ARCHIVE

If you’ve witnessed a parent, grandparent, relative, or friend suffer from the ravages of dementia, you know that it is a condition you wouldn’t wish on anyone. It is devastating and heartbreaking to see previously vibrant, energetic, and smart people you care about develop symptoms and lose their memory and cognitive abilities—or even have personality changes. Yet it happens all too often. And the trend is likely to continue—especially with the youngest of the baby boomer generation getting closer to their 60s, along with the significant rise of obesity and related inflammatory illnesses—such as diabetes—in the general population. While there are several different types of dementing diseases, Alzheimer’s disease (AD) is the most common and accounts for 60-80% of all dementia cases. Most people who are diagnosed with it are 65 or older. However, early-onset Alzheimer’s affects about 200,000 younger people in the U.S.—some of whom are in their 30s and 40s.

Basic Brain Biology in Alzheimer’s Disease

Many years ago, doctors and researchers found that the underlying pathology of AD begins decades before the onset of clinical symptoms. Slowly, certain abnormal neurobiological processes start to take place, including these: While beta amyloid and tau proteins are normally found in our brains, there are abnormal amounts of them in people with AD. The significant accumulation of plaques and tangles cause brain cells to die. Although brain SPECT imaging doesn’t assess the quantity of beta amyloid and tau proteins in the brain, it can show the degree of damage caused by them. In AD patients, SPECT typically shows areas of low blood flow in the temporal lobes, parietal lobes, and posterior cingulate gyrus. Other areas of the brain can be involved as well, depending on the progression of the disease.

Promising New Research in Alzheimer’s Disease

As researchers continue to investigate the molecular underpinnings of this terrible disease, some fascinating results have recently been discovered. Scientists from around the world collaborated on a research study that was recently published in the scientific journal, Nature Medicine. Using positron emission tomography (PET—a type of functional scan, like SPECT) and a tracing agent that attaches to tau proteins, the brains of more than 1,600 people with varying progressions of AD were analyzed. The researchers identified 4 variations in the pattern and spread of tau protein found in the subjects’ brains, and these patterns aligned with the patients’ more pronounced symptoms. The findings from this study include:
  1. 33% of subjects showed the spread of tau primarily in the temporal lobes, which are involved with memory.
  2. 18% had a greater amount of tau in the cortex (grey matter) and this reflected problems with self-control, ability to focus, and difficulties with executive function.
  3. The 3rd variant—30% of the cases—had an accumulation of tau in the visual cortex (back of the brain), which affects one’s orientation to space and the ability to identify shapes, contours, and distances.
  4. An asymmetrical spread of tau across the left hemisphere of the brain was found in 19% of the subjects and reflected their difficulty with language skills.
This study, and others similar to it, have found that Alzheimer’s disease, like so many other brain conditions, is not a simple disorder. Although it is not yet understood why one person would have a particular pattern of tau vs. another, the variations in the underlying pathology can help explain why a universal cure has not been found, despite all the clinical trials that have been conducted so far. This new knowledge may be useful for the development of different types of treatment that can address the varying disease patterns.

Risk Factors for Dementia

Generally speaking, age is the biggest risk factor for dementia. It’s estimated that 50% of all people aged 85 and older will be diagnosed with some form of dementia. Genetics can also play a role in developing AD, especially if someone carries the APO E4 gene, which is associated with overall lower blood flow to the brain. But not everyone who inherits this gene will get AD—in fact, 75% won’t. Aside from factors such as these that are largely out of anyone’s control, lifestyle behaviors are known to reduce the risk of developing Alzheimer’s disease—or another type of dementia. Aside from age and the inheritance of certain genes, healthy lifestyle behaviors such as diet, exercising your body and brain, and positive social connections are known to reduce the risk of developing Alzheimer’s disease.
Click to tweet

Prevention is the Best Cure!

As mentioned above, the pathology of AD and other dementias begins in the brain many years before a person shows symptoms. Therefore, what you do today can have a positive—or negative—impact on your chances of becoming demented down the road. So, if you’ve been on a less-than-healthy path, you can still take steps to make changes that could have big payoffs later on in life. Here are a few recommendations to get you started: You can also look into the Memory Rescue Program to identify any early signs or risks you might have for memory problems. In addition, you’ll learn about more ways you can optimize your brain function now, to reduce your chances of getting Alzheimer’s disease or another type of dementia in the future. Concerns about memory problems and dementia shouldn’t wait. During these uncertain times, your mental well-being is more important than ever! At Amen Clinics, we’re here for you. We offer in-clinic brain scanning and appointments, as well as mental telehealth, remote clinical evaluations, and video therapy for adults, children, and couples. Find out more by speaking to a specialist today at 888-288-9834 or visit our contact page here. What was once thought to be primarily a respiratory illness, COVID-19 has proven to be a formidable foe for the brain as well. While most people recover from the virus within a few weeks, some simply do not. Even months after being infected and getting over the initial symptoms, many people have reported ongoing problems with memory, fatigue, brain fog, and other neurological symptoms, collectively referred to by Amen Clinics as “COVID-Brain.” These “long-haulers” represent approximately 10% of those who were ill with COVID-19. Many of them were never hospitalized nor in high-risk categories for complications from the virus. Research into the underlying mechanisms of the persistent and disruptive neurological symptoms is ongoing and will likely continue for years to come. However, there already are some strong theories about what may be causing brain dysfunction from COVID-19 infections, and the possible links to an increased risk of cognitive decline or dementia in the future.

How COVID-19 Infects Brain Cells

One of the most striking hypotheses described in a research article in the journal Alzheimer’s and Dementia is that SARS-CoV-2, the coronavirus that causes COVID-19, is “neurotropic.” This means that it can directly infect the tissues of the central nervous system, which includes the brain, spinal cord, and nerves. Since the virus is airborne, it can be inhaled via the nose and enter the brain through the olfactory nerve. This nerve gives us our sense of smell, and anosmia—the loss of ability to smell—is often one of the first symptoms of COVID infection. Anosmia can also be an early symptom of Alzheimer’s disease and other types of dementia. It remains to be seen whether or not the damage to the olfactory system from the virus deteriorates its function in the long term. However, an October 2020 research study published in the medical journal Neurology found damage to the olfactory bulb (which connects to the olfactory nerve) in autopsy studies of those who had died from COVID-19.

Inflammation and COVID-19

Another significant concern about the long-term implications of COVID-19’s impact on the brain is the degree of inflammation it can cause. Because it is a new virus that no one had exposure to prior to 2019, humans had no defenses against it. And given its aggressive nature and potential lethality, once a person is infected with it, the immune system goes all out on the attack to fight it. Through complex mechanisms, this results in increased inflammation as the immune system tries to defeat the invading virus. However, a consequence of this process is that, in an effort to protect the brain, the high level of inflammation can actually cause damage to the function of brain cells, including ones involved in memory. Other possible causes of damage to the brain from COVID-19 include complications related to: Even though problems with memory, attention, and other aspects of executive dysfunction have been experienced by both young and old people, some populations are at higher risk than others. For example, those who already have health problems that are linked to increased inflammation, such as diabetes and obesity, may be more vulnerable to a worsening of brain-related problems. Being pre-emptive to protect your health now can make a big difference. People who already have health problems that are linked to increased inflammation, such as diabetes and obesity, may be more vulnerable to a worsening of brain-related problems from COVID-19.
Click to tweet

7 Simple Ways to Lower Inflammation and Boost Your Health

Since the long-term consequences of COVID-19 are becoming increasingly recognized, if you have not been infected with it, it’s imperative that you continue to follow recommended guidelines to protect yourself from this virus. If you have had it—and particularly if you still struggle with lingering symptoms—taking measures to lower inflammation is of utmost importance. The good news is that there are some easy changes you can make that can have a positive impact on your health. Here are 7 simple ways to decrease inflammation in your body and brain:
  1. Increase your consumption of prebiotic foods such as apples, beans, cabbage, artichokes, asparagus, and root vegetables.
  2. Increase probiotics in your diet either through supplements or fermented foods with live bacteria, including sauerkraut, kimchi, pickled fruits and veggies, and kombucha tea (these are often found in the produce section of the grocery store).
  3. Boost your omega-3 fatty acid intake by eating more cold-water fish, such as salmon, mackerel, tuna, and herring, or with supplements.
  4. Limit or avoid alcohol, sugar and refined grains, processed meats, and trans-fats (anything with partially hydrogenated or vegetable shortening on the label).
  5. Take care of your gums! Periodontal (gum) disease can increase inflammation, so be sure to brush your teeth twice a day and floss daily.
  6. Practice stress management with mindfulness, meditation, or prayer.
  7. Engage in some form of exercise every day, but don’t overdo it, because that can actually increase inflammation.
It is widely believed among researchers that uncontrolled inflammation in the brain—regardless of the cause—is a significant risk for developing dementia. Taking the appropriate steps to protect your health, can make a big difference for optimal functioning of your brain now and in the future. COVID-Brain and memory problems are real and can’t wait. During these uncertain times, your mental well-being is more important than ever! At Amen Clinics, we’re here for you. We offer in-clinic brain scanning and appointments, as well as mental telehealth, remote clinical evaluations, and video therapy for adults, children, and couples. Find out more by speaking to a specialist today at 888-288-9834 or visit our contact page here. Medications can help us in many ways. They provide needed support in our bodies and brains for a wide array of physical and mental health conditions. In fact, about half of all American adults are on at least one long-term prescription medication. While modern medicine can work wonders for those who need it, did you know that many common medications can adversely impact your memory by lowering blood flow in the brain or depleting important nutrients that are vital for healthy brain function? Many common medications can lead to memory problems by depleting important nutrients or lowering blood flow to the brain.
Click to tweet
While the following list isn’t exhaustive—some mood meds, general anesthesia, and chemo can affect brain function too—take a look at these 6 common medication categories to see if any of them might be hurting your memory:

6 Medications That May Be Hurting Your Memory

1. Benzodiazepines

Short-term use of medications, such as alprazolam (Xanax), diazepam (Valium), and clonazepam (Klonopin) for treating anxiety can be effective in acute situations because of their calming and sedating effects on the brain. However, prolonged use of benzos like these can lead to confusion and memory loss, along with a host of other problems.

2. Sedative-Hypnotics

Sleep aids like zolpidem (Ambien) and eszopiclone (Lunesta) are typically taken as needed for insomnia. But as with benzodiazepines, the prolonged use of these meds can cause cognitive issues such as memory problems and difficulty with concentration.

3. Opiates

Ideally used only for short-term management of pain after an injury or surgery, these highly addictive meds—Oxycontin and Vicodin are among the more common—can wreak havoc on your body and brain when taken for a long time. In particular, they cause memory impairment and problems with executive functioning.

4. Statins

The most commonly prescribed medications taken by American adults are statins, which are used for lowering cholesterol levels that are deemed too high and can lead to a heart attack or stroke. While many people must take them for health reasons, statins are notorious for depleting co-enzyme Q10 (CoQ10) which is essential for heart and mitochondrial function (mitochondria are the powerhouses in all of our cells). CoQ10 is necessary for protecting our brains from oxidative stress which can lead to brain disease.

5. Beta Blockers

If you have high blood pressure, you may be taking a beta-blocker such as atenolol or metoprolol to help lower your blood pressure. These meds also can reduce levels of the critical nutrient CoQ10. A 2014 research study published in the medical journal, Atherosclerosis, found that lower blood levels of CoQ10 were associated with an increased risk of dementia.

6. Diabetes Medications

Glucophage or Metformin are usually prescribed for insulin resistance in type 2 diabetes. These medications help reduce the high blood sugar levels that are so dangerous to your overall health. The downside is they can also deplete CoQ10 as well as vitamin B12 and folic acid while increasing levels of homocysteine, an amino acid known for its adverse impact on health. Read on to learn more about why this is so important!

B Vitamins and Mild Cognitive Impairment

The University of Oxford conducted an interesting study on the impact certain B vitamins have on participants who had some memory problems and mild cognitive impairment. At the end of the 2-year study, the subjects who were given the vitamins B6, B12, and folate had notably less brain atrophy (shrinkage) AND lower blood levels of homocysteine compared to the placebo group. The added importance of this is that higher levels of homocysteine are associated with inflammation, hardening of the arteries, blood clots, stroke, and dementia.

Your Brain and Memory Can Get Better!

Even if you’re taking these or other medications that make you feel foggy and affect your memory, there are ways you can support and improve your brain function.

Here are 3 quick tips to help you get started:

  1. Brain-healthy diet changes: Eliminate sugar (including artificial sweeteners) along with processed and fried foods.
  2. Daily exercise: Whether it’s walking, lifting weights, or dancing, exercise boosts blood flow to your brain—and entire body!
  3. Dietary supplements to support brain function: B vitamins, curcumins, phosphatidylserine, ginkgo biloba, among others may be helpful. Be sure to check with your doctor first to ensure they won’t interfere with your medications.
Your brain is precious and is the organ of YOU. Taking care of your brain to make it as strong as possible—for as long as possible—is the ticket for protecting your memory. Memory issues, brain fog, and fuzzy thinking can’t wait. Amen Clinics has created a proven Memory Rescue Program that can help you address your risk factors, train your brain, and improve your memory. We are available for in-clinic brain scanning and appointments, as well as mental telehealth, remote clinical evaluations, and video therapy. Find out more by speaking to a specialist today at 888-288-9834 or visit our contact page here. Losing your train of thought mid-sentence? Forgetting why you entered the room? Blanking out on the name of the show you watched last night on Netflix? You may think it’s just the normal aging process, but it could have something to do with the foods you eat. Your brain uses 20% to 30% of the calories you consume, making it is the most energy-hungry organ in your body. Everything you put on the end of your fork matters in terms of your cognitive function. And if you eat a fast-food diet, you’ll have a fast-food memory. Losing your train of thought mid-sentence? Forgetting why you entered the room? Blanking out on the name of the show you watched last night on Netflix? It could have something to do with the foods you eat.
Click to tweet
If you’re struggling with forgetfulness, take a hard look at your diet to see if you’re consuming any of these 7 foods that can contribute to memory problems.

7 Foods That Contribute to Memory Problems

1. Vegetable oils

Safflower oil, corn oil, sunflower oil, and canola oil may sound healthy, but they are all high in omega-6 fatty acids, a type of fat that can be harmful to your cognitive function if you eat them in excess. Consuming too many foods that are high in omega-6 can cancel out the brain benefits of omega-3 fatty acids (those found in foods like salmon, sardines, and walnuts). The optimal ratio is likely under 4-to-1 (omega-6 to omega-3). Most people who eat the standard American diet, which contains high levels of omega-6-rich foods, have an appalling ratio of 20-to-1 or higher. This is bad news for memory. According to a review of 13 scientific studies, when the ratio is skewed too high in favor of omega-6, it’s associated with an increased risk of cognitive decline and Alzheimer’s disease.

2. Sodas and energy drinks

Sodas and energy drinks claim to give you a quick boost, but they could be fueling forgetfulness. A 2013 study shows that sugary beverages have been linked to diabetes, which is associated with a greater risk of Alzheimer’s disease. In 2017, scientists reported new evidence in the Journal of Alzheimer’s Disease linking abnormal insulin levels to Alzheimer’s disease and cognitive decline.  The correlation is so strong, some researchers have labeled Alzheimer’s “Type 3” diabetes. Research has also linked diabetes to decreased blood flow to the brain (the #1 predictor of future memory problems) on brain SPECT imaging, as well as a smaller hippocampus. Even mildly elevated blood sugar levels are a significant problem and associated with brain atrophy, memory problems, and dementia, according to 2013 research in The New England Journal of Medicine.

3. White carbs

White bread, pasta, potatoes, and rice are terrible foods for your memory. They are all high glycemic, which means they cause a quick surge in insulin and blood sugar levels. A 2015 review of the scientific evidence on food and cognitive deficits in Nutrients found that a single high-glycemic meal impairs memory. People with a higher intake of refined carbs and fats have greater impairment on memory tasks. Refined carbs, such as these white foods, also contribute to inflammation, which is recognized as a risk factor for Alzheimer’s disease and other dementias.

4. Fried foods

French fries, fried chicken, doughnuts, and other fried fare are not your friends when it comes to memory. A study of 18,080 people in The Journal of Nutritional Science found that a diet high in fried foods (and processed meats) is associated with lower cognitive scores in memory and learning.

5. Artificial sweeteners

Consuming artificial sweeteners, such as those found in diet sodas, on a regular basis is not a recipe for good recall. It can contribute to chronically high insulin, which increases your risk for Alzheimer’s disease. It also raises the risk of heart disease, diabetes, and metabolic syndrome—all of which have been linked to negative impacts on cognitive function.

6. Excessive alcohol

Drinking too much alcohol can give you a fuzzy memory. For example, alcohol lowers blood flow to the cerebellum, an amazing part of the brain that is associated with thought coordination. In a 43-year follow-up study of more than 12,000 people, nondrinkers did not differ from light drinkers in dementia risk, while heavy and very heavy drinkers had an increased risk. Drinking more hard liquor (gin, rum, vodka, tequila, whiskey, brandy) increased the odds of dementia, whereas imbibing more wine was associated with a lower risk (although wine’s benefit was reversed at high amounts). Relative to non-drinkers and light drinkers, moderate-to-heavy drinkers had a 57% higher risk of dementia—and they got it earlier. A study at Johns Hopkins found that people who drink every day have smaller brains, and when it comes to the brain, size matters!

7. Trans fats

These synthetic fats, or “Frankenfats,” are found in partially hydrogenated vegetable oils, and they have no place in your diet if you want to keep your mind. They are the worst fats associated with memory problems, even in young adults, according to scientific findings in a 2015 issue of Plos One.  They are found in shortening and many processed foods, margarines, commercially prepared fried foods and packaged baked goods, including doughnuts, crackers, and snack foods. Research in the Neurobiology of Aging shows that high consumption of these unhealthy fats is associated with reduced brain volume, cognitive decline, and increased risk of Alzheimer’s disease. Memory problems can’t wait. At Amen Clinics, our Memory Rescue BRIGHT MINDS Program takes a whole-person approach to memory loss and dementia. In addition to brain SPECT imaging to identify any underlying brain health issues, we also look at the biological (including diet), psychological, social, and spiritual factors in your life that may be contributing to memory issues. We are available for in-clinic brain scanning and appointments, as well as mental telehealth, remote clinical evaluations, and video therapy. Find out more by speaking to a specialist today at 888-288-9834 or visit our contact page here. Memory is the fabric of our soul. It makes us who we are and allows us to keep our loved ones close, even when they are far away. Memory houses our joys, our hurts, and all of life’s lessons. It reminds us who is trustworthy and who isn’t, who helped us and whom we need to help. Memory helps us recall important elements of our lives and helps keep us centered and growing. And it’s also what provides us with a sense of purpose that gives our life meaning. When our memory is diminished or damaged, it can rob us of our ability to make good decisions (because we forget important life lessons) and causes us to become disconnected from those we love. Memory problems limit our success at work, steals our independence and ultimately makes us vulnerable to the wolves in society who are out to take advantage of us. Alzheimer’s disease, the most common cause of dementia, robs us of those memories, rendering our lives unrecognizable. Over 5 million Americans are living with Alzheimer’s and that number is expected to roughly triple by 2050. If you want to save your memory and prevent Alzheimer’s disease, you may be engaging in well-documented strategies that protect your physical fitness (such as eating a healthy diet and exercising to improve blood flow) and mental fitness (such as engaging in new learning and mental exercise). There’s a powerful Alzheimer’s prevention strategy you may be overlooking—spiritual fitness. There’s a powerful Alzheimer’s prevention strategy you may be overlooking—spiritual fitness.
Click to tweet

What is Spiritual Fitness?

Spiritual fitness is a new concept in medicine that centers on how psycho-spiritual wellness can reduce the risk of memory loss, mild cognitive impairment, and Alzheimer’s disease. According to BMJ Open, scientific evidence suggests that spirituality and religious involvement can preserve cognitive function as we age. To understand the concept of spiritual fitness, we must first look at the meaning of spirituality. Contrary to what you may think, the notion of spirituality is not necessarily tied to religion. In fact, a growing number of Americans view themselves as spiritual but not religious, according to Pew Research. Belief in God remains strong, with 87% of Americans responding “yes” to a 2017 Gallup Poll that asked, “Do you believe in God?” And 77% of Americans say they pray at least monthly (55% of them say they pray daily). However, U.S. church membership has dropped to 50%. In essence, spirituality has come to mean an individual’s search for a higher power or for something sacred or divine. This search may come in many forms. Regardless of religious affiliation, spiritual fitness encompasses many areas, such as stress reduction, a sense of overall contentment, and having a sense of belonging to something greater than yourself. Learning to accept and forgive yourself and others, having empathy, and being compassionate are core components of psycho-spiritual well-being. On the other side, lower spiritual well-being is associated with mild cognitive impairment and early dementia, according to research in Frontiers in Psychology.

6 Ways to Pump Up Your Spiritual Fitness

1. Harness the power of meditation.

A 2015 study in the Journal of Alzheimer’s Disease shows that a type of meditation known as Kirtan Kriya improves-psycho-spiritual well-being and spiritual fitness, which it says are important for the preservation of cognitive function and the prevention of Alzheimer’s disease. A 2020 study by some of the same researchers suggests that spiritual and religious practices, including Kirtan Kriya meditation, are critical components that enhance cognitive well-being, and in some cases, may reverse cognitive decline. In this study, the researchers conclude, “We hope that this article will inspire scientists, clinicians, and patients to embrace this new concept of spiritual fitness and make it part of every multidomain program for the prevention of cognitive disability.”

2. Make prayer a daily practice.

A wealth of research shows that prayer and meditation have been found to calm stress; improve memory, focus, and mood,; and enhance function in the prefrontal cortex of the brain. The same way you schedule time to work out, make prayer a priority in your appointment book.

3. Put your faith into action.

Regardless of your belief system, make it a central part of your everyday life. Make the effort to flex your spiritual muscle by putting your faith into action. For example, if the tenets of your faith lie in forgiveness, find it in your heart to release the grudges you hold.

4. Look for a spiritual trainer.

Just like you might hire a personal trainer to help you get the most out of your workouts, a mentor can be beneficial to your spiritual life. A mentor could be a pastor, a rabbi, a Zen master, or any other person who can guide you in your spiritual quest. The mentor-mentee relationship isn’t about being told what to do or how to think, rather it’s a way to explore and stretch your spirituality.

5. Serve others.

Being of service to others is a key aspect of a healthy spiritual life. Research suggests that whenever you feel down, anxious, or angry it is best to get outside of yourself to change your state of mind.  Connect meaningful activities and pleasure, such as volunteering for activities you love. For example, if you love table tennis (the world’s best brain sport!), you might enjoy volunteering to keep score at tournaments.

6. Find your purpose.

To strengthen your spiritual fitness, you need to know your purpose in life. Here are 6 simple steps to find your purpose.
  1. Look inward. What do you love to do? (Examples include writing, cooking, design, creating, speaking, teaching, etc. What do you feel qualified to teach others?)
  2. Look outward. Who do you do it for? How does your work connect you to others?
  3. Look back. Are there hurts from your past that you can turn into help for others? (Turn pain into purpose.)
  4. Look beyond yourself. What do others want or need from you?
  5. Look for transformation. How do they change as a result of what you do?
  6. Look to the end. When you die, how do you want to be remembered?
At Amen Clinics, our Memory Rescue BRIGHT MINDS Program takes a whole-person approach to memory loss and dementia. In addition to brain SPECT imaging to identify any underlying brain health issues, we also look at the biological, psychological, social, and spiritual factors in your life that may be contributing to memory issues. We are available for in-clinic brain scanning and appointments, as well as mental telehealth, remote clinical evaluations, and video therapy. Find out more by speaking to a specialist today at 888-288-9834 or visit our contact page here. If you want to preserve your memory and avoid Alzheimer’s disease and other dementias, you need to avoid the common risk factors associated with cognitive dysfunction. Health experts have identified 3 new modifiable risk factors for dementia, according to the 2020 report of the Lancet Commission. These new factors that contribute to increased risk of memory loss and cognitive dysfunction join 9 other risk factors previously identified by the Lancet Commission. The 9 previously identified risk factors are: The 3 new modifiable risk factors are: According to the commission, these 12 risk factors account for approximately 40% of dementias worldwide. The expert panel suggests that preventing or treating these risk factors could potentially delay or avoid dementias, including the most common form, Alzheimer’s disease. Health experts have identified 3 new modifiable risk factors for dementia: traumatic brain injury, excessive alcohol consumption, and air pollution.
Click to tweet

WHAT BRAIN IMAGING REVEALS ABOUT THE NEW RISK FACTORS FOR MEMORY LOSS

At Amen Clinics, which has built the world’s largest database of functional brain scans (over 160,000 and growing), brain SPECT imaging shows how these new risk factors impact memory and cognitive function. Although the Lancet Commission only recently recognized TBIs, heavy alcohol use, and air pollution as contributing factors for dementia, Amen Clinics had already linked these risks to memory problems years earlier. In fact, Amen Clinics has identified the 11 major risk factors that steal your mind and increase the likelihood of memory problems and Alzheimer’s disease. The mnemonic (memory device) BRIGHT MINDS makes it easy to remember them.

THE 11 BRIGHT MINDS RISK FACTORS

B is for blood flow: Problems such as high blood pressure, heart disease, and lack of exercise reduce blood flow to the brain. On SPECT, low blood flow is the # predictor of Alzheimer’s disease. R is for retirement and aging: When you stop learning, your brain starts dying. Less education growing up and no new learning in your adult life are bad for your brain. I is for inflammation: Chronic inflammation is like an internal fire that destroys your mind. G is for genetics: A family history of dementia increases your risk, but it is not a death sentence. Think of it as a wake-up call to get serious about your brain health. H is for head trauma: As you saw above, head injuries, such as concussions, are a silent epidemic that impacts memory. T is for toxins: Exposure to environmental toxins—household cleaning supplies, pesticides, air pollution, alcohol, drugs, and others—can damage the brain and contribute to cognitive dysfunction. M is for mental health: Studies have shown that depression, which the Lancet Commission recognized as a risk factor for dementia, is not the only psychiatric condition associated with memory problems. Bipolar disorder, schizophrenia, post-traumatic stress disorder (PTSD), ADD/ADHD, and chronic stress also significantly increase the risk of memory problems. I is for immunity and infections: Chronic issues, such as autoimmune disorders and infections like Lyme disease, commonly impact memory and contribute to brain fog. N is for neurohormones: Hormonal imbalances, such as thyroid issues, are associated with cognitive impairment and memory problems. D is for diabesity: Having diabetes and/or being obese increases the risk of Alzheimer’s disease. Research in The New England Journal of Medicine shows that even mildly elevated blood sugar levels and pre-diabetes are a significant problem and associated with brain atrophy, memory problems and dementia. S is for sleep: A number of studies, including a 2011 study in JAMA, link sleep problems, such as insomnia and sleep apnea, to a higher risk of memory problems and dementia, but findings in the journal Neurology show that effectively treating these disorders can have a positive impact on memory and brain function. The best way to sharpen your memory, reverse brain aging, and prevent memory loss and Alzheimer’s disease is to eliminate, prevent, or treat all the BRIGHT MINDS risk factors. At Amen Clinics, our Memory Rescue BRIGHT MINDS Program offers a comprehensive approach to memory loss and dementia. In addition to brain SPECT imaging to identify any underlying hidden brain injuries, we also look at the biological, psychological, social, and spiritual factors in your life that may be contributing to memory problems. We are available for in-clinic brain scanning and appointments, as well as mental telehealth, remote clinical evaluations, and video therapy. Find out more by speaking to a specialist today at 888-288-9834 or visit our contact page here. Be honest, is your memory getting worse? Are you forgetting appointments? Do you frequently misplace your keys or phone? Do you often wonder why you came into a room? Are you struggling with brain fog? If you’re concerned about memory problems, you may seek professional help. Unfortunately, given how most doctors approach this issue you can’t count on traditional medicine to rescue your memory. In fact, conventional healthcare professionals often perpetuate a myth about memory loss that actually prevents you from rescuing your memory.

THE MYTH ABOUT MEMORY LOSS

Here’s a common scenario: You’re having difficulty remembering conversations, forgetting where you put your reading glasses, or briefly getting lost driving in familiar areas. So, you see your primary care physician or local neurologist, who asks you a few questions, gives you some short tests and orders an MRI. Based on your results, traditional medical professionals will often tell you the #1 myth about memory loss: “Everyone has memory problems with age. It’s normal.” In reality, losing your memory or developing brain fog in your 40s, 50s, 60s, 70s, or even 80s is common, but it’s NOT normal. The #1 myth about memory loss: “Everyone has memory problems with age. It’s normal.” In reality, losing your memory or developing brain fog in your 40s, 50s, 60s, 70s, or even 80s is common, but it’s NOT normal.
Click to tweet
The report on your MRI comes back as “mild, age-appropriate brain atrophy.” Your doctor tells you that you have “mild cognitive impairment” (MCI) or early Alzheimer’s disease. You’re reassured that it’s common, and you’ll likely retain your personality and long-term memory until later in the illness. You’re encouraged to get your affairs in order, given a prescription for Aricept (a common memory medication that has short term benefits, but loses its effects after 18 months), and told to make a follow-up appointment in 6 months. That’s literally the extent of the work-up in 80-90% of the people who visit Amen Clinics for memory problems after going through the traditional medical system. Before visiting Amen Clinics, they say they received no discussion about eliminating risk factors, exercise, diet, supplementation, or memory training exercises. It’s completely ineffective, heartbreaking, and unconscionable given what we know now.

WHAT’S REALLY HAPPENING IN THE BRAIN BEFORE MEMORY SYMPTOMS APPEAR?

In 2011, the National Institute on Aging (NIA) revised its staging guidelines for Alzheimer’s disease. The old guidelines had 3 stages:
  1. Normal: no symptoms
  2. Mild cognitive impairment: people or relatives have started to notice a problem
  3. Alzheimer’s disease: a significant problem is present and getting worse.
Based on new brain imaging data, the NIA added a new, 4th stage.
  1. Normal
  2. Preclinical: no obvious symptoms, but negative changes can be seen on a brain scan
  3. Mild cognitive impairment
  4. Alzheimer’s disease
Can you see the problem here? You have no symptoms at all, but your brain is already starting to deteriorate. Brain imaging research, including a 2014 study in Neuro-degenerative Diseases, show that negative changes associated with Alzheimer’s disease begin years or even decades before there are any signs of trouble! A person who is diagnosed with Alzheimer’s disease at age 59 likely started to show disconcerting brain changes by 30. And someone who is diagnosed with Alzheimer’s disease in their early 70s likely had evidence of brain deterioration in their 40s. Someone who is diagnosed with Alzheimer’s disease in their early 70s likely had evidence of brain deterioration in their 40s.
Click to tweet
Your brain’s history is NOT its destiny. Even if you have brain fog or trouble remembering now, it doesn’t mean you always will. You can start having a better memory today.

THE MEMORY RESCUE PROGRAM

The best way to sharpen your memory, reverse brain aging, and prevent Alzheimer’s disease and other dementias is to eliminate, prevent, or treat the 11 major risk factors that steal your mind, represented by the mnemonic (a memory device) BRIGHT MINDS. See how many of the following BRIGHT MINDS risk factors you have. B – Blood flow problems: hypertension or pre-hypertension, stroke, cardiovascular disease, cholesterol problems, erectile dysfunction, exercising less than twice a week R – Retirement/Aging: risk increases with age (over 50); a lack of new learning is another important risk factor—when you stop learning, your brain starts dying I – Inflammation: gum disease, high homocysteine or C-reactive protein blood levels, low omega-3 fatty acids G – Genetics: a family member with Alzheimer’s disease or another form of dementia or Parkinson’s disease, or having the Apo E4 gene H – Head trauma: a history of head injuries with or without loss of consciousness; playing contact sports (even without a concussion) T – Toxins: alcohol or drug abuse, exposure to toxins in the environment (toxic mold, pollution) or personal products, cancer chemotherapy, etc. M – Mental health issues: chronic stress, depression, ADD/ADHD, PTSD, bipolar disorder, schizophrenia I – Immunity/Infection Issues – chronic fatigue syndrome, autoimmune issues, such as rheumatoid arthritis or multiple sclerosis; or untreated infections, such as Lyme disease N – Neurohormone imbalances: low thyroid, testosterone (males and females), estrogen and progesterone (females), low DHEA (dehydroepiandrosterone), high cortisol D – Diabesity: diabetes, pre-diabetes, and obesity S – Sleep problems: chronic insomnia and sleep apnea The good news is that almost all of these risk factors are either preventable or treatable. Even the ones that aren’t, such as having a family history of dementia, can be ameliorated with the right memory rescue program. Memory issues can’t wait. Amen Clinics has created a proven Memory Rescue Program that can help you address your risk factors, train your brain, and improve your memory. We are available for in-clinic brain scanning and appointments, as well as mental telehealth, remote clinical evaluations, and video therapy. Find out more by speaking to a specialist today at 888-288-9834. If all our specialists are busy helping others, you can also schedule a time to talk. Blanking out on people’s names, forgetting appointments, having problems with short-term memory—these are classic memory symptoms of early dementia. But memory problems aren’t the only signs of dementia. In fact, there are many other behavioral changes that don’t have anything to do with memory that can be an indicator you’re heading for Alzheimer’s disease or another form of dementia.   Memory problems aren’t the only signs of dementia.
Click to tweet
The neuropsychiatrists at Amen Clinics, the global leader in brain health, have worked with thousands of people who don’t realize their changing behaviors could be warning signs of dementia. For example, a highly successful businessman who had always played by the rules reached out for help after his once-wonderful life started falling apart. In his 50s he suddenly began gambling heavily, having extramarital affairs, and engaging in illegal activities at work. With his gambling and bad investments, he lost millions of dollars, nearly lost his wife of 30-plus years, and got arrested for insider trading. He didn’t know why he was acting so out of character but couldn’t stop himself. At Amen Clinics, his brain SPECT imaging studies showed decreased blood flow and low activity in his frontal lobes and temporal lobes, a pattern commonly seen in a type of dementia called frontotemporal dementia (FTD). Even though the man didn’t have any problems with forgetfulness, his brain scans helped him understand what was causing his behavior changes, and he got started on a memory rescue program before forgetfulness emerged. Treatment for Alzheimer’s disease and other forms of dementia is more effective when it is started early. That’s why you need to be aware of possible indicators of this dreaded disease.

Here are 9 early warning signs of dementia you should investigate.

1. Breaking the law.

Law-abiding citizens who suddenly begin stealing, trespassing, or driving recklessly may be exhibiting early signs of dementia, in particular FTD. A 2015 study in JAMA Neurology found that in 14% of people with FTD, breaking laws was the first sign of dementia.

2. Eating weird stuff.

Changes in appetite and the foods you crave are an early warning sign of dementia, according to a 2015 Japanese study in Plos One. Some people with dementia will eat food that is rancid or spoiled or may eat non-food objects, such as flowers. These odd changes may be due to the fact that dementia attacks parts of the brain that regulate appetite and taste buds. A letter to the editor published in a 2011 issue of Journal of the American Geriatrics Society describes a disturbing case of an 83-year-old woman with mild to moderate dementia eating her own feces.

3. Falling more frequently.

Do you find yourself tripping or falling more often? Be aware that a 2013 brain imaging study in the journal Neurology that involved 125 older adults found that those who fell most frequently were more likely to have the early onset of Alzheimer’s disease. According to the study, falls as well as changes in gait may precede any cognitive symptoms of Alzheimer’s. Other findings in JAMA Neurology found that poor physical performance in a variety of areas—walking, going from sitting to standing, balancing while standing, and grip strength—increases the risk of dementia in people over 90 years of age. As dementia progresses, fine motor skills begin to decline and mobility problems increase, making falls even more common.

4. Gum disease.

The human mouth plays host to an estimated 700 different species of bacteria. The bacteria that lead to gum disease are also linked to the development of dementia, including Alzheimer’s disease, according to a 2020 study in the Journal of Alzheimer’s Disease. A growing body of research, including findings in the Journal of Periodontology, has shown that periodontal (gum) disease is a risk factor for dementia. Gum disease is associated with inflammation, which has been linked with an increased risk of Alzheimer’s. Be sure to brush your teeth twice a day after meals and floss daily: Flossing your teeth is a brain health and memory exercise! And see a dentist regularly for checkups and cleanings.

5. Inability to pick up on sarcasm.

If sarcastic remarks are going over your head, it may be related to dementia, according to 2009 brain imaging research from the University of California, San Francisco. This study shows that the ability to discern sarcasm and other ironic speech in face-to-face encounters is diminished in people with Alzheimer’s or FTD.

6. Engaging in compulsive behaviors.

An unexpected sign of early dementia in some people is a tendency to develop new compulsive behaviors or rituals. For example, becoming a hoarder later in life may signal trouble. Research from UCLA that looked at patients with FTD or Alzheimer’s disease found that 38% of those with FTD and 10% of those with Alzheimer’s exhibited compulsive behaviors. More recent findings in The Journal of Neuropsychiatry suggest that in people with early FTD, these behaviors are more likely impulse-driven due to harmful changes in the frontal lobes, which are heavily involved in impulse control.

7. Your sense of smell is off.

Are you unable to distinguish scents like cinnamon, baby powder, or gasoline? This could be an early warning sign of Alzheimer’s. According to a 2018 study in Biosensors, having trouble with sense of smell (called anosmia) is one of the earliest preclinical symptoms of Alzheimer’s. Other research in the Journal of Alzheimer’s Disease has found that the brains of people with olfactory dysfunction often have the same harmful changes as those seen in Alzheimer’s patients. There is evidence, including a 2016 study from Aristotle University in Greece, that repeated exposure to certain odors can improve the ability to smell. Some suggested scents from essential oils include rose, lemon, cloves, and eucalyptus.

8. Having depression.

Depression doubles the risk of cognitive impairment in women and quadruples it in men. Research in the Archives of General Psychiatry evaluated 5,781 elderly women with tests of mood and memory. Women with 3-5 depressive symptoms were at 60% greater odds for cognitive deterioration, and women with 6 or more depressive symptoms were 230% more likely to have problems! The researchers concluded that depression in older women is associated with both poor cognitive function and subsequent cognitive decline. Research in the International Journal of Geriatric Psychiatry shows that late-life depression may, in fact, be a precursor to Alzheimer’s disease. It is critical to get depression treated in order to keep your mind. Late-life depression may be a precursor to Alzheimer’s disease.
Click to tweet

9. Having ADHD or other untreated mental health problems.

A 2019 study in the Journal of Attention Disorders shows that adults with ADHD are over 3 times more likely to develop dementia compared with those who don’t have ADHD, which affects about 4.4% of American adults. Multiple studies have shown that other untreated mental health disorders significantly increase the risk of memory problems. Research shows increased dementia risk with: Treating mental health disorders can help save your memory. Adults with ADHD are over 3 times more likely to develop dementia compared with those who don’t have ADHD.
Click to tweet
Depression, ADD/ADHD, memory loss, and other mental health issues can’t wait. At Amen Clinics, we’re here for you. We offer in-clinic brain scanning and appointments, as well as mental telehealth, clinical evaluations, and therapy for adults, teens, children, and couples. Find out more by speaking to a specialist today at 888-288-9834 or visit our contact page here.

Two months after beating COVID-19, a 60-year-old woman was experiencing extreme fatigue and depression so severe she was contemplating suicide. In an article for the BBC, the patient’s doctor said the woman experienced ongoing confusion among other bothersome symptoms. The woman told her doctor, “COVID has killed me.” It hadn’t physically taken her life, but it had stolen her mind and left her with no will to live.

While most people are worried about the threat of respiratory failure from the novel coronavirus, there is another invisible risk that could have more lasting consequences for survivors.

Some in the medical community are calling it “long-haul COVID,” but here at Amen Clinics, we call it COVID-Brain.

WHAT IS COVID-BRAIN?

According to a 2020 study in Brain, Behavior, and Immunity, 36.4% of COVID-19 patients develop neurological symptoms. Another 2020 study appearing in the New England Journal of Medicine that looked at 64 consecutive COVID-19 patients in France found that 84% of them exhibited neurological symptoms.

Amen Clinics defines COVID-Brain as the cognitive and psychiatric problems the virus causes that attack the brain and steal the mind.

Amen Clinics defines COVID-Brain as the cognitive and psychiatric problems the virus causes that attack the brain and steal the mind.
Click to tweet

Among the symptoms seen in patients with COVID-19 are confusion, headaches, loss of smell and taste, tingling sensations, strokes, aphasia, and seizures. But these acute symptoms aren’t the only ones associated with the illness.

A February 2021 editorial in The Lancet Psychiatry reported that “there is no doubt that the COVID-19 pandemic is bad for mental health.”

In a November 2020 study in the same journal, researchers found that 1 in 5 COVID-19 patients with no previous history of psychiatric illness developed a mental illness within the first 90 days of their diagnosis. The most common psychiatric issues noted? Anxiety disorders, insomnia, and dementia.

For this large-scale study, researchers analyzed the electronic health records of 69 million people in the US, including 62,354 with a COVID-19 diagnosis. The COVID-mental health connection wasn’t a one-way street. People who had a psychiatric diagnosis in the previous year had a higher risk of being diagnosed with COVID-19.

Other studies have pointed to additional negative outcomes from COVID-19. In the Journal of Alzheimer’s Disease, a 2020 study reveals that long-term consequences of COVID-19 may include:

Some research points to subsequent learning problems in both children and adults. The findings are so disturbing some experts are warning that a second pandemic of neurocognitive and neuropsychiatric problems is on the horizon.

HOW DOES COVID-19 ATTACK THE BRAIN?

In order to better understand the aftereffects of the illness, scientists are using brain imaging to look for abnormalities. Emerging research suggests COVID-19 can cross the blood-brain barrier, a lining that typically protects the brain from viruses and other foreign invaders. Once inside the brain, it can cause damage in a variety of ways.

For example, a 2020 paper in Acta Physiologica, has found that attention problems and memory deficits following infection with the virus are linked to damage in the hippocampus and cortical regions. The hippocampus is involved in mood, memory, and learning.

Brain imaging tests performed on 11 of the patients in the New England Journal of Medicine study mentioned above revealed low blood flow in the frontotemporal lobes in all of them. On brain SPECT imaging, hypoperfusion in the frontal lobes has been associated with inattention, distractibility, impulsivity, and forgetfulness.

Other scientific findings suggest the virus may disrupt the production of neurotransmitters, such as dopamine and serotonin. These neurochemicals play an important role in mood control, motivation, and attention span.

The Alzheimer’s Association is partnering with scientists worldwide on a study to better understand the long-term consequences of COVID-19 on the brain and cognitive function. It remains to be seen if COVID-19 may cause neurobiological changes typically associated with Alzheimer’s disease and other forms of dementia.

THE CHRONIC EFFECTS OF COVID BRAIN

As devastating as the pandemic has been so far, it could leave a lasting legacy of brain dysfunction. With over 5 million confirmed cases of COVID-19 in the U.S. and many more to come, this could mean millions of Americans will be left with brain issues that can impair every aspect of their lives. Considering the brain is the organ of thinking, feeling, and loving, it could impact the ability to learn in school, achieve success at work, and maintain healthy relationships.

How can you counteract this impending tsunami of brain-related problems?

The authors of the Journal of Alzheimer’s Disease study on the neurobiology of COVID-19 mentioned earlier suggest it would be helpful for survivors who are experiencing lingering cognitive issues, brain fog, or poor attention to undergo neurocognitive testing.

“Patients with low scores in certain cognitive domains can consider receiving brain rehabilitation in order to return to their baseline level of cognitive capacity. By doing so, they would reduce their risk for developing a worse case of age-related cognitive decline later in life,” they write.

Similarly, anyone who has had the illness should be aware of any new or worsened symptoms of depression, anxiety, OCD, or PTSD and be screened by a mental health professional. Considering that COVID-19 attacks the brain, it is critical to look at the brain as part of the screening process. SPECT, a functional brain imaging technology that measures blood flow and activity in the brain, can detect abnormal brain patterns associated with psychiatric conditions and cognitive dysfunction. Getting evaluated by an integrative or functional medicine physician can also help. These medical professionals can perform labs to see if chronic infections or inflammation are contributing to issues.

When COVID-Brain strikes, getting a comprehensive evaluation and a personalized treatment plan and ongoing support from the world’s leader in brain health is the key to getting your life back and feeling like yourself again.

COVID-Brain is real, and the mental and cognitive health issues that linger following a COVID-19 diagnosis can’t wait. At Amen Clinics, we’re here for you. Dr. Mark Filidei, the Director of Integrative/Functional Medicine at Amen Clinics, is treating patients with COVID-Brain and long-haul symptoms. In addition, we offer in-clinic brain scanning and appointments, as well as mental telehealth, remote clinical evaluations, and video therapy for adults, children, and couples. Find out more by speaking to a specialist today at 888-288-9834 or visit our contact page here.

Download COVID-Brain eBook Banner

Here’s a common scenario: You’re having difficulty remembering conversations, forgetting where you put your reading glasses, or briefly getting lost driving in familiar areas. What do you do? If you’re like most people struggling with memory problems, you probably visit your primary care physician or a local neurologist.

It sounds like the logical thing to do, but here’s why it’s the wrong approach.

WHAT’S WRONG WITH THE OLD APPROACH TO MEMORY COMPLAINTS?

A traditional family doctor or neurologist will likely ask you a few questions, give you some short tests, orders an MRI (magnetic resonance imaging), and tells you, “Everyone has memory problems with age. You’re normal.”  It’s also common for family members, friends and even medical professionals to downplay forgetfulness.

A week or so later, you meet again with your doctor, who says that the report on your MRI comes back as “mild, age-appropriate brain atrophy.” Your doctor tells you that you have “mild cognitive impairment” (MCI).  You’re reassured that it’s common, and you’ll likely retain your personality and long-term memory until later in the illness. You’re encouraged to get your affairs in order, given a prescription for Aricept (donepezil, a common memory medication that research shows has short-term benefits, but loses its effects after 18 months), and told to make a follow-up appointment in 6 months. 

Typically, there’s no discussion about common (and fixable) causes of forgetfulness, how to eliminate risk factors, or how to enhance memory through exercise, diet, supplementation, and memory training exercises.

That’s literally the extent of the work-up in 80-90% of the cases that eventually come to Amen Clinics from the traditional medical system. It’s completely ineffective, heartbreaking… and unconscionable given what we know now.

THE NEED FOR A NEW APPROACH TO MEMORY PROBLEMS

Until recently, healthcare professionals assessing the presence of memory problems in patients classified their cognitive functioning as: (1) normal with no symptoms; (2) mild impairment observed by patients or their families; or (3) Alzheimer’s disease, in which dementia was becoming significant and getting worse.

The National Institute on Aging announced a significant change in 2011. Based on new brain imaging data, they added a new “preclinical” level. As a result, the current staging guidelines are:

  1. normal
  2. preclinical: no obvious symptoms, but negative changes can be seen on brain scan
  3. mild cognitive impairment
  4. Alzheimer’s disease

Can you see the problem here? A growing body of research, including a 2014 study in Neuro-Degenerative Disorders, shows that long before symptoms develop, your brain may already be starting to deteriorate, years or even decades before there are any signs of trouble!

A UCLA study found that 95% of people with Alzheimer’s are not diagnosed until they are in the moderate to severe stages of the disorder. Yet the brain of a person diagnosed with Alzheimer’s disease at age 59 likely started to show signs of deterioration by the time that person turned 30. 

No matter your age, memory symptoms should be taken seriously. Developing brain fog or feeling as if your memory is slipping when you are in your 40s, 50s, 60s, 70s or even 80s is common, but it’s not normal. It is a sign of impending doom. Ten years after you notice a problem (called subjective cognitive decline), there is an estimated 70-100% chance of your getting worse and slipping into dementia.

But while it is true that memory issues are common with age, they are not inevitable. In the “presymptomatic stage,” when memory problems are minor, help is likely to be most effective. If you’re struggling with your memory, even if it seems minor, now is the time to get serious about your brain’s health.

A BREAKTHROUGH CONCEPT: MEMORY RESCUE

After over 30 years of experience looking at the brain with SPECT imaging at Amen Clinics, together with the latest scientific research, it is clear that the traditional approach to memory problems is misguided and leads to unnecessary disease and disability.

Just as many tributaries feed a river that is about to flood and destroy a community, the physicians at Amen Clinics have discovered that there are many different causes of memory loss. It is no longer accurate to talk about mild cognitive impairment or Alzheimer’s disease as single entities, with single causes, just as Amen Clinics’ brain imaging work has shown it is no longer accurate to talk about a single type of depression, addiction, ADD/ADHD, or obesity.

The ability to identify and address each of the potential causes of memory problems allows for the development of a plan to prevent or even reverse these devastating issues.  

At Amen Clinics, we’re here for you. We have developed a comprehensive Memory Rescue program that combines cutting-edge brain imaging and other diagnostic tools with complete wrap-around services to get to the root of your memory problems and to develop a targeted treatment plan and follow-up care. Find out more by speaking to a specialist today at 888-288-9834. If all our specialists are busy helping others, you can also schedule a time to talk.