
10 Unexpected Physical Symptoms of Anxiety
Anxiety isn’t just mental—it can trigger 10 surprising physical symptoms and weaken your immune system. Learn what to watch for.
Are you constantly waiting for something bad to happen? Do you routinely predict the worst? This pattern of thinking—known as catastrophic thinking or “worst-case scenario syndrome”—can hijack your peace of mind and wreak havoc on your mental well-being. It’s that spiral where a single setback snowballs into a full-blown disaster in your mind, even when there’s no real evidence to support it.
While it’s normal to worry occasionally, chronic catastrophizing is different. It trains your brain to expect the worst, amplifying fear, anxiety, and hopelessness. Over time, it can chip away at your confidence, relationships, and even your physical health.
The good news? You don’t have to stay stuck in this thought trap. Understanding why catastrophic thinking happens—and how to break free from it—can help you reclaim calm, clarity, and control in your life.
Chronic catastrophizing trains your brain to expect the worst, amplifying fear, anxiety, and hopelessness. Over time, it can chip away at your confidence, relationships, and even your physical health.
Catastrophizing is a term that was introduced in the 1960s and later popularized by psychiatrist Aaron Beck. This form of cognitive distortion that occurs when you anticipate something bad happening, and as a consequence, predict that something even worse will take place.
It is a type of automatic negative thought (ANT) that can ruin your day. Here are some examples of catastrophic thinking:
Do you see how one negative thought leads to another even bigger negative notion? These are “fortune-telling” ANTs that breed more ANTs. They multiply and eventually, the ANTs infest your mind.
Related: Do You Have an ANT Infestation in Your Head?
Most people who think this way don’t even realize they’re doing it. They take the littlest problems and turn them into major disasters waiting to happen. It can hold you back from trying new things or going for your goals.
When you’re constantly on edge expecting something awful to occur, it makes you feel stressed, depressed, and anxious.
Press Play to See How Catastrophic Thinking Haunted One Woman
In this video, Dr. Amen evaluates Miranda Pearman-Maday and her wife actress Raven-Symoné. Miranda opens up about having a catastrophic mentality and how it’s led to a life filled with fearful and anxious thoughts.
Click below to tune in:
Have you ever wondered why some people naturally think about the worst-case scenario, while others seem calm even during stressful times? At Amen Clinics, we’ve seen that certain psychological and environmental factors can make some individuals more likely to develop worst-case scenario syndrome.
Factors that increase catastrophic thinking include:
Related: The Long-Term Impacts of Adverse Childhood Experiences (ACEs)
Every time you have a thought, it causes the brain to release chemicals. Happy thoughts trigger the release of feel-good chemicals. Negative thoughts prompt the release of chemicals that make you feel bad. Catastrophizing triggers a cascade of feel-bad neurochemicals.
In addition, when catastrophic thinking occurs regularly, it strengthens neural pathways and causes it to become a habit. Each time you think something bad will happen then imagine an even more terrible consequence, you teach your brain to repeat the process.
Brain-imaging research shows that people who tend to predict the worst typically have abnormal activity in certain areas of the brain. One study on people with chronic pain who catastrophize revealed heightened activity in brain regions associated with emotions related to pain. This research also noted changes in the hypothalamus and pituitary responses.
At Amen Clinics, which has built the world’s largest database of brain scans related to behavior, SPECT scans show that people who catastrophize often have overactivity in the brain’s emotional and fear centers.
The brain activity abnormalities seen in Amen Clinics patients who engage in catastrophic thinking are also consistent with those who have anxiety disorders or major depressive disorder.
Scientific research supports these clinical findings and shows that having catastrophic thoughts rolling around in your head is associated with certain mental health disorders.
For example, findings in Child Psychiatry & Human Development analyzed thinking patterns in 2,802 teenagers and concluded that those who catastrophize are more likely to have anxiety problems.
Similarly, in a study on children, researchers noted a connection between catastrophic thinking and anxiety and depression. The association with depressive disorder was especially high in kids at 3rd grade level or younger.
Other scientific research has noted a link between catastrophizing and fatigue. For example, a systematic review in the Journal of Psychosomatic Research analyzed 14 previous studies and found a significant relationship between this unhealthy thinking pattern and exhaustion in 13 of them. This isn’t surprising as fatigue is one of the most common symptoms of depression.
This type of thinking can also develop after being exposed to some form of trauma. When a traumatic event occurs, it may make you believe that the worst can happen. To be prepared for the worst or to avoid it, you may begin actively playing out worst-case scenarios in your mind.
Catastrophic thinking can also increase the risk of developing other types of mental health problems. For example, a study involving nearly 80,000 active-duty soldiers found that those who had experienced a higher number of combat stressors combined with engaging in the most catastrophic thinking were 274% more likely to develop posttraumatic stress disorder (PTSD).
Understanding why you or someone else might be more prone to catastrophic thinking can:
With this insight, you’re better prepared to take meaningful steps to overcome catastrophic thinking. Next, let’s explore practical steps you can use to shift away from negative thinking patterns and regain control of your emotional well-being.
To end excessive worrying, you must first become aware that you’re doing it. If you find yourself ruminating on negative thoughts and predictions, make it a practice to write them down.
Take note of what may have preceded your downward spiral of thinking. Were you hungry or tired? Did you drink alcohol or have a fight with your significant other?
Avoiding triggers can help. Knowing that they may set you off can help you be ready to combat catastrophic thoughts can recognize them for what they are.
Ask yourself if the end-of-days thoughts you’re having are true. Make a list of any evidence that refutes them. Also make a list of any evidence that the opposite is true.
Catastrophic thinking doesn’t have to control your life. By becoming aware of these patterns, identifying your triggers, and actively challenging your negative thoughts, you can start rewiring your brain for greater calm, resilience, and hope. With practice and support, you can break free from the spiral of worst-case scenarios and move toward a more balanced, peaceful mindset.
Quartana, Phillip J et al. “Pain catastrophizing: a critical review.” Expert review of neurotherapeutics vol. 9,5 (2009): 745-58. doi:10.1586/ern.09.34
Chan, S.M., Chan, S.K. & Kwok, W.W. Ruminative and Catastrophizing Cognitive Styles Mediate the Association Between Daily Hassles and High Anxiety in Hong Kong Adolescents. Child Psychiatry Hum Dev 46, 57–66 (2015). https://doi.org/10.1007/s10578-014-0451-9
Noël, V.A., Francis, S.E., Williams-Outerbridge, K. et al. Catastrophizing As a Predictor of Depressive and Anxious Symptoms in Children. Cogn Ther Res 36, 311–320 (2012). https://doi.org/10.1007/s10608-011-9370-2
Lukkahatai, Nada, and Leorey N Saligan. “Association of catastrophizing and fatigue: a systematic review.” Journal of psychosomatic research vol. 74,2 (2013): 100-9. doi:10.1016/j.jpsychores.2012.11.006
Seligman, M. E. P., Allen, A. R., Vie, L. L., Ho, T. E., Scheier, L. M., Cornum, R., & Lester, P. B. (2019). PTSD: Catastrophizing in Combat as Risk and Protection. Clinical Psychological Science, 7(3), 516-529. https://doi.org/10.1177/2167702618813532
Anxiety isn’t just mental—it can trigger 10 surprising physical symptoms and weaken your immune system. Learn what to watch for.
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