeping across the nation and around the world. A survey in JAMA Network Open found that the rate of depression symptoms in the U.S. increased more than 3-fold during the COVID-19 pandemic, jumping from 8.5% before the pandemic to nearly 28%.
But depression has also been linked to having COVID-19. A 2020 study in the Journal of Alzheimer’s Disease shows that one of the consequences of COVID-19 includes depression, in addition to anxiety, attention problems, obsessive compulsive disorder, memory loss, and more. Another 2020 study appearing in the journal Laryngoscope found that in people with COVID, experiencing a loss of smell and taste was associated with depressed mood and anxiety.
New research shows that up to 80% of people with COVID report experiencing anosmia, or the loss of smell. Surprisingly, depression and anxiety were more likely to be found in people with olfactory dysfunction than in those with other symptoms, such as shortness of breath, fever, or cough.
THE SCIENCE OF SMELL AND MOOD
A wealth of scientific research has shown that our sense of smell and our moods are intertwined. For example:- When scientists chemically blunted the sense of smell in mice for a 2018 study, it induced depressive behavior in the rodents.
- In another study on elderly Koreans, an impaired olfactory function was associated with a significantly higher degree of depression in addition to lower cognitive performance and decreased quality of life.
- A 2016 review of the existing research on anosmia and depression showed that the relationship appears to be a 2-way street. People with depression are more likely to have problems with a sense of smell than healthy controls, and people with anosmia are more likely to have symptoms of depression. And the greater the loss of smell the more severe the depressive symptoms.



