
6 Signs You May Need Mental Health Help
Facebook-f X-twitter Youtube TLDR: Mental health conditions affect more than 1 in 5 U.S. adults, yet warning signs are frequently missed because they emerge gradually
What if you could substantially cut your dementia risk simply by making simple lifestyle changes? According to newly published research, dementia prevention, including Alzheimer’s prevention, may be possible through basic steps like changing harmful habits and seeking preventative care.
The study, published in The Lancet by the Lancet Commission on Dementia, found that nearly 50% of global cases of dementia can be delayed or prevented altogether by eliminating, treating, or reducing 14 risk factors.
Reducing risk for various types of dementia, such as Alzheimer’s disease, is more important than ever as our country’s aging population grows. Modifiable risk factors are the easiest way to help prevent these cases—which are expected to double by 2050 in the U.S. alone.
The Lancet’s findings centered around 14 risk factors that contribute to developing dementia symptoms. Let’s look at some of the research behind each one.
Conversely, continuing to learn and keeping the mind active—at any age—has been associated with lower dementia risk.
In fact, hearing loss may be an early dementia symptom. But those who employ hearing aids have been shown in studies to be less likely to develop dementia and experience fewer memory and thinking problems.
One study noted that hypertension is associated with early cognitive deterioration, which can then progress to dementia and stroke within a few years.
The AHA adds that current smokers are 30% more likely to develop dementia and 40% more likely to develop Alzheimer’s disease. Being a heavy smoker increases this risk further—by a whopping 34% for every pack (20 cigarettes) a person smokes per day.
Fortunately, quitting can help reverse this effect. The AHA pointed to a study showing that, after 9 years of avoiding cigarettes, a former smoker’s risk drops to the same level as a person who never smoked.
With more than 40% of Americans meeting the criteria for obesity in 2020, this is likely to become a widespread danger in the years ahead.
This risk was higher for men than women. But the correlation was present regardless of when the depression was diagnosed—in early, middle, or late life.
It concluded that, for older adults, more sedentary time was significantly associated with higher incidence of all types of dementia, including Alzheimer’s disease.
The organization points to further overlaps, such as reduced glucose metabolism in the brains of people with Alzheimer’s disease, possibly caused by nerve cell death. Meanwhile, buildup of beta amyloid plaques in Alzheimer’s-affected brains may disrupt insulin receptors and insulin production, triggering insensitivity to insulin in brain cells.
These are not surprising findings, since alcohol damages the brain in a multitude of alarming ways: shrinking volume, lowering blood flow, inducing atrophy, and reducing the number of new brain cells.
Some studies have estimated that moderate and severe TBIs increase the risk of dementia between 2- and 4-fold. And multiple incidents of even mild TBIs over time (as professional athletes or members of the military might experience) are associated with high risk for the type of dementia called chronic traumatic encephalopathy (CTE).
In light of this evidence, researchers estimated that as many as 188,000 cases of dementia per year might be due to PM2.5.
They may also struggle with psychiatric disorders, suicide, and altered brain development.
However, preventive actions—such as regular eye exams, eyeglasses, and surgery for conditions like cataracts—can reduce risk.
Almost 20 years before The Lancet’s latest study results, Dr. Daniel Amen of Amen Clinics presented similar findings in his 2005 groundbreaking book, Preventing Alzheimer’s. Later, in his 2017 book, Memory Rescue, he shared a list of 11 risk factors for memory loss, known by the acronym BRIGHT MINDS:
The good news is, research shows that many risk factors for dementia can be addressed. And because brain changes can arise decades before Alzheimer’s symptoms appear, it’s a good idea to eliminate, prevent, or alter those risk factors as early as possible.
Many strategies to help counteract these risk factors are easy to adopt. Try any or all of the following:
Dementia doesn’t have to be an inevitable or “normal” part of aging. It’s never too early (or too late) to become more vigilant about your health, ensuring the proper preventative care and lifestyle choices.
Caring for your brain and body now—no matter what your age—will help reduce your risk of cognitive decline and dementia in the years and decades to come.
Dementia prevention, intervention, and care: 2024 report of the Lancet Standing Commission. Livingston, Gill et al. The Lancet, Volume 404, Issue 10452, 572 – 628. https://www.thelancet.com/commissions/dementia-prevention-intervention-care
Sharp ES, Gatz M. Relationship between education and dementia: an updated systematic review. Alzheimer Dis Assoc Disord. 2011 Oct-Dec;25(4):289-304. doi: 10.1097/WAD.0b013e318211c83c. PMID: 21750453; PMCID: PMC3193875.
Alzheimer’s Society, Hearing loss and the risk of dementia, https://www.alzheimers.org.uk/about-dementia/managing-the-risk-of-dementia/reduce-your-risk-of-dementia/hearing-loss
Sierra C. Hypertension and the Risk of Dementia. Front Cardiovasc Med. 2020 Jan 31;7:5. doi: 10.3389/fcvm.2020.00005. PMID: 32083095; PMCID: PMC7005583.
Smoking harms the brain, raises dementia risk – but not if you quit, By Laura Williamson, American Heart Association News, https://www.heart.org/en/news/2021/07/06/smoking-harms-the-brain-raises-dementia-risk-but-not-if-you-quit
Nianogo RA, Rosenwohl-Mack A, Yaffe K, Carrasco A, Hoffmann CM, Barnes DE. Risk Factors Associated With Alzheimer Disease and Related Dementias by Sex and Race and Ethnicity in the US. JAMA Neurol. 2022;79(6):584–591. doi:10.1001/jamaneurol.2022.0976
Elser H, Horváth-Puhó E, Gradus JL, et al. Association of Early-, Middle-, and Late-Life Depression With Incident Dementia in a Danish Cohort. JAMA Neurol. 2023;80(9):949–958. doi:10.1001/jamaneurol.2023.2309
Raichlen DA, Aslan DH, Sayre MK, Bharadwaj PK, Ally M, Maltagliati S, Lai MHC, Wilcox RR, Klimentidis YC, Alexander GE. Sedentary Behavior and Incident Dementia Among Older Adults. JAMA. 2023 Sep 12;330(10):934-940. doi: 10.1001/jama.2023.15231. PMID: 37698563; PMCID: PMC10498332.
Alzheimer Society of Canada, Diabetes and Dementia, https://alzheimer.ca/en/about-dementia/how-can-i-prevent-dementia/diabetes
News Release: Head Injury 25 Years Later – Penn Study Finds Increased Risk of Dementia, https://www.pennmedicine.org/news/news-releases/2021/march/head-injury-25-years-later-penn-study-finds-increased-risk-of-dementia
Shively S, Scher AI, Perl DP, Diaz-Arrastia R. Dementia resulting from traumatic brain injury: what is the pathology? Arch Neurol. 2012 Oct;69(10):1245-51. doi: 10.1001/archneurol.2011.3747. PMID: 22776913; PMCID: PMC3716376.
National Institutes of Health, Air pollution linked to dementia cases, https://www.nih.gov/news-events/nih-research-matters/air-pollution-linked-dementia-cases
National Institute on Aging, Vision impairment is associated with as many as 100,000 U.S. dementia cases, https://www.nia.nih.gov/news/vision-impairment-associated-many-100000-u-s-dementia-cases
Ferguson, Erin L., et al. “Low-and high-density lipoprotein cholesterol and dementia risk over 17 Years of follow-up among members of a large Health care plan.” Neurology 101.21 (2023): e2172-e2184. https://doi.org/10.1212/WNL.0000000000207876

Facebook-f X-twitter Youtube TLDR: Mental health conditions affect more than 1 in 5 U.S. adults, yet warning signs are frequently missed because they emerge gradually
Facebook-f X-twitter Youtube TLDR; ADHD is a brain-based disorder that is frequently misdiagnosed or undetected for years because its symptoms overlap with dozens of other
Sally was 40 years old when she sought care at Amen Clinics for mental health issues. For years, she had been struggling with troublesome symptoms, including a short attention span, distractibility, disorganization, and restlessness.
These are all symptoms associated with attention deficit hyperactivity disorder (ADHD), also known as attention deficit disorder (ADD). However, Sally didn’t think adults could have ADD/ADHD, so she wasn’t interested in hearing about treatment for this common condition.
This could have been the end of her journey, and she would have continued suffering from her symptoms. But a brain scan changed everything.
Scientists have long believed that atypical activity levels in the brain are tied to ADHD. Neuroimaging research published in 2024 confirms that abnormal brain function leads to the behavioral symptoms seen in ADHD.
In this blog, you’ll discover how brain SPECT scans can help people understand why they are experiencing mental health problems. Plus, you’ll learn how brain scans can aid mental health professionals in treating ADHD and other conditions.
Although Sally wasn’t interested in learning about adult ADHD treatment options, she was intrigued about seeing how her brain was functioning. That’s why she decided to get a SPECT scan.
Sally underwent two brain scans—one at rest and the other while she performed a concentration task. The results showed good overall brain activity when she was at rest.
When she tried to concentrate, however, she experienced a reduction in brain activity. This is the opposite of what occurs in a healthy brain. The decrease was especially pronounced in the prefrontal cortex (PFC), an area involved in attention and organization.
When Sally saw her scans, she burst into tears and asked, “You mean, it’s not all my fault?”
What the brain scans showed was that none of the symptoms she was experiencing were her fault. Her short attention span, disorganization, and distractibility weren’t due to a lack of willpower or a lack of effort. They were related to abnormal brain function.
Sally realized that having ADHD is like needing glasses. Are people who wear glasses stupid, lazy, or just not trying hard enough to see better? Of course not!
Similarly, people with ADHD aren’t stupid, lazy, or not trying hard enough. They just need help to increase activity in their prefrontal cortex, so they can focus better.
Sally did very well on an ADD/ADHD treatment plan that helped turn her life around. But if she had never seen her brain scan, she probably never would have gotten the help she needed.
Did you know that psychiatry is the only medical field that doesn’t look at the organ it treats? This means that people like Sally often go undiagnosed or misdiagnosed for years while their symptoms worsen.
Because mental health professionals don’t look at the brain, it means they have to rely on guesswork to diagnose and treat patients with symptoms of ADD/ADHD.
It doesn’t have to be this way. As in Sally’s case, brain scans can make a major difference.
What is SPECT? Single photon emission computed tomography (SPECT) is a nuclear medicine imaging technique that measures blood flow and activity in the brain. It helps take the guesswork out of psychiatry.
While MRI and CT brain imaging studies show the structure of the brain, SPECT brain scans show how it functions. Basically, SPECT shows areas of the brain with:
In Sally’s case, it showed that activity was too low in the prefrontal cortex while she was concentrating. It can also reveal signs of head trauma, exposure to toxins, and drug and alcohol abuse—all of which can contribute to symptoms associated with ADD/ADHD.
The health of your brain plays a major role in your ability to focus, pay attention, and be organized. There is no way to know about the health of your brain unless you look at it.
One neuroimaging study in The Lancet Psychiatry involving brain scans from over 3,200 patients found differences in brain function in people with ADHD.
Most psychiatric illnesses are diagnosed based on symptom clusters—the same way they have been diagnosed for over 100 years. SPECT brain imaging adds an objective, biological component to give doctors important additional information for a more accurate diagnosis.
Common symptoms of ADD/ADHD include:
Looking at the brain helps physicians know what is causing those symptoms. Research published in Radiology indicates that functional brain imaging can identify ADHD.
Brain imaging shows that ADD/ADHD is not a single or simple disorder. In fact, there are 7 types of ADD/ADHD. Each type needs distinctive treatment. Knowing your type, or your child’s type, is the key to getting the most effective treatment. The 7 types of ADD are:
Seeing the brain helps people with ADD/ADHD understand that their lack of impulse control, inattention, or disorganization aren’t signs of weakness or personal failure. Realizing that these symptoms are biological in nature can help people overcome feelings of guilt and shame.
When people see their brain scan, they can no longer deny that they have ADD/ADHD. It helps them understand that their condition is real. This knowledge motivates them to take action to treat it.
When people see their SPECT scans compared to healthy SPECT scans, they tend to develop brain envy. That’s what happened to Sally. Wanting a better brain motivated her to start taking better care of her brain, which helped minimize her symptoms.
With a comprehensive evaluation that includes brain imaging, there is no need for guesswork. People with ADD/ADHD can get a more effective treatment plan that is personalized for their individual needs.
Sally’s treatment plan included nutritional interventions, an exercise plan, a sleep program, targeted supplements, and medication.
After seeing her brain, Sally was more encouraged to follow her treatment plan, which helped decrease her symptoms of ADD/ADHD.
Seeing before-and-after scans of patients who have improved their brain health and overcome ADD/ADHD offers hope to people who are struggling with symptoms that are holding them back.
To help you understand more about ADD/ADHD, here are some answers to common questions.
Healthcare providers who are qualified to give ADHD screening tests and to make an ADHD diagnosis include:
Most providers can treat ADHD with behavioral therapy or lifestyle modifications. However, the only ones who are qualified to prescribe medications, such as stimulants, are psychiatrists and other physicians.
The professionals at Amen Clinics have built the world’s largest database of functional brain scans related to behavior—over 250,000 brain scans and growing—making it the best in the world. Over the past 30-plus years, Amen Clinics has performed SPECT scans on patients ranging from 9 months of age to 105 years old from more than 155 countries.
This brain-based process produces better-than-average results. Based on outcome studies, 85% of patients report improved quality of life after being treated at Amen Clinics.
You can get tested for ADHD locally by visiting any of the healthcare providers listed above. Where can you get tested for ADHD if you also want to get a SPECT scan? If you’re interested in getting a brain scan for a more accurate diagnosis and more effective treatment plan, consider visiting one of Amen Clinics’ 11 locations.
Amen Clinics has outpatient facilities in the following metro areas: Atlanta, Chicago, Dallas/Fort Worth, Los Angeles, Miami/Ft. Lauderdale, New York, Orange County, Phoenix/Scottsdale, San Francisco Bay Area, Seattle, and Washington DC.
Healthcare providers use a variety of ADHD diagnostic tools, screening evaluations, and self-assessments, such as:
Norman, L. J., Sudre, G., Price, J., & Shaw, P. (2024). Subcortico-cortical dysconnectivity in ADHD: A voxel-wise mega-analysis across multiple cohorts. American Journal of Psychiatry. https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.20230026
Huaiqiang Sun, Ying Chen, Qiang Huang, Su Lui, Xiaoqi Huang, Yan Shi, Xin Xu, John A. Sweeney, Qiyong Gong. Psychoradiologic Utility of MR Imaging for Diagnosis of Attention Deficit Hyperactivity Disorder: A Radiomics Analysis. Radiology, vol. 287, No. 2, 2017. https://doi.org/10.1148/radiol.2017170226
Hoogman, Martine et al. Subcortical Brain Volume Differences in Participants with Attention Deficit Hyperactivity Disorder in Children and Adults: A Cross-Sectional Mega-Analysis.
The Lancet Psychiatry, Vol. 4, Issue 4, 310 – 319, 2017. https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(17)30049-4/abstract

Facebook-f X-twitter Youtube TLDR: Mental health conditions affect more than 1 in 5 U.S. adults, yet warning signs are frequently missed because they emerge gradually
Facebook-f X-twitter Youtube TLDR; ADHD is a brain-based disorder that is frequently misdiagnosed or undetected for years because its symptoms overlap with dozens of other
OCD can often be casually dismissed as a strictly behavioral problem that has to do with being overly organized, neurotic about cleanliness, and a perfectionist to the point of exhaustion.
Could all of those be true? Yes.
But that’s just scratching the surface of how OCD impacts the people living with the condition and their loved ones who are struggling to understand it. An overwhelming and all-consuming anxiety often comes with living with OCD.
As the fourth most common mental disorder, OCD impacts about 3% of the population at some point in their lifetime which equals millions of people. Words can have the greatest impact on whether they believe they’re worth seeking help.
Learning how to help someone with OCD can make all the difference in seeking support and getting the right treatment. Knowing what not to say is part of the equation.
At Amen Clinics, we have worked with thousands of patients struggling with OCD. Many of them have shared hurtful comments they have heard from friends, colleagues, and loved ones. This blog will reveal the phrases that sting the most and are most detrimental to the healing process.
Obsessive-compulsive disorder (OCD) is a chronic mental health condition that causes uncontrollable thoughts, reoccurring behaviors, and ruminating obsessions. It is associated with high levels of anxiety, but it is not currently categorized as an anxiety disorder.
Here are some obsessions and compulsions commonly associated with OCD:
With OCD being so widespread, many people either know someone with OCD or experience it themselves. However, despite how common it may seem, OCD is often misunderstood or misdiagnosed.
This is why it’s so important to start understanding from a place of empathy and learn what to say to someone with OCD.
Though this one may seem helpful in getting them help, it can come off as dismissive and simple. Some people with OCD can’t “just stop thinking about it and go to therapy” when their condition is often consumed with mental and physical obstacles.
Oversimplifying OCD can do more harm than good as intrusive thoughts can trigger intense anxiety and trying to suppress it can make symptoms even more persistent.
“I understand this is a difficult time for you. What is the biggest obstacle for you to seek treatment?”
This acknowledges the difficulty of their lived experience and opens the door for them to share what they need from you to get help.
Comparing obsessive-compulsive disorder to little quirky behaviors diminishes the seriousness of this disorder. OCD is not about harmless habits or personality preferences.
This mental health condition can be debilitating when you can’t perform certain compulsions. This leads to a cycle of anxiety and compulsions that have serious ramifications on their mental and physical health and well-being.
“I know OCD is more than a habit or little quirks. I’m here to listen if you need or want to talk about anything.”
This shows you understand OCD is a serious condition and you’re willing to be a supportive listener when they need it most.
OCD isn’t as simple as overreacting. And assuming it is easy to resolve actually invalidates OCD sufferers’ experiences and feelings.
For those struggling with the disorder, the fears and compulsions are very real and can cause significant emotional pain. What might seem like an overreaction to you is often a desperate attempt for those living with OCD to alleviate overwhelming anxiety.
“I know this is negatively affecting you and I want to help figure out a way to work through it together.”
This approach validates their feelings, offers a sense of partnership in facing their challenges, and builds trust for them to know they can communicate with you about it.
Asking someone with OCD to communicate better is vague and not the most helpful way to make progress in helping them through their diagnosis.
OCD is rooted in anxiety and fear, so supporting them during a complex journey that often requires therapy and coping strategies can make all the difference.
“I know it’s not easy to communicate all the time, so maybe we can create a code word to know when you’re feeling overwhelmed.”
This acknowledges the difficulty of letting go, offers support rather than judgment, and gives you an opportunity to bond with them in their most vulnerable moments.
Using this disorder as an adjective to describe being meticulous, organized, or persistent is not only inaccurate but also dismissive of real challenges.
OCD is not about being overly tidy or having neurotic habits. It’s about experiencing obsessions and compulsions to cope with mental distress.
“I respect what you’re going through and want to help you focus on what we can change or improve right now.”
This way, you can acknowledge what they’re struggling with and show respect for their challenges. It lets them know you’re willing to take some of the burden rather than making them feel like a burden.
With obsessive-compulsive disorder, the worries that drive the condition are not trivial. It can be all-consuming and often irrational, so dismissing their concerns as “no big deal” can make them feel isolated, unheard, and misunderstood.
“I can see this is really troubling for you. Would it help to talk through it, or do you prefer to distract yourself with something else?”
Offering empathy and a potential strategy for coping with the anxiety and fear that comes with OCD helps minimize the panic. Oftentimes, it can help minimize the chances of analysis paralysis that follows a particularly stressful time.
Relaxing is a choice for some, but obsessive-compulsive disorder is a different condition altogether. Telling someone with OCD to “just relax” is dismissive and disheartening.
OCD often requires professional treatment, such as cognitive behavioral therapy (CBT), to manage symptoms effectively.
“I know it’s not easy to relax when you’re feeling this way. Can I help you feel more at ease when you’re going through this?”
By showing your understanding and inviting the person to share what helps them, you can help reinforce that their feelings are valid and their experience matters.
Supporting someone with OCD goes beyond knowing what to say and what not to say. It’s about understanding the nature of the disorder and recognizing that treatment can be a long and challenging process.
On average, it takes adults 14 to 17 years to receive an OCD diagnosis and effective treatment. This delay can contribute to prolonged suffering and an increased risk of developing other mental health issues, such as depression and anxiety.
Here’s how to help someone with OCD:
Whether you know someone or just want to be more aware, your efforts to understand those with OCD can make a meaningful difference in their lives. What you say matters, and your empathy can be a powerful tool in their journey living with OCD.
Pampaloni, I., Marriott, S., Pessina, E., Fisher, C., Govender, A., Mohamed, H., Chandler, A., Tyagi, H., Morris, L., & Pallanti, S. (2022). The global assessment of OCD. Comprehensive Psychiatry, 118, 152342. https://doi.org/10.1016/j.comppsych.2022.152342
Gillette, H., & Washington, N. (2022, July 14). OCD and indecision: Why making up your mind may be so difficult. Psych Central. https://psychcentral.com/ocd/ocd-indecision-symptom
Hezel, D. M., Rose, S. V., & Simpson, H. B. (2022). Delay to diagnosis in OCD. Journal of Obsessive-Compulsive and Related Disorders, 32, 100709. https://doi.org/10.1016/j.jocrd.2022.100709

Facebook-f X-twitter Youtube TLDR: Mental health conditions affect more than 1 in 5 U.S. adults, yet warning signs are frequently missed because they emerge gradually
Facebook-f X-twitter Youtube TLDR; ADHD is a brain-based disorder that is frequently misdiagnosed or undetected for years because its symptoms overlap with dozens of other
Headaches, a queasy stomach, muscle pain—is it time to reach for the aspirin or ibuprofen? Or is it anxiety or depression causing your symptoms?
Anxiety and depression are best known for causing mental distress—making you feel nervous, worried, sad, or numb. But these common mental health conditions—anxiety disorders affect an estimated 40 million Americans and major depressive disorder affects approximately 17 million—are also associated with a host of physical symptoms.
According to Amen Clinics, a global leader in brain health that has treated tens of thousands of people with mental health issues over the past 30-plus years, here are five of the most common physical signs of anxiety and depression.
Research has found that chronic daily headaches are common in people with clinical depression and anxiety, especially in people with generalized anxiety disorder or panic disorder.
Some people experience tension headaches that can cause mild to moderate pain and may involve stiffness in the neck and shoulders. Others suffer from migraine headaches, which are associated with more severe pain and can interfere with daily activities.
A 2018 study in the journal Headache found that people with frequent migraine headaches are more likely to experience anxiety and depression.
Muscle tension is often seen in people with anxiety disorders, such as panic disorder, and chronic pain is frequently seen in depressed people. Research in the Journal of the Neurological Sciences shows that people with depression tend to have a lower tolerance for pain.
At Amen Clinics, brain imaging studies using single photon emission computed tomography (SPECT) scans show that people who experience chronic pain often have too much activity in an area of the brain called the thalamus.
This brain region is part of the deep limbic system, which is the brain’s emotional centers. On brain scans, overactivity in the limbic system is often associated with depression. This suggests that chronic pain and depression may activate the same brain systems.
Everyone knows that anxiety about a big life event can trigger a nervous stomach, but the connection between the digestive tract and mental health goes even deeper. Feeling nauseous, having stomach cramps, or experiencing constipation or diarrhea are all associated with anxiety and depression.
Findings from a study appearing in Advanced Biomedical Research showed that people with irritable bowel syndrome (IBS) have higher anxiety and depression symptoms compared with people who don’t have IBS.
Researchers have also found that people with anxiety or mood disorders are more likely to have constipation compared with the general population.
When you have anxiety, you may worry incessantly, which can be exhausting. Similarly, having depression is strongly linked to fatigue. Being depressed can lead to a physical lethargy, a sense of apathy, and a loss of mental energy.
However, the fatigue you feel may also be related to sleep troubles. Anxious thoughts may make it difficult to fall asleep or may cause you to wake up in the middle of the night when worries start spinning in your mind. According to scientific evidence, over half of all people with anxiety have trouble sleeping.
Depression and poor sleep also go hand in hand. Research in Dialogues in Clinical Neuroscience shows that about 75% of people with depression also have insomnia. Early awakening is also common among depressed people.
A smaller percentage of people with depression sleep more than usual but still feel daytime sleepiness. If you aren’t sleeping well, get an evaluation before taking sleeping pills, which may be hard to stop.
Feeling your heart start to race or experiencing tightness in the chest can be symptoms of panic attacks. After the panic attack subsides, heart rate usually returns to normal levels and any chest pain goes away.
In some people with depression or anxiety, however, chest pain can become chronic. A 2023 study explores the bidirectional relationship between heart disease and depression and anxiety.
According to this study, the prevalence of people with depression who have cardiovascular disease is 20%–40%, far higher than the rate among healthy individuals. At the same time, people with heart disease are more likely to develop depression compared to the general population.
These findings also indicate that people with cardiovascular disease are more likely to have anxiety. In fact, they have a 26% increased risk of anxiety.
Because of this, if you’re experiencing any form of chest pain, it’s critical to see a doctor to determine what’s causing it.
You may not realize that the recurring aches and pains, digestive issues, or fatigue you experience are related to mental health problems. Many people simply head to their primary care physician or another traditional medical professional in an effort to treat the physical issues without considering the possibility of underlying anxiety and depression.
However, this can lead to treatments that don’t solve the underlying issue. For example, taking medication for physical symptoms without treating the anxiety and depression won’t provide the lasting relief you want. Getting to the root cause of your physical symptoms is the key to feeling better.
To help you understand what’s causing your issues, pay attention to when your physical symptoms arise. Is it during times of increased stress, nervousness, or sadness?
Becoming aware of an increase in pain, more frequent headaches, or an uptick in digestive problems or other physical symptoms may be a clue that anxiety or depression may be to blame.
If you aren’t getting relief, it may be time to seek help from a mental health professional who understands the connection between the brain, body, and mind.
Getting a brain SPECT scan allows psychiatrists to identify brain activity patterns associated with anxiety and depression, as well as other brain and mental health issues. With a more accurate diagnosis, you’ll be on your way more quickly to feeling better both mentally and physically.
Wei, Cui-Bai et al. “Overlap between Headache, Depression, and Anxiety in General Neurological Clinics: A Cross-sectional Study.” Chinese Medical Journal vol. 129,12 (2016): 1394-9. doi:10.4103/0366-6999.183410
Chu HT, Liang CS, Lee JT, et al. “Associations Between Depression/Anxiety, Headache Frequency In Migraineurs: A Cross-Sectional Study.” Headache. 2018, 58(3):407-415. doi: 10.1111/head.13215.
Zambito Marsala, Sandro et al. “Pain perception in major depressive disorder: a neurophysiological case-control study.” Journal of the neurological sciences vol. 357,1-2 (2015): 19-21. doi:10.1016/j.jns.2015.06.051
Roohafza, Hamidreza et al. “Anxiety, depression and distress among irritable bowel syndrome and their subtypes: An epidemiological population based study.” Advanced biomedical research vol. 5 183. 28 Nov. 2016, doi:10.4103/2277-9175.190938
Hosseinzadeh, Sahar Tahbaz et al. “Psychological disorders in patients with chronic constipation.” Gastroenterology and hepatology from bed to bench vol. 4,3 (2011): 159-63.
Nutt, David et al. “Sleep disorders as core symptoms of depression.” Dialogues in clinical neuroscience vol. 10,3 (2008): 329-36. doi:10.31887/DCNS.2008.10.3/dnutt
Harvard Health Publishing. “Sleep deprivation can affect your mental health,” August 17, 2021, https://www.health.harvard.edu/newsletter_article/sleep-and-mental-health
Li, Xinzhong et al. “Cardiovascular disease and depression: a narrative review.” Frontiers in cardiovascular medicine vol. 10 1274595. 21 Nov. 2023, doi:10.3389/fcvm.2023.1274595

Facebook-f X-twitter Youtube TLDR: Mental health conditions affect more than 1 in 5 U.S. adults, yet warning signs are frequently missed because they emerge gradually
Facebook-f X-twitter Youtube TLDR; ADHD is a brain-based disorder that is frequently misdiagnosed or undetected for years because its symptoms overlap with dozens of other
As the most complex organ in the universe, the human brain is a miraculous system. It contains 100,000 miles of blood vessels and 100 billion neurons that connect to trillions of other cells in the body.
The brain is also incredibly powerful, active, and hard-working. It processes information at lightning-fast speeds. In fact, on an average day, a human being will have roughly 70,000 thoughts, comprised of both words and images.
With this kind of activity occurring around the clock, it’s important to consciously build downtime into our days. While we may not be able to (or want to) stop our brains from working altogether, regularly scheduling cognitive rest helps prevent the anxiety and fatigue that are byproducts of a stressed brain.
In other words, it’s time to give your brain a break!
Why take a brain break? Let’s look at some influences that are contributing to Americans’ constant brain overload—and the many benefits of scaling back.
While we should all marvel at the brain’s incredible capabilities, they can also feel like they’re working against us. Many people have experienced, for example, racing thoughts that keep them awake at night. Others might fill their brains with so much information, like when cramming for an exam, that they end up feeling anxious, stressed, and exhausted.
Unfortunately, simply living in our modern world can also lead to information overload. Seemingly basic tasks like scrolling through email or social media pages require significant amounts of brain processing every second. This only compounds with damaging habits like multiple-screen usage when trying to “multitask.”
In a 2019 scientific review that examined how the internet may be changing our cognition, researchers determined that frequent online exposure may influence:
The review explained that each of these changes related to Internet usage can be both acute and sustained (that is, short-term and long-term). They may even trigger physical changes in the brain.
Under the pressures of a 24/7 onslaught of information (exacerbated by mobile devices), many people believe they can’t take a break. There’s always something to consume, visually and/or aurally—and, over time, people can start to feel uncomfortable without constant stimulation. That can translate into always feeling like there’s more to do, and not enough time to do it.
But we know that constant, sustained activity can create stress in the body, which accelerates aging. A 2020 study published in Biomedicines noted that chronic stress is associated with:
To look, feel, and perform better well into your advanced years, reducing mental overload—and therefore brain stress—is a helpful strategy that you can adopt right now.
While people may believe that constant movement or stimulation is maximizing their productivity, studies have shown that it does the opposite. Taking micro-breaks throughout the day prevents a stressed brain and has been correlated with better attention and performance.
In one study, published in the journal Cognition, researchers found that brief breaks at work, especially on larger projects, improves focus. That’s because breaks prevent the brain from reaching an “autopilot” state that corresponds to paying less attention.
Another systematic review and meta-analysis of 22 studies on micro-breaks found that they boosted vigor and reduced fatigue. And “the longer the break, the greater the boost was on performance,” the researchers noted. While data supported micro-breaks as helpful for well-being, they found that “highly depleting tasks” would benefit from breaks longer than 10 minutes to promote optimal performance.
You’ve probably heard successful people claim—or experienced it for yourself—that their best ideas come to them in the shower. This time of quiet and solitude, performing routine tasks that require little brainpower, allows the mind to wander.
A study in the journal Science reported that during this “wandering,” your brain’s prefrontal cortex (PFC) gets a much-needed break. The PFC is in charge of complex mental tasks, including problem solving, focus, organization, and impulse control.
Similarly, so-called “boredom,” which many people rarely allow themselves nowadays, also has numerous benefits, including:
Finally, taking short breaks was found to help the brain when learning a new skill, according to a study by the National Institutes of Health. After performing a task like playing the piano or practicing a new language, taking a break allows the brain to replay it, which helps compress and consolidate those memories.
If you need some brain relaxation and don’t know where to begin, start small. Try any one of these suggestions, even in small doses, to grab some much-needed cognitive rest throughout your day:
And any exercise, from a 5-minute stretching session to heart-pumping cardio or weight training, offers a long list of benefits for the brain and entire body, including improvements for mental health.
In a study of adults with type 1 diabetes, taking time for daily play was associated with improvements in mood and greater ability to cope with stressors. Fun and games, such as working on jigsaw puzzles, can also keep your brain pleasantly active while not stressing it out.
Start by replacing 30 minutes or 1 hour of TV, computer, or smartphone time with an “analog” activity like inspirational reading, meditation, or daydreaming outside while watching the clouds. This time slot can be enjoyed in a single session or spaced out in smaller increments throughout your day.
It’s easy to get sucked into the false promises of constant “productivity” or the online content consumption that’s increasingly crowding our world—and our brains. But your brain needs a rest.
Instead of looking at life like a never-ending to-do list, take the time to pause throughout your day. Even a few minutes every hour, or 1 hour in the morning and evening, can help promote mental calm and clarity, supporting the rested brain you need.
Firth J, Torous J, Stubbs B, Firth JA, Steiner GZ, Smith L, Alvarez-Jimenez M, Gleeson J, Vancampfort D, Armitage CJ, Sarris J. The “online brain”: how the Internet may be changing our cognition. World Psychiatry. 2019 Jun;18(2):119-129. doi: 10.1002/wps.20617. PMID: 31059635; PMCID: PMC6502424.
Yegorov YE, Poznyak AV, Nikiforov NG, Sobenin IA, Orekhov AN. The Link between Chronic Stress and Accelerated Aging. Biomedicines. 2020 Jul 7;8(7):198. doi: 10.3390/biomedicines8070198. PMID: 32645916; PMCID: PMC7400286.
Atsunori Ariga, Alejandro Lleras, Brief and rare mental “breaks” keep you focused: Deactivation and reactivation of task goals preempt vigilance decrements, Cognition, Volume 118, Issue 3, 2011, Pages 439-443, ISSN 0010-0277, https://doi.org/10.1016/j.cognition.2010.12.007. (https://www.sciencedirect.com/science/article/pii/S0010027710002994)
Albulescu P, Macsinga I, Rusu A, Sulea C, Bodnaru A, Tulbure BT. “Give me a break!” A systematic review and meta-analysis on the efficacy of micro-breaks for increasing well-being and performance. PLoS One. 2022 Aug 31;17(8):e0272460. doi: 10.1371/journal.pone.0272460. PMID: 36044424; PMCID: PMC9432722.
National Institutes of Health, Study shows how taking short breaks may help our brains learn new skills, https://www.nih.gov/news-events/news-releases/study-shows-how-taking-short-breaks-may-help-our-brains-learn-new-skills
Sleep Health, Is there an association between daytime napping, cognitive function, and brain volume? A Mendelian randomization study in the UK Biobank, by Valentina Paz, Msc, Hassan S. Dashti, PhD, Victoria Garfield, PhD. DOI: https://doi.org/10.1016/j.sleh.2023.05.002
Malia F. Mason et al. Wandering Minds: The Default Network and Stimulus-Independent Thought. Science 315, 393-395 (2007). DOI: 10.1126/science.1131295
Van Vleet M, Helgeson VS, Berg CA. The importance of having fun: Daily play among adults with type 1 diabetes. J Soc Pers Relat. 2019 Nov 1;36(11-12):3695-3710. doi: 10.1177/0265407519832115. Epub 2019 Mar 6. PMID: 34054178; PMCID: PMC8158911

Facebook-f X-twitter Youtube TLDR: Mental health conditions affect more than 1 in 5 U.S. adults, yet warning signs are frequently missed because they emerge gradually
Facebook-f X-twitter Youtube TLDR; ADHD is a brain-based disorder that is frequently misdiagnosed or undetected for years because its symptoms overlap with dozens of other
Bipolar disorder is in the spotlight these days thanks to several celebrities—including Kanye West, Demi Lovato, Bebe Rexha, and Halsey—who have gone public with their diagnoses. These high-profile individuals are among the 5.7 million Americans affected by bipolar disorder.
While this has helped spread awareness about the mental health condition, there’s one important aspect of bipolar disorder that rarely gets mentioned—the brain. Ignoring the brain when this condition is suspected can lead to misdiagnosis, the wrong treatment, and years of needless suffering.
Here’s what you need to know about this brain-based disorder.
Bipolar disorder is a cyclic mood disorder, shifting between manic episodes and depressive episodes that are characterized by severe changes in mood, energy, and activity levels. The recent discussions in the media and on social media have brought to light some of the most common bipolar disorder symptoms.
For example, manic episodes are characterized by:
On the other end of the spectrum, depressive episodes are associated with:
Note that you may not experience all of these symptoms of bipolar disorder. In addition, symptoms of mania and depression can range in severity.
Experts have identified multiple types of bipolar disease, including:
Bipolar 2 disorder (also known as bipolar II)”:
Individuals with this type typically experience both emotional highs and low moods in a cyclical pattern. However, the key distinction between these types of the disorder is that the elevated mood episodes in bipolar 2 are less intense than those in bipolar 1 and do not reach the level of full-blown mania. These episodes in bipolar 2 are referred to by mental health professionals as “hypomanic.”
Bipolar 1 and bipolar 2 are the most common types of the condition. Knowing which type you have is critical to getting the most effective treatment.
A growing body of neuroimaging research shows that people with bipolar disorder tend to have abnormal activity patterns in the brain. For example, one study on brain function in bipolar disorder revealed deficits in a trio of areas:
Functional brain scans suggest that the underlying pathophysiology involves widespread neural circuits, including the prefrontal cortex and anterior cingulate cortex, as well as limbic system regions like the amygdala and ventral striatum.
Functional imaging of people during a manic episode has revealed abnormal changes in blood flow and metabolism, especially in the orbitofrontal cortex.
For over 30 years, Amen Clinics has been utilizing a brain imaging technology called single photoemission computed tomography (SPECT), which measures blood flow and activity.
For the patients at Amen Clinics and their families, seeing their brain scans helps them understand that symptoms and behaviors associated with bipolar disorder are not “mental disorders” or character flaws, rather, they’re “brain health” problems.
Unfortunately, millions of people in America who are suffering from bipolar disorder and other mental health issues don’t get the help they need due to the stigma surrounding mental health.
Reframing the discussion from mental health to brain health helps overcome that stigma because it shows that conditions are not moral, they’re medical.
For Amen Clinics patients with bipolar disorder, brain imaging has also revealed some surprising findings. For example, SPECT scans show that many people who are diagnosed with bipolar disorder also have an underlying concussion or traumatic brain injury that has never been properly diagnosed or treated.
Many of these people don’t even remember experiencing a head injury. This hidden trauma can be the result of one or more head injuries that happened months, years, or even decades earlier.
Some of the most common causes include falls (falling off a bike, falling off a ladder, or falling down a flight of stairs), vehicle accidents, or sports-related concussions. Having a brain injury can exacerbate the ups and downs of bipolar disorder.
SPECT scans can also help detect other mental health conditions that commonly co-occur with bipolar disorder. For example, research in Clinical Psychology shows that 62% of people with bipolar disorder also meet the clinical criteria for attention deficit hyperactivity disorder (ADHD), also called attention deficit disorder (ADD). Anxiety disorders and substance use disorders are also common in people with bipolar disorder.
Addressing co-existing mental health problems is a critical aspect of bipolar disorder treatment. Only when all issues are treated can you get the relief you want.
Without the added help of brain imaging, bipolar disorder is often misdiagnosed for other conditions, such as depression or schizophrenia.
In fact, most people experience signs of bipolar disorder for an entire decade before getting an accurate diagnosis. This can have devastating effects because following the wrong treatment plan can make symptoms worse.
When left untreated or mistreated, the condition is associated with a decrease of over 9 years in life expectancy. In addition, people with bipolar disorder are 15 times more likely to attempt suicide than the general population, and 1 in 5 people with the condition eventually take their own life.
Bipolar disorder is treatable. It is generally responsive to a treatment program that is personalized to enhance brain health and that may include:
The patient population at Amen Clinics shows that healing the brain can be very helpful in reducing symptoms associated with bipolar disorder.
Youngstrom, Eric A et al. “Bipolar and ADHD Comorbidity: Both Artifact and Outgrowth of Shared Mechanisms.” Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association vol. 17,4 (2010): 350-359. doi:10.1111/j.1468-2850.2010.01226.x
Clark, Luke, and Barbara J Sahakian. “Cognitive neuroscience and brain imaging in bipolar disorder.” Dialogues in clinical neuroscience vol. 10,2 (2008): 153-63. doi:10.31887/DCNS.2008.10.2/lclark

Facebook-f X-twitter Youtube TLDR: Mental health conditions affect more than 1 in 5 U.S. adults, yet warning signs are frequently missed because they emerge gradually
Facebook-f X-twitter Youtube TLDR; ADHD is a brain-based disorder that is frequently misdiagnosed or undetected for years because its symptoms overlap with dozens of other
Is someone in your life continually dismissing your feelings or belittling you, insisting you’re too sensitive or that you overreact to everything? Does this individual cause you to doubt your perceptions, even what you know to be true? Have you stopped confronting this person because they continually shift blame, respond angrily, deny, or lie when you do?
If you’re experiencing even one of these scenarios, it’s possible you’re being gaslit.
As the term gaslighting is over misused and misunderstood, here’s a clear description of what it is and subtle signs to help you identify the behavior.
Simply put, gaslighting is a form of psychological manipulation in which a person (or sometimes an entity) makes a victim question their reality in order to gain more power or control. It is a mentally abusive pattern of behavior that, over time, can cause depression, anxiety, and low self-esteem in the victim.
It happens most often in romantic relationships, but it can also occur in friendships, work relationships, and families. It can also arise in any kind of situation where an individual places trust in an authority figure, such as with a doctor or cult leaders.
A gaslighter/abuser deliberately and systematically feeds false information to their victim, which leads them to question what they know to be true. The gaslighter does this in subtle ways over time, making it hard to detect, much like a slow boil.
Gradually, the victim starts to doubt their perceptions, feelings, memories, and even their sense of reality. They lose their self-confidence and may even start to doubt their sanity. They begin to think they are the problem. All of this serves to make them more dependent on the gaslighter.
Abusers use gaslighting to gain control or power over another individual, as well as to avoid accountability. While it’s usually deliberate, some people may be unaware of what they are doing.
Individuals with mental health conditions, such as narcissistic personality disorder, antisocial personality disorder, and borderline personality disorder are prone to exhibit gaslighting behavior. Others may have grown up in families where gaslighting was normalized.
While this form of emotional abuse can happen to anyone, women are more likely to be victims of gaslighting. In romantic relationships, it may lead to domestic abuse. One study titled “The Sociology of Gaslighting” makes the case that abusers use the cultural bias of women being irrational to their advantage.
Here are 10 subtle signs of gaslighting gathered from more than 30 years of clinical practice at Amen Clinics, research, and the results from a 2023 qualitative research study on gaslighting in romantic relationships:
Gaslighters want to sow seeds of doubt in your own perceptions. They do this by telling blatant lies and denying them when confronted—even when confronted with proof of their lying.
They may say, “I never said that.” That’s because if they tell you a huge lie, you begin to wonder if anything they say is true. It teaches you that you cannot trust your senses.
The more they lie and deny, the more you question your own reality and start accepting the one they present.
A gaslighter will accuse you of the very things they are doing, projecting their negative character traits and behavior onto you. They may accuse you of dishonest, manipulative behavior (as they are typically dishonest and manipulative).
This places you in a position of defending your own honest motivations, which causes you to start doubting your own intentions. It also distracts from their own deceptive behavior.
Gaslighters love to say things like “calm down” or “chill out.” They will tell you that you’re overreacting or being overemotional, especially if you call them out on something or hold them accountable for their actions.
This dismissive behavior invalidates your genuine feelings and diminishes your self-worth, making you more dependent on their approval.
These psychological manipulators are experts at making everything your fault, especially by shifting blame onto you. For example, they deflect instead of taking responsibility for their actions by claiming if you acted differently, they would not treat you as they do.
So, it’s your fault! They’ll also say things like, “You made me do this.” Or they may say, “You’re the one causing problems.” This may lead you to feel guilty or have self-doubt.
Gaslighters are masterful at finding people who will stand with them against you. They may spread rumors about you. And then they’ll come back and tell you other people are against you. They might say a particular person agrees with them.
They may lie and tell you a disparaging remark someone else said (even though they didn’t say it). This manipulative tactic makes you doubt who you can trust, and it leaves you more isolated and dependent on the gaslighter. Ultimately, that’s what they want.
People who exhibit gaslighting behavior might appear impressively confident or strong in their convictions initially. It is neither, but instead their need to be right.
In healthy relationships, there are two perspectives in any disagreement. But gaslighters insist that their perspective is the correct one, the only truth.
Gaslighters don’t like you having power or attention. They will undermine your accomplishments with veiled compliments or outright criticism. “It wasn’t that difficult” or “Most people could do that” are examples of this.
These types of cruel comments serve the gaslighter by causing you to second-guess yourself and perhaps even agree with them. Over time, comments like these erode your self-esteem and confidence. This makes you more reliant on the manipulator for approval.
To create confusion and make it harder to discern their critical words, controlling behavior, and lies, gaslighters will offer up praise for something you did. They do this just enough to make you feel confused and keep you guessing about them. It creates uneasiness and confusion to receive compliments from the individual who usually belittles you. That’s what they want.
You may think, “Oh, they aren’t so bad.” It’s an attempt to keep you questioning and doubting your own perceptions—to keep you off kilter. You may think you’re just being oversensitive when they’re being critical. Oftentimes, when they praise you, it usually benefits them in some way.
Gaslighters might start off wanting to spend loads of time with you. It might feel great. They are notorious love bombers. But then they start to discourage you from talking to and spending time with friends and family. They may even suggest the relationships are not good for you.
When you’re isolated from other loved ones, they make you more dependent on them for your social needs, giving them more control and ability to manipulate you. Without access to feedback from your circle of family and friends, the gaslighter can avoid accountability for bad behavior. Social isolation can also make you feel diminished and like you are losing your grip on reality.
A gaslighter will refuse to listen to you if you confront them about a lie or their behavior. Sometimes they will change the subject or pretend like they don’t understand what you’re saying.
They may say something like, “That doesn’t make any sense” or “Are you sure you know what you’re talking about?” Like so many of their behaviors, this results in self-doubt. It may cause uneasiness too.
If you suspect that you’re experiencing gaslighting, reach out to a qualified mental health professional. They can help you overcome feelings of anxiety and depression associated with being gaslit. They can also provide you with helpful strategies so you can learn to take care of yourself, set boundaries, potentially end the relationship, and recover your well-being.
If you’re in a situation of domestic abuse, call the National Domestic Violence Hotline 24/7 at 800-799-7233.
Sweet, P. L. (2019). The sociology of gaslighting. American Sociological Review, 84(5), 851–875. https://doi.org/10.1177/0003122419874843
March, E., Kay, C. S., Dinić, B. M., Wagstaff, D., Grabovac, B., & Jonason, P. K. (2023). “it’s all in your head”: Personality traits and gaslighting tactics in intimate relationships. Journal of Family Violence. Advance online publication. https://doi.org/10.1007/s10896-023-00582-y
Willis K, Li S, Wood S. “A qualitative analysis of gaslighting in romantic relationship.” Personal Relationships. 2023 Dec;30(4):1316-1340

Facebook-f X-twitter Youtube TLDR: Mental health conditions affect more than 1 in 5 U.S. adults, yet warning signs are frequently missed because they emerge gradually
Facebook-f X-twitter Youtube TLDR; ADHD is a brain-based disorder that is frequently misdiagnosed or undetected for years because its symptoms overlap with dozens of other
These days, people talk about marijuana, pot, weed, or cannabis as a natural health remedy for issues like chronic pain, nausea, and anxiety. But this controversial substance, which is revered by some for its calming effects, comes with a host of side effects, especially in adolescents and teens.
Mounting research shows that cannabis use leads to significant impacts on the developing brain. And they aren’t good.
In this blog, you’ll discover the scary ways cannabis use alters human brain function. And how these changes can have lifelong consequences.
With so much information about cannabis coming at you from news sources, social media, and health professionals, it can be challenging to know fact from fiction. However, a wealth of emerging science is helping clear up the cannabis confusion.
To simplify things, understand that cannabis is comprised of over 120 components called cannabinoids. Two of the most well-researched cannabinoids are cannabidiol (CBD) and tetrahydrocannabinol (THC).
The endocannabinoid system plays a crucial role in brain development, including synaptic pruning, neurogenesis, and the regulation of neurotransmitter release. This system includes cannabinoid receptors (CB1 and CB2), endogenous cannabinoids (endocannabinoids like anandamide and 2-AG), and enzymes for their synthesis and degradation.
THC, the psychoactive component of marijuana, binds to CB1 receptors, leading to altered endocannabinoid signaling. During adolescence, the ECS is especially active and critical for proper brain maturation. Research suggests that disruption by exogenous cannabinoids can interfere with these processes.
In the developing brain, several important processes occur during adolescence. Using marijuana may interfere with this critical phase.
The hippocampus, a region critical for learning and memory, continues to generate new neurons throughout life. Chronic THC exposure can reduce hippocampal neurogenesis, leading to memory deficits and cognitive decline, according to a study in Translational Psychiatry.
Neurotransmitters are the chemical messengers used by the nervous system to allow neurons to communicate with each other or other part of the body. Because these neurochemicals transmit information between the brain and body, they are critically important to overall health and well-being. Specific neurotransmitter systems that are affected by marijuana use include the dopaminergic, glutaminergic, and GABAergic systems.
The prefrontal cortex (PFC), responsible for executive functions such as decision-making, planning, and impulse control, is one of the last brain regions to mature. THC exposure during adolescence can alter the development of the PFC, leading to long-term deficits in these functions.
The hippocampus is particularly vulnerable to THC due to its high density of CB1 receptors.
As you can see from this blog, the science on cannabis use during adolescence strongly indicates that it interferes with healthy brain development and leads to lasting consequences. If your teenager is using marijuana regularly, it’s important to seek help from a mental health professional or a specialist in addiction treatment.
The earlier adolescents get help and stop using cannabis, the better for their brain. And with a better brain, they will have a better life.
Dr. Rishi Sood is Associate Medical Director of Amen Clinics Inc. and a child and adult psychiatrist.
Reviewed by Amen Clinics Inc. Clinicians
Jacobus, Joanna, and Susan F Tapert. “Effects of cannabis on the adolescent brain.” Current pharmaceutical design vol. 20,13 (2014): 2186-93. doi:10.2174/13816128113199990426
Bara, Anissa et al. “Cannabis and synaptic reprogramming of the developing brain.” Nature reviews. Neuroscience vol. 22,7 (2021): 423-438. doi:10.1038/s41583-021-00465-5
Misner, D L, and J M Sullivan. “Mechanism of cannabinoid effects on long-term potentiation and depression in hippocampal CA1 neurons.” The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 19,16 (1999): 6795-805. doi:10.1523/JNEUROSCI.19-16-06795.1999
Yücel, M et al. “Hippocampal harms, protection and recovery following regular cannabis use.” Translational psychiatry vol. 6,1 e710. 12 Jan. 2016, doi:10.1038/tp.2015.201
Bloomfield, Michael A P et al. “The effects of Δ9-tetrahydrocannabinol on the dopamine system.” Nature vol. 539,7629 (2016): 369-377. doi:10.1038/nature20153
Colizzi, Marco et al. “Effect of cannabis on glutamate signalling in the brain: A systematic review of human and animal evidence.” Neuroscience and Biobehavioral Reviews vol. 64 (2016): 359-81. doi:10.1016/j.neubiorev.2016.03.010
Orr C, et al. “Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence.” Journal of Neuroscience (2019), 39(10): 1817-1827; DOI: 10.1523/JNEUROSCI.3375-17.2018
Colyer-Patel, K., Romein, C., Kuhns, L. et al. Recent Evidence on the Relation Between Cannabis Use, Brain Structure, and Function: Highlights and Challenges. Curr Addict Rep 11, 371–383 (2024). https://doi.org/10.1007/s40429-024-00557-z
Jackson NJ, et al. “Impact of adolescent marijuana use on intelligence: Results from two longitudinal twin studies.” PNAS, 113 (5) E500-E508 (2016). https://doi.org/10.1073/pnas.1516648113

Facebook-f X-twitter Youtube TLDR: Mental health conditions affect more than 1 in 5 U.S. adults, yet warning signs are frequently missed because they emerge gradually
Facebook-f X-twitter Youtube TLDR; ADHD is a brain-based disorder that is frequently misdiagnosed or undetected for years because its symptoms overlap with dozens of other
Wondering why you feel depressed, anxious, or unfocused? Take a hard look at your diet. Experts are increasingly linking the foods you eat to your mental health.
For example, in a 2020 study in The BMJ the lead authors stated, “Poor nutrition may be a causal factor in the experience of low mood, and improving diet may help to protect not only the physical health but also the mental health of the population.” In other words, food matters when it comes to mental health.
Unfortunately, many foods and food ingredients that are common in the standard American diet are toxic to your mental well-being. They can harm your brain, and put you at increased risk for brain health problems and mental health conditions such as:
In this blog, you’ll discover the research behind six common toxic foods showing how they increase mental health problems. Plus, you’ll learn some simple detox tips to reduce your intake of toxic foods to boost brainpower and mental strength.
Often when we feel bad, we crave sugary sweetness. We love the comfort sweet foods provide, but they don’t love us back.
Sugar (and even natural honey and maple syrup), as well as refined carbohydrates (white bread, pastries, pasta, and crackers), cause blood sugar levels to spike and then drop, impacting your mood and sense of wellbeing.
Diets high in sugar increase inflammation, cause fatigue and cravings, and lead to erratic brain cell firing that has been implicated in aggression, a 2021 study indicates. Another recent study showed increased markers of preclinical Alzheimer’s disease (lower overall brain and hippocampal volume, poorer episodic memory, and cognitive decline) associated with regular consumption of sugary beverages.
Detox tip: Read labels carefully to avoid added sugars and beware of the many alternative names for sugar used on food labels.
While fish is normally a very healthy food, some types of fish are very high in mercury and should be avoided. Mercury, a known neurotoxin, makes its way up the food chain and can collect in harmful amounts in top predatory fish.
Mercury can damage the brain and nerves. A study published in 2017 found an association with mercury exposure and neurological distress, mood changes, and difficulty regulating emotions, as well as gastrointestinal disruptions.
Inflammation in the gut is directly linked to central nervous system disruption and mental health issues including anxiety and depression, according to research.
Because of their high mercury content, king mackerel, shark, swordfish and tilefish are on the “do not eat” list created by the U.S. Food and Drug Administration and the Environmental Protection Agency.
Detox tip: Avoid high-mercury fish and eat fish that are lower in mercury, such as anchovies, Atlantic mackerel, salmon, sardines, and trout.
Surprisingly, artificial sweeteners—including aspartame (NutraSweet, Equal), saccharine (Sweet’N Low), and sucralose (Splenda)—can lead to chronically elevated insulin levels, according to studies. This raises your risk of depression, Alzheimer’s disease, heart disease, diabetes, and other health problems.
Research shows that artificial sweeteners have also been associated with metabolic syndrome and may contribute to obesity, both of which can play a role in mental health issues.
Aspartame appears to be particularly egregious as research has separately linked it to behavioral and cognitive problems, as well as neurophysiological symptoms such as learning problems, headache, seizure, migraines, irritable moods, anxiety, depression, and insomnia.
Additionally, for people with chronic digestive inflammatory disorders, evidence suggests that artificial sweeteners may induce pro-inflammatory changes in gut bacteria and gut wall immune reactivity. As mentioned above, this can play a role in depression, anxiety. and other mental health disorders.
Detox tip: Skip artificial sweeteners and go for natural sweeteners, such as stevia, that don’t impact insulin levels.
While fruits and vegetable are critical to vibrant health, some conventionally grown produce is tainted with pesticide residue, which can negatively impact mental health.
According to testing conducted by the Environmental Working Group, the most pesticide-laden fruits and veggies for 2024 (known as the “Dirty Dozen”) include:
One recent study suggests that low levels of pesticide exposure can affect young children’s neurological and behavioral development, showing a link between pesticides and neonatal reflexes, psychomotor and mental development, and ADHD.
Detox tip: Eat organic produce whenever possible.
MSG may be an FDA-approved flavor enhancer, but it is also a type of excitatory neurotoxin (excitotoxin) that has been shown to adversely affect the brain. It is required to be noted as an ingredient on food labels, but it often goes undetected when it is listed as:
What are excitotoxins? They are substances, usually amino acids, that overstimulate neuron receptors. Upon excitotoxin exposure, neurons fire more rapidly than normal. This process, if prolonged, can exhaust and weaken neurons, resulting in neuronal death.
Don’t underestimate their effects. The electrical activity from excitotoxins like MSG can change the activity of the brain and can be associated with temper outbursts, depression, suicidal thoughts, panic attacks, distractibility, and confusion.
Detox tip: Avoid foods containing MSG and learn the alternate names used for this substance so you can detect its presence on food labels.
Gluten is the general name given for the proteins found in wheat, rye, barley, and triticale (a cross between wheat and rye) and is increasingly a problem for people who have a sensitivity to it.
The Center for Celiac research reports that approximately 18 million Americans have gluten sensitivity. It is associated with autoimmune conditions such as celiac disease, type 1 diabetes, and Hashimoto’s thyroiditis.
One review study found that gluten sensitivity and celiac disease are related to a number of brain health/mental health issues, including:
Scientific evidence shows that a gluten-free diet has been associated with improvements in people who have mental health conditions. Specifically, one study found a decrease of symptoms in a set of patients with schizophrenia. And going gluten-free produced a decrease in symptoms in some people in a study on autism, research on ADD/ADHD, and a review study on depression.
Detox tip: Try giving up gluten for 30 days. Notice any changes in how you feel physically and mentally. Then add it back into your diet and take note of any symptoms that arise. If you do experience symptoms, you may want to consider switching to a gluten-free diet on a permanent basis.
While we’ve highlighted a few toxic foods for mental health, there are more, and this field of examination is evolving. Foods that produce allergic reactions such as soy, corn, and milk products may increase mental health problems. Other food additives, such as Red Dye #40, have been shown to have negative effects.
Stay informed, read labels, and pay attention to how you feel. Importantly, choose brain healthy foods on a regular basis to improve brainpower and mental strength.
Reviewed by Amen Clinics Inc. Clinicians
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In generations past, young people were traditionally associated with hard-partying lifestyles. But when it comes to drinking alcohol, it’s the baby boomer generation (born 1946-1964) whose consumption may pose the biggest problem in years to come.
After all, the combination of a large aging population and their reportedly increasing alcohol use could take a serious toll. It can affect everything from our nation’s healthcare system to family members and caregivers. And for the older adults themselves, this mixture can turn destructive or even deadly.
As Gen Z increasingly says no to alcohol consumption or joins the sober curious movement, adults 65 and older may be moving in the opposite direction. Baby boomers are showing rising levels of both alcohol consumption and alcohol use disorder (AUD), according to a 2023 article published in the medical journal Alcohol.
American Addiction Centers confirms that alcohol use among adults over 65—including problematic drinking behaviors—is on the rise. Here are some stats the organization shares:
While alcohol is a toxic substance at any age, drinking can lead to more dangerous effects among the over-65 population. Let’s explore the numerous factors that make alcohol consumption especially problematic for older adults.
Both aging and alcohol affect all systems of the body, and the human brain is no exception. Alcohol abuse has been associated with brain damage, especially in brain regions such as the prefrontal cortex (PFC) and hippocampus.
Because the PFC is involved with decision-making and the hippocampus impacts memory and mood, alcohol use may ultimately promote more alcohol use. Less impulse control combined with low moods makes it easier to get caught in a cycle that leads to abuse and addiction.
In addition, heavy alcohol use lowers blood flow to the brain and therefore has been linked to lower neurogenesis, or the generation of new brain cells. Research has shown that drinking even “moderate” amounts of alcohol (1-7 drinks per week) is associated with lower total brain volume, with heavier use leading to greater shrinkage.
It’s no surprise that, according to one study, moderate to heavy drinkers have a 57% higher risk of dementia than non-drinkers and light drinkers. And alcohol abuse has been determined as a driver of accelerated brain aging.
The process of aging, on the other hand, is commonly accompanied by symptoms of cognitive decline. Adding ongoing alcohol use to the brain’s normal aging process can be devastating.
Many people experience changes in their slumber as they age, such as interrupted sleep and reduced quality or quantity of sleep. The Sleep Foundation points to various factors behind these disruptions, including:
As a notorious sleep destroyer, alcohol only worsens these issues. Drinking booze before bed is linked to dysfunctional sleep patterns, lower-quality sleep due to REM sleep disruptions, and even snoring and sleep apnea. Furthermore, sleep issues like insomnia can wreak havoc on both cognitive performance and mental health.
As reflexes and muscle mass decline and other health issues may impede movement, the elderly are at high risk for falls. The National Institute on Aging (NIA) reports that more than one-quarter of people ages 65 or older fall each year, and their risk only rises with age.
Falls must be taken more seriously in the elderly, because they can lead to broken bones, hospital visits, disability, and even death. But anyone who’s taken a drink knows that alcohol interferes with major functions like coordination, stability, balance, and judgment. These all increase fall risk.
In addition, one study found that those who consumed alcohol were more likely to sustain a head injury during a fall than those who had not drank. The alcohol users were also at risk for more severe injuries, with more alcohol consumption associated with greater severity.
Falls are just one major concern when drinking. The risk of other (and potentially deadly) injuries also increases, such as those caused by car accidents, fires, domestic violence, drowning, or hypothermia.
A 2023 review in Molecular Metabolism noted that “evidence suggests a bidirectional and cyclical relationship between chronic inflammation and the development of age-related conditions” like cardiovascular diseases, neurodegeneration, and general frailty.
Indeed, inflammation has been linked to everything from memory loss and mental health issues to liver disease and arthritis. We also know that drinking alcohol creates inflammation in the body. And the development of chronic diseases is a common concern among older adults.
Experts have established a clear link between alcohol and cancer, for example. According to the World Health Organization (WHO), alcohol consumption was responsible for almost 4% of cancers diagnosed worldwide in 2020. And, in the United States alone, alcohol is linked to an estimated 75,000 cancer cases and 19,000 cancer deaths each year.
The WHO adds that, in 2019, an estimated 474,000 deaths from cardiovascular diseases were caused by drinking alcohol. Alcohol is also associated with greater risk of liver diseases, heart diseases, and mental health conditions, including depression and anxiety.
According to a report by the NIA called Facts About Aging and Alcohol, older adults are at high risk for adverse reactions when mixing alcohol and medications. That’s because they’re more likely to have health issues that require medication. They may also be more forgetful about what they’ve taken or how much they’ve had to drink.
The NIA warns that all kinds of medicines (prescriptions, over-the-counter drugs, and even herbal ingredients) can lead to dangerous side effects when mixed with drinking.
For example, aspirin and alcohol combined increase the risk of internal bleeding. Taking cold and allergy medicines when drinking can cause excessive drowsiness. Acetominophen and alcohol can damage the liver. In some cases, mixing booze with sleeping pills, pain medication, or anxiety pills can lead to death. And consuming alcoholic drinks while taking antidepressant medications can increase suicide risk.
Keep in mind that some medicines themselves, including many over-the-counter cough syrups, contain high concentrations of alcohol. These can further increase the impact of other alcoholic drinks consumed.
Many people in the baby boomer generation grew up believing that drinking is a normal, acceptable, and even a healthy and necessary part of life. Today, thanks to further research on the myriad damaging effects of alcohol, we know these attitudes must change.
On top of all the potential dangers listed above, alcohol is metabolized differently among over-65 populations. They may find that the effects of drinking increase as they get older, or their tolerance lowers. This may be particularly dangerous for older women, since females—at any age—are biologically affected by alcohol differently than men.
The bottom line is that drinking alcohol negatively impacts both physical and mental health. Unfortunately, mental and physical health struggles (as well as facing the challenges that accompany aging) can lead to increased alcohol use.
These factors can create a dangerous, even deadly, combination for people over 65 who choose to drink—whether they imbibe in so-called moderation or excess. The best strategy for sticking to safe levels of drinking is to abstain altogether, at any age.
CDC. Data and Statistics on ADHD. (May 16, 2024). www.cdc.gov/adhd/data/index.html#:~:text=An%20estimated%207%20million%20(11.4,parents%20using%20data%20from%202022
Schiavone, N., Virta, M., Leppämäki, S. et al. Mortality in individuals with childhood ADHD or subthreshold symptoms – a prospective perinatal risk cohort study over 40 years.BMC Psychiatry 22, 325 (2022). https://doi.org/10.1186/s12888-022-03967-3
Schein J, Adler LA, Childress A, Gagnon-Sanschagrin P, Davidson M, Kinkead F, Cloutier M, Guérin A, Lefebvre P. Economic burden of attention-deficit/hyperactivity disorder among adults in the United States: a societal perspective. (November 22, 2021) Journal of Managed Care & Specialty Pharmacy. 2021;28(2). Available at: https://doi.org/10.18553/jmcp.2021.21290