Is it Mental Illness or Mold Toxicity?
By Mark Filidei, D.O.
One of my chief tasks as the Director of Integrative/Functional Medicine at Amen Clinics is to work up what we call a “toxic brain” as seen on brain SPECT imaging. Amen Clinics currently has the world’s largest database of brain SPECT scans—over 160,000 scans from patients in over 150 countries—and it affords us a unique view into the functions of the brain. When working up a toxic, or “encephalopathic,” SPECT scan finding, many etiologies need to be considered, including toxins, infections, allergies, medications, and head trauma. Near the top of my list of possible culprits of abnormal SPECT scans are infections and toxins, especially Lyme disease and toxic mold exposure.
Near the top of my list of possible culprits of abnormal SPECT scans are infections and toxins, especially Lyme disease and toxic mold exposure. —Mark Filidei, DO, Amen Clinics Director of Integrative/Functional Medicine
Mold Could Thrive in Your Home
It is estimated that half of the buildings in the United States may be “WDB”, meaning water-damaged buildings. Construction techniques in the U.S. turn out to be a feast and buffet for mold and fungal organisms. Our homes here are often built of wood and drywall rather than stone or brick as in Europe. Mold and fungi thrive on drywall, wood, and other soft materials. Mold thrives in dark and moist environments and doesn’t take much water to get the process going. A small drip from a leaky toilet, shower, or sink is all it takes. Small roof leaks are also common causes. If you see a stain on the ceiling or the wall there is very likely an associated hidden mold growth. This is not the type of mold that you see on the shower wall, but rather it is lurking behind the walls and in air ducts, crawl spaces, attics, and other areas.Mold Exposure Symptoms
The toxin-producing “black mold” Stachybotrys, as well as other neurotoxic molds, including Aspergillus, Chaetonium, and Wallemia, can have a dramatic effect on the brain and behavior. There are 2 main effects of mold exposure: the physical airway irritating effects like allergies, cough, and fatigue, and the more concerning effects on the central nervous system (CNS) and the brain. Mental and cognitive health symptoms can include:- Brain fog
- Inability to concentrate
- Depression
- Anxiety
- Sleep disorders
- Irritability
- Headache
- Confusion




