
Superagers and Memory: The Surprising Key to a Younger Brain
Discover the surprising habit superagers—older people with rock solid memory function—all have in common.
Persistent, overwhelming fatigue, cloudy thinking, shortness of breath, body aches and pain—these troubling symptoms are the telltale signs of long COVID.
Yet, for an individual who has previously had a Lyme disease infection, the symptoms may be indicative of COVID-induced Lyme flare-ups—as long COVID symptoms and Lyme disease look alike. Or for someone who at some point in the past experienced an Epstein-Barr virus (EBV) infection or chronic fatigue syndrome (CFS), the symptoms may be a result of chronic illness triggers after COVID.
Indeed, nearly five years after the COVID-19 virus arrived in the U.S., scientists are still making discoveries about the long COVID immune response—and, specifically, COVID and immune system reactivation.
Here’s what you need to know how COVID impacts chronic illnesses and Lyme disease relapse after COVID.
A compromised long COVID immune response could leave an opportunity for previously dormant viral or bacterial infections to re-emerge.
Long COVID – also known as post-COVID condition – is a syndrome that occurs in individuals with a history of likely or confirmed SARS CoV-2 infection, usually about three months from the onset of COVID-19.
Long COVID comes with an array of symptoms that last for at least two months and cannot be explained by an alternative diagnosis to be considered long COVID. The most common symptoms may include any of the following:
These symptoms often have an impact on everyday functioning. Symptoms may appear for the first time following initial recovery from an acute COVID-19 episode, or they can persist from the time of the initial illness. Additionally, they may vary or relapse over time.
One of the most recent scientific surveys of nearly 30,000 participants revealed that about 8% of U.S. adults reported having ever had long COVID. Just under 4% of U.S. adults reported currently having the condition or currently having activity-limiting long COVID.
Of course, the SARS CoV-2 infection is the original initiator of long COVID, but more research is needed to fully understand what transpires at the cellular and molecular levels that brings about long COVID health complications and symptomology.
Scientists see long COVID more as an umbrella term because it appears there are likely multiple mechanisms that lead to its development and these conditions are not mutually exclusive—and may even coexist.
According to 2023 research, the leading theories about what drives long COVID include damage/alteration to the immune system, the persistence of residual COVID viral components that lead to chronic inflammation, endothelial (lining of blood vessels) dysfunction or activation, reactivation of pre-existing chronic infections, microflora imbalances in the gut, and unrepaired tissue damage.
Here’s a closer look at a few of them.
Viral persistence is characterized by ongoing shedding of SARS-CoV-2 after the acute infection has run its course. These persistent infections from long COVID shedding may fly under the radar, but their subclinical viral presence is thought to continuously aggravate the immune system – which, in turn, may trigger chronic inflammation.
Indeed, persistent COVID viral RNA was found in the feces of a group of individuals months after clearing the initial infection, according to one study reported by researchers at the Yale School of Medicine. These individuals also reported experiencing residual GI symptoms months after being diagnosed with COVID.
If long COVID develops due to subclinical levels of the virus persisting in the body, that would make the condition similar to other infection-associated chronic conditions (also called post-acute infection syndrome) such as CFS, Lyme disease, EBV, or herpes zoster (shingles) that develop after the acute infection has passed.
Because COVID can cause immune system dysfunction, scientists sought to explore an important question: Can COVID reactivate infections? After all, a compromised long COVID immune response could leave an opportunity for previously dormant viral or bacterial infections to re-emerge—especially the IACC’s just mentioned.
There’s a likely connection between COVID and immune system reactivation, evidence suggests. EBV, which causes mononucleosis and other illnesses, appears to be reactivated in some long COVID patients. Indeed, research shows that an increase of EBV antibody levels are present in some individuals with continuing long COVID symptoms.
Additionally, research has found many overlaps between long COVID symptomatology with clinical presentation of chronic fatigue syndrome. Twenty-five out of 29 known chronic fatigue symptoms were noted in one COVID study. However, it is still not exactly clear how COVID impacts chronic illnesses.
SARS-CoV-2 infection may trigger autoimmune disease. Some patients with long COVID have elevated levels of autoantibodies (malfunctioning immune cells), which are thought to play a role in autoimmune disorders such as rheumatoid arthritis, lupus, or Sjögren’s syndrome, Yale Medicine reports.
Antibodies help to protect against foreign invaders, such as bacteria and viruses. However, autoantibodies can attack the body’s own cells, leading to inflammation and tissue injury.
In some patients with long COVID, antinuclear autoantibodies have been observed up to one year after acute infection. They can target parts of cell nuclei, which may promote inflammation and damage organ systems.
For instance, in the inner lining of blood vessels (the endothelium), these antinuclear autoantibodies can create a hyper-inflammatory state or alterations to blood cells that can lead to inappropriate clotting.
Inflammation, or recruiting white blood cells and the release of cytokines that initiate tissue swelling and injury, may also underlie some types of long COVID. The acute phase of COVID infection alters tissue function and unleashes a chronic inflammatory state in cells, specifically cells in the brain that are longer-lived. Inflammation is one of the major chronic illness triggers after COVID.
All of the theories noted above may possibly contribute to the sustained inflammation seen in long COVID cases.
Lyme disease is a bacterial infection that develops after a person is bit by a tick carrying the infection-causing bacterium, Borrelia burgdorferi. In rare cases, Lyme can develop from another tick-carrying bacterium called Borrelia mayonii.
While cases of Lyme have been reported in all 50 sates in the U.S., the vast majority of Lyme disease is found in the Northeast, mid-Atlantic, and upper-Midwest.
When Lyme disease infection first occurs, the most common symptom is an erythema migrans rash. It appears like a red circle with a bullseye on the skin. Research has found about 70-80% of cases have this rash, which appears at the site of the tick bite.
Over time, other symptoms of Lyme disease may appear. However, some people may not notice any symptoms initially. The CDC notes that any of the following early symptoms of Lyme disease typically appear three to 30 days after the tick bite:
Days or even months after the tick bit, these later symptoms may appear:
Lyme disease may also trigger symptoms related to mental health conditions, such as:
And similar to long COVID, some Lyme patients continue to have ongoing symptoms, which can be severe and debilitating. The CDC calls this phenomenon post-treatment Lyme disease syndrome (PTLD), also known as chronic Lyme disease.
Many researchers and clinicians believe that the persistence of bacteria is the cause of these lingering symptoms. The antigen that triggers the inflammatory responses in chronic Lyme symptoms is found on the outer layer of the bacterial cell wall.
Pieces of these bacterial cell walls can linger in the body—undetected in the neurons or spinal cord, even post infection. This may contribute to the prolonged inflammation that leads to chronic illness.
According to a recent 2024 study in the Journal of Infectious Diseases, prevalence of PTLD varies from 0% to 48%, depending on how chronic Lyme disease is measured and defined. Some advocacy groups settle on a prevalence rate of 30%.
COVID symptoms and Lyme disease share similar symptoms, but that’s not all. In a 2022 study, researchers found that chronic Lyme and COVID-19 are linked as having a history of Lyme disease correlated to increased risk of severe COVID-19.
In fact, long COVID and Lyme disease have so many overlapping similar features, research has been conducted to find biomarkers that differentiate between the two conditions.
Unfortunately, without clear biomarkers, the lack of differences between them impedes scientific research, according to some experts. A potential participant in a trial might be sick from long COVID, Lyme, or another infection-associated chronic condition.
At Amen Clinics, brain SPECT imaging and lab work play important roles in helping determine the underlying root cause of symptoms.
At this point, there are currently no FDA-approved treatments for chronic Lyme, or full-scale clinical therapy trials, which is very common among chronic conditions. But there’s hope that with the prevalence of long COVID, new research will reveal therapies that may help treat all of these similar chronic conditions, such as COVID, Lyme, EBV, CFS, and the herpes zoster.
Until an effective treatment is found, post-COVID Lyme symptoms can be managed through lifestyle changes. (Of course, an acute Lyme infection requires antibiotics.) Here’s what you can do for chronic Lyme and long COVID symptoms:
Vhratian A, et al. Prevalence of Post–COVID-19 Condition and Activity-Limiting Post–COVID-19 Condition Among Adults. JAMA Netw Open. 2024;7(12):e2451151.
Liu Y, et al. Mechanisms of long COVID: An updated review. Chin Med J Pulm Crit Care Med. 2023 Dec 6;1(4):231-240.
Yale Medicine Website, https://www.yalemedicine.org/news/the-long-covid-puzzle-autoimmunity-inflammation-and-other-possible-causes. Accessed December 21, 2025
Snair M, Liao J, Ashby E, et al., editors. Toward a Common Research Agenda in Infection-Associated Chronic Illnesses: Proceedings of a Workshop. Washington (DC): National Academies Press (US); 2024 Apr 3. 2, Overview of Infection-Associated Chronic Illnesses.
Peluso, MJ, et al. Chronic viral coinfections differentially affect the likelihood of developing long COVID. J Clin Invest. 2023;133(3):e163669
Qanneta R. Long COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome: Similarities and differences of two peas in a pod. Reumatol Clin. 2022 Dec;18(10):626-628.
Yale Medicine Website, https://www.yalemedicine.org/news/the-long-covid-puzzle-autoimmunity-inflammation-and-other-possible-causes. Accessed December 20, 2025
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Discover the surprising habit superagers—older people with rock solid memory function—all have in common.

Discover the fibermaxxing trend and how fiber helps the gut microbiome, which benefits brain health, digestion, mood, and overall wellness.
No matter how fun or relaxing your Fridays and Saturdays feel, Sunday night is always just around the corner. And that can inspire dread for a lot of people who struggle with knowing how to prepare for the week ahead.
The so-called “Sunday Scaries” tend to creep up when you’re savoring the last hours of the weekend. One moment, you’re laughing with friends or watching your favorite show cozy on the couch—the next, your thoughts spiral into a flurry of anxiety: looming deadlines, tense meetings, or the grind of another workweek.
Sound familiar? It’s unfortunately all too familiar for mllions of people who experience this unease every Sunday. There is hope for overcoming Sunday night anxiety. There are simple, effective ways on how to beat the Sunday Scaries and set yourself up for a better week.
The term “Sunday Scaries” refers to the anticipatory anxiety that comes on Sunday evenings as people prepare for the workweek. While not a clinical diagnosis, the phenomenon is real and widespread. A LinkedIn study found that 80% of professionals experience Sunday night anxiety, with Millennials and Gen Z reporting the highest levels of stress. The symptoms to look out for can include:
This anxiety often stems from a combination of work pressure, unfinished weekend tasks, and negative associations with Mondays. In the United States, the problem is exacerbated by the hustle culture that keeps us “always on” and stressed. A study revealed that workers spend an average of eight hours per day outside of work reading, checking, and responding to emails and messages.
This blurring of boundaries makes it harder to truly relax over the weekend, leaving people scrambling on how to prepare for the week ahead.
A predictable, calming Sunday evening routine can help reduce anxiety and provide much-needed structure. Research shows that rituals and routines decrease stress by offering a sense of control. This could involve preparing meals for the week, organizing your schedule or room, or planning your clothes for the workweek.
A study published in the Journal of Occupational Health Psychology found that individuals who spent Sunday evenings engaging in productive but relaxing tasks felt less stressed on Monday mornings.
Incorporating calming activities like reading, journaling, or light yoga can also signal to your brain that it’s time to unwind.
According to a study by the American Psychological Association, mindfulness has been proven to significantly lower stress levels and improve emotional well-being. If you struggle to re-center yourself on Sunday nights, here are a few Sunday self-care strategies to consistently try for better weekly results:
There are even apps like Calm or Headspace offer guided meditations designed for Sunday anxiety relief. Even just 10 minutes of focused calm a few days a week can help shift your attention from future worries to the present moment.
Preparation is one of the most effective Sunday Scaries tips. Use part of your Sunday to organize your upcoming week. Write a to-do list for Monday or map out your key priorities.
Research has shown that having a clear plan for the week ahead can reduce anxiety and instill more positie habits that foster a sense of readiness. Plus, resetting your mind for Monday doesn’t have to feel overwhelming.
Keep your planning session short and focused—maybe 10 to 20 minutes—by writing down your goals alongside your calendar to block off time you may need to complete or rest in-between each task. The goal is to alleviate uncertainty, not create more stress.
Scrolling through work emails or social media late on a Sunday can fuel end-of-weekend anxiety. A 2022 study revealed that excessive screen time before bed disrupts sleep, exacerbates stress levels, and increases the likelihood of depression.
The goal should be to establish a digital detox period on Sunday evenings—perhaps an hour or two before bedtime—so it becomes a net positive habit in your lifestyle.
Replace screen time with simple and relaxing Sunday habits for a better week like reading, taking a bath, or listening to calming music while you do your self-care nighttime routine.
This not only helps with overcoming Sunday night anxiety but also can improve REM sleep quality to set you up for a more productive Monday.
Much of Sunday anxiety stems from negative perceptions (and experiences) of Mondays. However, a Harvard University study found that starting the week with good intentions can shift your mindset to better follow-through with tasks for the week. Instead of dreading Mondays, view it as an opportunity for a fresh start to creating a calendar you can build with things you also enjoy.
Focusing on gratitude is a key factor in how you shape and set the tone of your week. Sunday Scaries Tip: Write down three things you’re looking forward to or thankful for in the upcoming week. This simple exercise can transform your outlook and make Mondays feel less daunting.
Self-care isn’t just about face masks and bubble baths—though they can do wonders for the physical tension you may feel—it’s about nurturing your mental health. Engage in activities that rejuvenate and calm you, whether that’s taking a walk in nature, practicing a creative hobby, or spending quality time with loved ones.
Research shows that spending time outdoors significantly reduces cortisol levels, the stress hormone linked to Sunday Scaries. So, a Sunday afternoon hike or picnic could be just what you need to feel refreshed before planning out your week.
Physical activity is one of the best ways to combat stress and improve mood. According to the Mayo Clinic, exercise releases endorphins, which act as natural mood elevators. A Sunday workout—even a light one like yoga or a brisk walk—can help alleviate anxiety and improve your mindset for the week ahead.
To make this habit sustainable, choose an activity you enjoy that can also improve your physical health. Whether it’s a dance class, strength training, cycling, or stretching, the key is to move your body in a way that feels good to you. It can become one of the most productive ways to end your weekend by completing a goal to start your week.
Rather than viewing Sunday as the end of the weekend, treat it as an opportunity to create meaningful moments at the start. Spend time with friends, family, or even yourself doing something enjoyable. A study published in The American Journal of Lifetyle Medicine found that social connections are a key predictor of happiness and siginfiicant stress reduction.
Plan a low-pressure activity, like a casual dinner with loved ones or a relaxing movie night. These moments of joy can help counterbalance the Sunday Scaries and remind you that the weekend isn’t over yet.
One of the most common symptoms of Sunday anxiety is trouble sleeping. Poor sleep, in turn, exacerbates anxiety, creating a vicious cycle. The National Sleep Foundation recommends establishing a consistent sleep schedule and practicing good sleep hygiene. For example:
On Sunday nights, avoid caffeine and alcohol, both of which can disrupt sleep. Create a calming bedtime routine—dim the lights, sip on herbal tea or magnesium cocktail, and read a book. Quality sleep is essential for managing mental health and Sunday Scaries. Stress management for Sunday nights is possible, so don’t underestimate its power in resetting your mind for Monday.
The Sunday Scaries may feel inevitable, but the right strategies can transform your usual coping with end-of-weekend anxiety into a time of peace and preparation. From establishing relaxing Sunday habits to practicing mindfulness and self-care, these tips can help you approach the workweek with confidence and calm.
Remember, overcoming Sunday night anxiety is a journey, not a race. Start small—implement one or two of these Sunday self-care strategies at a time—and build from there. Make your Sundays a time for reflection, relaxation, and readiness to beat the Sunday Scaries and create happier, healthier weeks from now on.
Heitmann, B. (2018, September 28). Your guide to winning at work: Decoding the Sunday Scaries. LinkedIn. Retrieved from https://www.linkedin.com/blog/member/career/your-guide-to-winning-work-decoding-the-sunday-scaries
Sanfilippo, M. (2024, January 26). What after-hours emails really do to your employees. Business News Daily. Retrieved from https://www.businessnewsdaily.com/9241-check-email-after-work.html
Bhandari, S., MD, & WebMD Editorial Contributors. (2024, September 19). Psychological benefits of routines. WebMD. Retrieved from https://www.webmd.com/mental-health/psychological-benefits-of-routine
American Psychological Association. (2019, October 30). Mindfulness meditation: A research-proven way to reduce stress. https://www.apa.org/topics/mindfulness/meditation
Cole, S. A., Sannidhi, D., Jadotte, Y. T., & Rozanski, A. (2023, May 26). Using motivational interviewing and brief action planning for adopting and maintaining positive health behaviors. ScienceDirect. https://www.sciencedirect.com/science/article/pii/S0033062023000099#ab0005
Nakshine VS, Thute P, Khatib MN, Sarkar B. Increased Screen Time as a Cause of Declining Physical, Psychological Health, and Sleep Patterns: A Literary Review. Cureus. 2022 Oct 8;14(10):e30051. doi: 10.7759/cureus.30051. PMID: 36381869; PMCID: PMC9638701.
Rogers, T., Milkman, K. L., John, L. K., & Norton, M. I. (2015). Beyond good intentions: Prompting people to make plans improves follow-through on important tasks. Behavioral Science & Policy, 1(2). https://scholar.harvard.edu/files/todd_rogers/files/beyond_good_intentions_-_prompting_people.pdf
Jones R, Tarter R, Ross AM. Greenspace Interventions, Stress and Cortisol: A Scoping Review. Int J Environ Res Public Health. 2021 Mar 10;18(6):2802. doi: 10.3390/ijerph18062802. PMID: 33801917; PMCID: PMC8001092.
Mayo Clinic Staff. (2022, August 3). Exercise and stress: Get moving to manage stress. Mayo Clinic. www.mayoclinic.org/healthy-lifestyle/stress-management/in-depth/exercise-and-stress/art-20044469
Martino J, Pegg J, Frates EP. The Connection Prescription: Using the Power of Social Interactions and the Deep Desire for Connectedness to Empower Health and Wellness. Am J Lifestyle Med. 2015 Oct 7;11(6):466-475. doi: 10.1177/1559827615608788. PMID: 30202372; PMCID: PMC6125010.
Suni, E., and Rosen, D., MD. (2024, March 4). Mastering sleep hygiene: Your path to quality sleep. Sleep Foundation. www.sleepfoundation.org/sleep-hygiene

Discover the surprising habit superagers—older people with rock solid memory function—all have in common.

Discover the fibermaxxing trend and how fiber helps the gut microbiome, which benefits brain health, digestion, mood, and overall wellness.
Rejection hurts. Whether it’s getting turned down by a potential love interest, being criticized by your boss, or getting picked last for your company softball team, getting rejected sucks. Most of us are able to shake it off and move on with our lives. For some people, however, being rebuffed—or simply perceiving rejection—can trigger severe emotional reactions. This is called rejection sensitive dysphoria (RSD).
For some people, however, being rebuffed—or simply perceiving rejection—can trigger severe emotional reactions. This is called rejection sensitive dysphoria (RSD).
Rejection sensitive dysphoria is a form of emotional dysregulation. Although it is not classified as a mental disorder, it can be highly disruptive in daily life.
People with rejection sensitive dysphoria experience an overwhelming emotional response to real or perceived rejection, criticism, judgment, or being left out. They may lash out in anger, dwell on negative thoughts, feel hopeless, think they’re a failure, or feel their self-esteem plummet.
Their moods may drop so rapidly and dramatically, it can feel like major depression and can lead to suicidal thoughts and behavior.
As a result of these intensely distressing feelings, people with RSD tend to avoid social situations, become perfectionists, develop an extreme fear of failure, and adopt people-pleasing attitudes.
Because the symptoms and consequences associated with rejection sensitivity are similar to those seen in many other mental health conditions, it is often overlooked or misdiagnosed.
RSD is real, and it can affect anyone, but it is more commonly seen in people who have one or more of the following three mental health conditions:
According to the American Psychiatric Association’s 2024 mental health poll, 43% of Americans reported feeling more anxious than the year before. Some of the top anxiety-inducing issues reported in 2024 were the economy, the presidential elections, and gun violence.
ADHD is a brain-based disorder that is associated with an array of behavioral and emotional symptoms, including short attention span, distractibility, poor impulse control, irritability, being easily stressed, and a sense of insecurity. Having ADD tends to amplify emotions, including those related to rejection.
Combined with heightened sensory reactions, this adds up to extreme hypersensitivity to criticism. Emerging research suggests that people with autism may experience greater rejection-induced social pain, which can then lead to psychological distress.
Other research has found that people who are highly sensitive to rejection are at increased risk of depression, borderline personality disorder, and body dysmorphic disorder.
According to brain-imaging research in Social Neuroscience, people with higher levels of rejection sensitivity experience activation in specific regions of the brain when looking at faces displaying disapproval.
At Amen Clinics, which has built the world’s largest database of functional brain scans related to behavior, people who are hypersensitive to rejection tend to have overactivity in certain regions of the brain. Single photon emission computed tomography (SPECT) scans performed at Amen Clinics show that these areas include:
Too much activity in the basal ganglia is associated with heightened anxiety. When there is hyperactivity in the ACG, it is linked to getting stuck on negative thoughts and worries, like “I’m going to say the wrong thing, and everybody will laugh at me.”
How can you tell if you have RSD? Only a professional who performs a comprehensive examination including functional brain imaging and lab tests to help identify possible root causes for your symptoms can give an accurate diagnosis.
However, if you recognize yourself in the following traits, it’s worth investigating RSD further with an integrative neuropsychiatrist.
If you’re struggling with rejection sensitivity, here are 5 strategies that can help.
Learn to kill the ANTs (automatic negative thoughts) that make you feel rejected. Ask yourself if your thoughts are really true and talk back to them. This is especially true if you have suicidal thoughts. Many people have thoughts of taking their own life, but they don’t act on them.
One study found that over half of all college students had suicidal thoughts during their lifetime. Suicide is a permanent solution to a temporary feeling. And if you hurt yourself, you’re teaching your kids that this is how grown-ups solve problems.
American Psychiatric Association. American Adults Express Increasing Anxiousness in Annual Poll; Stress and Sleep are Key Factors Impacting Mental Health. May 1, 2024. https://www.psychiatry.org/news-room/news-releases/annual-poll-adults-express-increasing-anxiousness
Ginapp, Callie M et al. “”Dysregulated not deficit”: A qualitative study on symptomatology of ADHD in young adults.” PloS one vol. 18,10 e0292721. 12 Oct. 2023, doi:10.1371/journal.pone.0292721
Lin, Xinxin et al. “Autistic traits heighten sensitivity to rejection-induced social pain.” Annals of the New York Academy of Sciences vol. 1517,1 (2022): 286-299. doi:10.1111/nyas.14880
Gao S et al. Associations between rejection sensitivity and mental health outcomes: A meta-analytic review. Clinical Psychology Review, Volume 57, November 2017, Pages 59-74. https://doi.org/10.1016/j.cpr.2017.08.007
Burklund, L. J., Eisenberger, N. I., & Lieberman, M. D. (2007). The face of rejection: Rejection sensitivity moderates dorsal anterior cingulate activity to disapproving facial expressions. Social Neuroscience, 2(3–4), 238–253. https://doi.org/10.1080/17470910701391711
ABC News. More Than 50% of College Students Felt Suicidal. November 5, 2008. https://abcnews.go.com/Health/DepressionNews/50-college-students-felt-suicidal/story?id=5603837

Discover the surprising habit superagers—older people with rock solid memory function—all have in common.

Discover the fibermaxxing trend and how fiber helps the gut microbiome, which benefits brain health, digestion, mood, and overall wellness.
If your child catches the flu or sprains an ankle on the soccer field, you can see visible signs of the problem and you know what to do to treat it. But when it comes to your child’s mental health, it’s not so cut and dried.
Too many children and adolescents with mental health conditions go untreated. Research has found that approximately 70-80% of children with mental health disorders go without care.
A child’s poor behavior or a depressed mood might be attributed to temperament or a developmental phase. Add to that the stigma surrounding mental health disorders and the challenge and expense of addressing them, it’s easy to see how parents may not readily see a problem, as research has found.
Yet, a child’s mental health is paramount to their well-being and success in life. It’s especially important to identify and treat mental health issues early when they start. The National Alliance on Mental Health reports that 50% of lifetime mental disorders start by about age 14, and 75% by age 24.
Allowing a child’s symptoms to go unchecked can increase the chances of failing in school, limit their opportunities to go to college, lessen their ability to get the job they want, and set them up for a lifetime of difficulty in relationships with others. A parent’s worst nightmare, it can lead to suicidal thoughts and behavior.
But it is not all gloom and doom. Mental health conditions are highly treatable. As a parent, you can educate yourself about mental health challenges that children and teens commonly face, as well as the warning signs of a mental health problem.
Here’s your guide to children’s mental health, including tips for parenting to support your child’s mental well-being now and into adulthood.
Mental health conditions among children and adolescents are surprisingly common. According to the latest available data (collected in 2018-2019) from the U.S. Centers for Disease Control and Prevention (CDC), 1 in 7 children ages 3 to 17 (13%) had a current, diagnosed mental or behavioral health condition. As several years have passed since the data collection, that figure is estimated to be higher today.
The most common childhood mental health conditions are attention deficit (ADD), also known as attention-deficit/hyperactivity disorder (ADHD); anxiety disorders; behavioral problems (including oppositional defiant disorder and anger issues); and depression (or mood disorders).
Here are the latest available statistics for each condition:
CDC data collected from 2021–2022 reports the following:
Of course, there are other mental health disorders in children too. Children and teens can suffer from obsessive-compulsive disorder (OCD), bipolar disorder, autism spectrum disorder (ASD), eating disorders, PTSD, PANDAS, tourette syndrome, schizophrenia, aggression, learning disabilities, substance abuse problems, and traumatic brain injury (TBI), to name several.
It’s not uncommon for a child or teen to have more than one mental health disorder. For example, the CDC reports a 2022 survey showed more than 75% of children with ADD/ADHD had at least one other co-occurring condition. If you recognize multiple signs and symptoms in your child, it could mean that co-occurring conditions are at play.
A parent’s greatest concern, suicidality, is a high risk among teens. An estimated 2 million adolescents attempt suicide each year. It is the second leading cause of death for children and young adults ages 10 to 24 after unintentional injuries.
Unfortunately, too many children and adolescents with mental health conditions go untreated. Research has found that approximately 70-80% of children with mental health disorders go without care.
While these statistics are sobering, the good news is that research shows early diagnosis and treatment of mental health conditions show better outcomes for children and adolescents as adults. Parents play a crucial role in helping to spot the signs of a mental health problem when it starts.
Indeed, one of the best things you can do as a parent for your child’s mental health is know the signs. The difficulty is in discerning a period of troublesome behavior and emotional problems from a true mental health condition.
Keep these questions in mind to help you figure out if your child may need to see someone:
If the answer is yes, that’s a clear indication it is time to seek help. Remember, failing to address these types of signals can increase the chances of your child having a lifetime of mental health struggles.
Signs of a Mental Health Problem in Younger Children
At Amen Clinics, our mental health experts have additionally noted the following less noticeable signs of mental health problems in children and teens:
Here are some indicators that your child may have one or more of the four most common mental health conditions among kids and teens: ADD/ADHD, anxiety, behavioral problems, or depression:
ADD/ADHD in children symptoms include inattention, trouble focusing, being easily distracted, frequent daydreams, overfocused attention, hyperactivity, an inability to sit still, and disorganization.
If you are wondering how to help a child with anxiety, you can start by identifying if they have any of the following signs:
Child behavior problems might include impulsivity, compulsive behaviors, anger or aggression issues, negativity, nervousness, disruptive talking, inappropriate actions, manipulation, defiance, inattention, or antisocial behavior.
There are five common signs of depression in kids:
Researchers analyzed epidemiological data from more than 6,000 children and parents to determine signs of more serious psychiatric issues. They came up with the following 11 warning signs that were published in the medical journal Pediatrics. If you recognize your child as exhibiting even one of these signs, it is cause to seek out help from a pediatrician or qualified mental health professional as soon as possible.
If you observe just one of these behaviors in your child or teen, it is recommended that you take them to see a qualified mental health professional for an evaluation.
It’s important for parents to address any stigma they may carry about mental health disorders. The truth is mental health disorders are brain health disorders and multiple factors play into their development. Rather than being character flaws or personal weakness, mental conditions have a neurological and biological basis. Compromised brain function or damaged brain structure oftentimes contribute to their development. Genetic, lifestyle, temperament, and life experiences can all influence mental health too.
In order to properly diagnose and treat mental health conditions, Amen Clinics uses brain SPECT imaging, which measures brain blood flow patterns. By examining cerebral blood flow, areas of the brain that are overworking, underworking, or functioning normally can be identified. Looking at what is happening in the brain allows for a more accurate diagnosis and a tailored treatment plan.
While talk therapy and medication may be necessary in treating some pediatric mental health issues, oftentimes adjusting lifestyle factors to support brain health can improve a child’s condition dramatically. That might mean making dietary changes, starting nutritional supplementation, implementing physical activity, ensuring restful sleep, and more.
If you believe your child is suffering from a mental health condition, in addition to seeing your child’s pediatrician or a qualified mental health professional, there are things you can do. Take measures in your parenting style and at home to ensure you are prioritizing brain healthy habits as well as good mental health practices. As most adults don’t even know how to talk to kids about mental health, there may be a learning curb! Be patient.
Below are suggestions gleaned from Raising Mentally Strong Kids a book by Amen Clinics’ founder, Daniel Amen, MD, and Charles Fay, PhD.
Teach your child the importance of prioritizing mental health. Be proactive in addressing any mental health concerns your child may have. Readily seek professional support when needed. Make a safe space or time for your child to share openly with you. (This might be at bedtime for younger children or during a car ride for teens.) Listen and validate your child’s experiences without being reactive or “fixing.” It’s important for them to feel you genuinely want to hear about their life in a supportive, non-judgmental way.
Automatic negative thoughts can fan the flames of depression, anxiety, and other mental health issues. You can teach your child how to challenge negative thoughts (such as black-and-white “all or nothing,” always/never thoughts) and replace them with constructive, optimistic perspectives. This practice boosts self-esteem and helps your child develop resilience.
What your child eats plays a huge role in how they feel mentally. A diet rich in omega-3 fatty acids and other healthy fats, lean proteins, antioxidant and nutrient-rich fruits, vegetables, legumes, and complex carbohydrates – are all excellent for brain health. Limit consumption of foods that may compromise brain or digestive health such as sugar, artificial sweeteners, food additives, processed foods, and gluten.
Kids need to move their bodies! Exercise enhances brain function, improves mood, and reduces stress.
Setting healthy boundaries around the use of technology is essential for your child’s mental health. A number of mental health conditions are exacerbated by overuse of social media. Encouraging face-to-face interactions, creative play, and outdoor activities are much better alternatives to screen time.
Model and teach your child to recognize, understand, and manage their emotions. If appropriate, introduce your child or teen to deep breathing and meditation – great tools for emotional self-regulation.
Maintaining open communication, setting clear expectations, and providing consistent encouragement and praise are all part of creating a healthy environment for your child.
Involving your child in some decision-making processes and encouraging them to think critically about the consequences of their actions fosters independence and confidence in their ability to handle challenges.
Teach your child that they can grow with effort and perseverance. This mindset will help them view challenges as opportunities for growth rather than obstacles.
Villatro AP, et al. Parental Recognition of Preadolescent Mental Health Problems: Does Stigma Matter? Soc Sci Med. 2018 Sep 22;216:88–96.
National Alliance of Mental Illness website
Accessed January 24, 2025
U.S. Centers for Disease Control and Prevention website
Accessed January 24, 2025
U.S. Centers for Disease Control and Prevention website
NCHS Data Brief, No. 499, March 2024
https://www.cdc.gov/nchs/data/databriefs/db499.pdf
Accessed January 24, 2025
U.S. Centers for Disease Control and Prevention website
Accessed January 24, 2025
Koppelman J. Children with Mental Disorders: Making Sense of Their Needs and the Systems That Help Them [Internet]. Washington (DC): National Health Policy Forum; 2004 Jun 4. (Issue Brief, No. 799.)
2022 National Healthcare Quality and Disparities Report [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2022 Oct. CHILD AND ADOLESCENT MENTAL HEALTH.
Jensen P, et al. Overlooked and Underserved: “Action Signs” for Identifying Children With Unmet Mental Health Needs. Pediatrics. 2011 Nov;128(5):970–979.

Discover the surprising habit superagers—older people with rock solid memory function—all have in common.

Discover the fibermaxxing trend and how fiber helps the gut microbiome, which benefits brain health, digestion, mood, and overall wellness.
Did you know that there is more than one type of attention-deficit/hyperactivity disorder (ADHD), also known as attention-deficit disorder (ADD)? In fact, over 30 years of brain-imaging work at Amen Clinics—over 250,000 SPECT scans—show that there are 7 types of ADD/ADHD.
One of the most recently identified types is called anxious ADD/ADHD. Think of it as anxiety and inattention combined. Why is it so important to know if you have this type? One of the reasons is because standard treatments, such as taking stimulant medications alone, may make anxiety worse in these individuals.
The brain-imaging work using SPECT scans at Amen Clinics shows that there are 7 types of ADD/ADHD and each has a unique set of symptoms that requires a customized treatment plan.
In part 7 of this 7-part blog series, you’ll learn more about anxious ADD, its signs and symptoms, what SPECT scans show about this type, and science-backed strategies to reduce symptoms.
ADHD, or ADD, is a neuropsychiatric disorder that is characterized by problems with focus, impulse control, and hyperactivity (in some cases). Commonly diagnosed in childhood, ADD/ADHD may persist throughout adulthood.
Some people may have signs and symptoms of ADHD but go undiagnosed as children. These individuals may struggle with symptoms for years or even decades before finally getting diagnosed with adult ADHD.
Among patients at Amen Clinics, anxious ADD/ADHD is becoming more prevalent. Unlike the other types of the condition, people with this type typically don’t seek excitement and conflict.
In fact, it’s more common for these individuals to avoid situations that cause stress or conflict.
People who have anxious ADD/ADHD often latch onto the worst possible outcome and fixate on it. Those with this ADD/ADHD type frequently freeze in situations that trigger anxiety, such as taking a test or giving a big presentation.
How does anxious ADD/ADHD differ from anxiety disorders? In general, anxiety disorders tend to fluctuate over time, while anxious ADHD symptoms typically remain constant.
Core symptoms of ADHD that are seen in all 7 types of the condition include:
People may have some or all of these symptoms, which can range from mild to severe.
In addition to the common symptoms listed above, the signs and symptoms of anxious ADHD include:
As with the core symptoms, these can vary in terms of severity.
At rest and concentration there’s increased activity in the basal ganglia. With concentration, there is decreased activity in the prefrontal cortex and cerebellum.
As with most of the 7 ADD/ADHD types, this type is associated with abnormal brain function. During concentration, blood flow to the brain decreases, which lowers the ability to focus or pay attention.
On SPECT scans of people with anxious ADD/ADHD, blood flow decreases are seen in the prefrontal cortex and the cerebellum. Reduced blood flow in these areas is associated with difficulties with planning, focus, organization, impulse control, empathy, and judgment.
What’s unique about brain activity in these individuals is that there is also increased activity in an area called the basal ganglia. This uptick in brain activity is seen at rest and during concentration.
In the images below, red and white represent the highest levels of activity, while blue indicates average activity. In the anxious ADD/ADHD SPECT scan, there is overactivity in the basal ganglia.
Stimulant medications aren’t the only way to treat ADD/ADHD. There are also many natural ways to help ADD/ADHD. Science-backed strategies include:
The main treatment goal for this type is to promote relaxation. There are a variety of relaxation methods, including: meditating, diaphragmatic breathing and listening to calming music. Find relaxation techniques that work for you and use it whenever you feel stressed.
Nutritional supplements such as GABA, L-theanine, and magnesium can produce a sense of calm and relaxation. Multivitamin/mineral supplements and omega-3 fatty acids can improve focus and mental energy.
Your diet is another aspect that can help you control the anxious symptoms associated with this ADD type. Individuals with anxious ADD/ADHD should eat a lower-carbohydrate, higher-protein diet. Cutting out artificial sweeteners and MSG can also support healthy dopamine and GABA levels.
Laughing reduces stress and increases the release of endorphins in the brain. Laughter truly is the best medicine and can work wonders in relieving anxiety.
People with this type tend to avoid conflict, but it’s an absolute must to let friends and family know when you’re emotionally overwhelmed. If necessary, seek help from a mental health professional.
Having this type may increase the likelihood of saying yes to every request you get without thinking about the ramifications. You may agree to participate in projects to avoid seeming disagreeable, but it can end up making you feel overloaded. Learning how to say no is a skill you need to develop. Whenever someone asks you to do something, make it a habit to say, “Let me think about it.” This will give you time to decide if it’s something that is worth your time and effort.
Having anxious ADD/ADHD requires personalized solutions. For example, taking stimulant medications alone may improve focus and attention, but it can also exacerbate symptoms of anxiousness. To find the most effective treatment plan for your needs, it’s important to know two things:
To identify your type of ADHD, consider getting a brain SPECT scan. The blood flow and activity patterns in the brain can be very helpful in determining your type. Without looking at the brain, psychiatrists and other physicians can only guess if you have ADD/ADHD and which type you might have.
Want more information? Download Amen Clinics’ free Getting to Know the 7 ADD Types eBook.
Villatro AP, et al. Parental Recognition of Preadolescent Mental Health Problems: Does Stigma Matter? Soc Sci Med. 2018 Sep 22;216:88–96.
National Alliance of Mental Illness website
Accessed January 24, 2025
U.S. Centers for Disease Control and Prevention website
Accessed January 24, 2025
U.S. Centers for Disease Control and Prevention website
NCHS Data Brief, No. 499, March 2024
https://www.cdc.gov/nchs/data/databriefs/db499.pdf
Accessed January 24, 2025
U.S. Centers for Disease Control and Prevention website
Accessed January 24, 2025
Koppelman J. Children with Mental Disorders: Making Sense of Their Needs and the Systems That Help Them [Internet]. Washington (DC): National Health Policy Forum; 2004 Jun 4. (Issue Brief, No. 799.)
2022 National Healthcare Quality and Disparities Report [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2022 Oct. CHILD AND ADOLESCENT MENTAL HEALTH.
Jensen P, et al. Overlooked and Underserved: “Action Signs” for Identifying Children With Unmet Mental Health Needs. Pediatrics. 2011 Nov;128(5):970–979.

Discover the surprising habit superagers—older people with rock solid memory function—all have in common.

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It’s not all sunshine when it comes to the food color additive Yellow Dye 5 and your brain function, mental well-being, and overall health.
Synthetic food dyes are in everything from candy to baked goods, and from juices to toothpaste, mouthwash, and over the counter medicines. If you want to be a fierce protector of brain health for yourself or your loved ones, it’s important to pay attention to the most ubiquitous and potentially harmful synthetic dyes.
The biggest culprits? Yellow Dye 5, Red Dye 40, and Yellow Dye 6 account for 90% of all dyes used in foods, drugs, and cosmetics. These dyes can impact your brain function and mental health, trigger allergic reactions, and may potentially cause harm to your overall health when consumed above the recommended daily intake (RDI) over time.
Other countries have placed warning labels on products containing Yellow Dye 5 or have banned this synthetic dye in food products altogether because of the potential health risks it poses.
Unfortunately, the U.S. Food and Drug Administration (FDA) does not require warnings on products that contain these dyes, so concerned consumers must do their due diligence to minimize or eliminate consumption of them.
Here’s what you need to know about Yellow 5 and brain health and what you can do to protect yourself and your children from potential harm.
Yellow Dye 5, also commonly known as Yellow 5 or tartrazine, is an artificial yellow food colorant added to food, personal care products, and medications. It’s one of seven synthetic food colorants derived from petroleum and approved by the FDA. After Red 40, it is the most widely used dye.
It’s most often found in processed pastries and cereals; brightly colored soda; colored candy; personal care products such as mouthwash, cosmetics, toothpaste, and liquid soaps; and in prescription drugs and over-the-counter medications like cough syrup. However, you can also find it in unsuspecting foods such as pickles or butter!
A bright yellow dye, tartrazine is a more stable and cheaper alternative to natural food dyes. Food manufacturers use it to help make their products more enticing to consumers. Adding this synthetic color serves a number of important functions including the following:
Manufacturers are required to list dyes like Yellow 5 on the ingredient label. However, sometimes it can be hard to spot because tartrazine goes by many different names. Here are some of the most common:
A number of human and animal studies indicate a link between consumption of Yellow 5 and consequential health risks, even though the dye is FDA approved. Other countries have placed warning labels on products containing Yellow 5 or have banned this synthetic dye in food products altogether because of the potential health risks it poses.
Let’s start by looking at artificial dyes and brain health and, specifically, tartrazine and brain function. A 2024 review study of human and animal research on the effects of synthetic dye consumption on brain health came to a significant conclusion stating, “… evidence suggests that these dyes can significantly impact brain function and overall neurological health.”
That conclusion was about artificial dyes as a group. But is Yellow Dye bad for your brain? Animal research suggests it might be. In a study on tartrazine consumption in rats, researchers found that memory, learning, and behavior was impacted.
Indeed, a smaller volume size of the medial prefrontal cortex was observed in the rats given a daily dose of tartrazine greater than the acceptable daily intake (ADI). Subjects taking the ADI daily dose of tartrazine showed lower numbers of neurons and shorter dendrites.
The medial prefrontal cortex is an area of the brain involved with attention, cognition, action, and emotion. These impacts could affect spatial memory, decision-making, attention, and mood. Researchers in another 2022 study review stated that the animal research findings may predict similar effects in children.
It’s important to note that some experts believe it is possible for children to exceed the ADI of 7.5mg/kg of body weight (one kg is about 2.2 pounds), considering one serving of some cereals, beverages, and snack foods combined can exceed ADI limits.
That brings us to how Yellow Dye 5 affects children’s behavior. Research indicates that there’s a tartrazine hyperactivity link.
A significant 2007 study examined hyperactivity in 267 children (a combination of 3-year-olds and 8/9-year-olds) who were given a mix of artificial food color and additives. This randomized, double-blinded, placebo-controlled trial found that artificial colors in the diet resulted in increased hyperactivity in 3-year-old and 8/9-year-old children in the general population.
Considerable research has been conducted since that time on hyperactivity and artificial food dye consumption. A 2021 report based on human and animal research titled “Health Effects Assessment: Potential Neurobehavioral Effects of Synthetic Food Dyes in Children” revealed that synthetic food dyes might lead to neurobehavioral effects manifesting not just during a child’s developmental stages but later in life.
Additionally, a section of the report noted animal models exploring ADHD symptoms and dyes suggests involvement of dopaminergic, noradrenergic, and serotonergic systems, as well as more basic problems in neurotransmission. Importantly, the reports stated that current ADIs may not provide adequate protection from neurobehavioral impacts in children.
A review from 2022 found that current evidence from human studies suggests a relationship between food dye exposure and adverse behavioral outcomes in children—with or without behavioral disorders.
This touches on the correlation between artificial food dyes and attention deficit hyperactivity disorder (ADHD). Most experts agree that there’s a negative impact of artificial dyes on ADHD symptoms, but not necessarily a causative effect.
One review found that restricting consumption of artificial food colorants would benefit some children with ADHD. When you consider that more than 7 million U.S. children have ADHD, also known as attention deficit disorder (ADD), a restrictive diet could be beneficial to probably hundreds of thousands of them.
Some research has singled out Yellow 5 as particularly troublesome for suspected hyperactive children. One study on children showing hyperactive behavior examined their behavior both after consuming tartrazine and after abstaining from tartrazine. An increase in Yellow Dye 5 ADHD-related symptoms was observed.
The study found behavioral changes in irritability, restlessness, and sleep disturbance were associated with the ingestion of tartrazine in some children.
In vitro studies have shown that tartrazine is toxic to DNA. The dye was shown to have significant genotoxic effects at all concentration levels tested in one in vitro study. The researchers of this study warned that tartrazine could be harmful to health and prolonged use could potentially trigger carcinogenesis.
In a recent 2023 animal study, a synthetic dye caused DNA damage, colonic inflammation, and impacted the microbiome in mice. Some researchers are concerned that synthetic dye consumption may be linked, in part, to the increased rates of colon cancer among younger people, according to a recent report.
A small number of individuals have an allergy or sensitivity to Yellow Dye 5 and other artificial food colorings. People with food additive sensitivities in general, individuals with ADHD symptoms, and people who are sensitive to aspirin and NSAIDs are the most vulnerable to negative tartrazine effects and might benefit from being extra cautious about eating any foods that might contain this dye.
The most common tartrazine sensitivity side effects are skin rashes (hives), asthma, itching, coughing, and vomiting, research has found. Other less common reactions include inflammation of the blood vessels (vasculitis), small flat blood spots on the skin (purpura), and contact dermatitis (contact skin rash). Some research indicates that there may be a genetic component to food dye sensitivity.
You can protect yourself and your loved ones from potential negative health effects from Yellow Dye by eliminating or limiting foods that contain artificial food coloring from your diet. Since foods that contain Yellow Dye are usually heavily processed, it’s probably a good thing to do!
Here are foods that typically contain Yellow Dye 5:
Some brand name items with Yellow Dye include Doritos, Froot Loops, Lemon-flavored Jello, Knorr chicken bouillon, M&Ms, and Starburst.
More research on and information about artificial dyes and health will continue to be conducted and released.
Stay informed about Yellow 5 and other synthetic dyes in your food, cosmetics, medicines, and personal care products by visiting the Environmental Working Group and the Center for Science in the Public Interest websites and discussing your concerns with your medical doctor.
Damothoran K, et al. Biochemical processes mediating neurotoxicity induced by synthetic food dyes: A review of current evidence. Chemosphere. 2024 Sep:364:143295.
Rafati A, et al. Using vitamin E to prevent the impairment in behavioral test, cell loss and dendrite changes in medial prefrontal cortex induced by tartrazine in rats. Acta Histochem. 2017 Mar;119(2):172-180.
Miller MD, et al. Potential impacts of synthetic food dyes on activity and attention in children: a review of the human and animal evidence. Environ Health. 2022 Apr 29;21(1):45.
McCann D, et al. Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial. Lancet. 2007 Nov 3;370(9598):1560-7.
California Office of Environmental Health Hazard Assessment. “Health Effects Assessment: Potential Neurobehavioral Effects of Synthetic Food Dyes in Children”
Published Apr 16, 2021. https://oehha.ca.gov/risk-assessment/report/health-effects-assessment-potential-neurobehavioral-effects-synthetic-food
Miller, M.D., Steinmaus, C., Golub, M.S. et al. Potential impacts of synthetic food dyes on activity and attention in children: a review of the human and animal evidence. Environ Health 21, 45 (2022).
Nigg JT, Lewis K, Edinger T, Falk M. Meta-analysis of attention-deficit/hyperactivity disorder or attention-deficit/hyperactivity disorder symptoms, restriction diet, and synthetic food color additives. J Am Acad Child Adolesc Psychiatry. 2012 Jan;51(1):86-97.e8.
Rowe KS, Rowe KJ. Synthetic food coloring and behavior: a dose response effect in a double-blind, placebo-controlled, repeated-measures study. J Pediatr. 1994 Nov;125(5 Pt 1):691-8.
Soares BM et al. Effects on DNA repair in human lymphocytes exposed to the food dye tartrazine yellow. Anticancer Res. 2015 Mar;35(3):1465-74.
Zhang Q, et al. The synthetic food dye, Red 40, causes DNA damage, causes colonic inflammation, and impacts the microbiome in mice. Toxicol Rep. 2023 Sep 6;11:221-232.
Dipalma, JR. Tartrazine sensitivity. Am Fam Physician.1990 Nov;42(5):1347-50.
Stevenson, J, et al. The role of histamine degradation gene polymorphisms in moderating the effects of food additives on children’s ADHD symptoms. Am J Psychiatry. 2010 Sep;167(9):1108-15.

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It’s no surprise that goal setting is critical for success. Most people equate goals with career, work, and money. But goal setting can also be beneficial in other areas of your life too.
After 30-plus years of working with tens of thousands of patients, the psychiatrists at Amen Clinics routinely recommend a goal-setting tool called the One Page Miracle. This simple yet powerful tool makes a dramatic difference in the lives of those who practice it. It can be a game-changer in your life too.
The psychiatrists at Amen Clinics routinely recommend a goal-setting tool called the One Page Miracle. This simple yet powerful tool makes a dramatic difference in the lives of those who practice it.
To be happy and successful in life, we must identify our goals. Specifically, we need to know who we are and what we want to accomplish not only at work, but also in our relationships, our physical and mental health, and spirituality.
When we know what we want in each of these areas of our lives, we are more likely to change our behavior to get it. With our lives guided by our goals, we are more inclined to make decisions that serve us.
Goal setting begins in the brain. Neuroscience research proves it. Setting goals involves planning, attention, impulse control, working memory, and other processes collectively known as executive functions. These functions are largely regulated by the brain’s prefrontal cortex.
The prefrontal cortex (PFC) is located behind the forehead, and it plays a major role in decision-making. When the PFC is healthy, it acts like a brake in the brain to prevent you from unhelpful behaviors. For example, it’s what helps you say no to an extramarital affair, a third helping of cake, or a fourth round of cocktails.
If the PFC is underactive, however, it makes you more impulsive and can prevent you from reaching your primary goals. It makes you more likely to say yes to things that don’t serve you.
Goal setting effectively rewires the brain and boosts activity in the PFC. Creating a goal-setting worksheet essentially gives you an “auxiliary prefrontal cortex.” It will reinforce your conscious mind.
When Amen Clinics patients first hear about the importance of goal setting in life, they often respond with blank stares, say something related to career or financial goals, or talk about a dream vacation.
However, goal setting is not just for financial objectives or for some far-off dream. It is for the present, and it is critical for your daily actions. Identifying goals that you can focus on every day will have a major impact on your life.
Research shows that when setting goals, it’s best to focus on what you want, not what you don’t want. When you choose goals that guide you toward desirable outcomes, psychiatrists and psychologists call them approach goals. On the other hand, avoidance goals drive you away from undesirable outcomes.
An approach goal might be: “I’m going to take a brisk walk in the afternoon after work.”
An avoidant goal might be: “I’m going to stop going to the bar after work.”
Although these goals may seem similar, they activate different emotional and cognitive processes in the brain. Approach goals are linked to greater positivity and healthier mental well-being. Avoidant goals are associated with more negativity.
Because of this, approach goals are more beneficial in helping people achieve their objectives. For this reason, be sure to focus on the positive changes you want to make rather than the bad habits you want to eliminate.
In goal-setting, include mastery goals that will help you achieve your performance goals. Mastery goals involve boosting your abilities by learning new skills. Performance goals involve setting benchmarks that judge your abilities.
For example, a performance goal might be: “I’m going to lose 15 pounds by the end of this month.”
A mastery goal might be: “I’m going to learn how to prepare healthy foods at home.”
Although these are both approach goals that move you toward a desirable outcome, they aren’t the same. Failing to achieve the goal to drop 15 pounds might make you feel like weight loss is impossible for you. It can be a demotivator that prevents you from trying to reach your goal.
When you set a performance goal, include one of more mastery goals that will help you reach that objective.
When engaging in the goal-setting process, be sure to include 4 key aspects of life: relationships, work, money, and self. By addressing what you want in each of these areas, you are more likely to achieve a more balanced life.
You are more vulnerable to burnout when your life becomes unbalanced, or when you focus too intently on a single aspect of life at the expense of others. By focusing on all of the key areas of life, you can make sure that your life stays in balance.
The physicians at Amen Clinics typically ask patients do a goal-setting exercise called the One-Page Miracle (OPM). The One Page Miracle will help direct your actions, thoughts, and words. It can quickly bring clarity to your life and can rapidly create a positive impact.
The steps to create your own One Page Miracle are simple. On a single sheet of paper, simply write (or type) these four category headings and subcategories:
Next to each subcategory on your goal-setting worksheet, write down what you want in that area. As mentioned above, be sure to describe what you want, not what you want to avoid.
Write in the first person, using “I want…” to begin each section. Keep a positive tone throughout. Carry your One Page Miracle with you for a few days so you can refine your goals.
Once you have completed a first draft, put this sheet of paper somewhere you can see it each day. For example, you might want to tape it to your bathroom mirror, use a magnet to attach it to your refrigerator, or put it in your briefcase. With it in plain view, you can stay focused on your life’s primary objectives.
On a daily basis, ask yourself, “Is my behavior today getting me what I want?” Doing so will help you focus your behavior and actions on the things that matter most to you. It also helps you develop greater self-control, which is key to better decision-making.
Overall, you will live a more conscious, intentional, purposeful life. You will expend your energy on things that bring joy and happiness to you. Ultimately, this will make your life far more fulfilling.
If you’d like a more in-depth guide to the One Page Miracle, tune in to the Change Your Brain Every Day podcast. In this helpful episode, Dr. Amen and Tana Amen walk you through the process using their own goals as examples.
American Psychiatric Association, American Adults Express Increasing Anxiousness in Annual Poll; Stress and Sleep are Key Factors Impacting Mental Health, https://www.psychiatry.org/news-room/news-releases/annual-poll-adults-express-increasing-anxiousness
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Discover the surprising habit superagers—older people with rock solid memory function—all have in common.

Discover the fibermaxxing trend and how fiber helps the gut microbiome, which benefits brain health, digestion, mood, and overall wellness.
America is an unhappy nation, with depression rates escalating to records levels. Many depressed people turn to pharmaceuticals for what they think is an easy solution to their feelings of emptiness, sadness, and hopelessness.
That’s why rates of antidepressant prescriptions are on the rise. According to a 2024 study in JAMA Network Open, the number of antidepressant prescriptions jumped 21% from 2019 to 2022. And a greater percentage of these scripts were written via telehealth, skyrocketing from only 1.5% in 2019 to over 31% in 2022.
The problem with this is that antidepressants come with a laundry list of side effects, including sexual dysfunction, insomnia, headaches, and nausea. They also carry a black box warning, meaning they pose the most serious and dangerous potential side effects, such as suicidal thoughts. In addition, once you start taking certain types of antidepressants, it can be very hard to stop.
The good news is, there are many effective alternatives to antidepressants to consider. In this blog, you’ll learn more about clinical depression, antidepressant medications, and 11 proven strategies to try before turning to medication.
Antidepressants come with a laundry list of side effects, including sexual dysfunction, insomnia, headaches, and nausea. The good news is, there are many effective alternatives to antidepressants to consider.
Major Depressive Disorder (MDD) is a serious mental health condition that affects millions of people worldwide. Characterized by persistent feelings of sadness, hopelessness, and a lack of interest in activities that once brought joy, MDD can significantly impair daily life.
This condition can stem from a complex interplay of genetic, environmental, and psychological factors, often triggered by stressful life events, trauma, or underlying medical conditions.
Common depression symptoms include:
Diagnosing clinical depression involves a comprehensive evaluation by a mental health professional, which includes a physical exam, medical history, and psychological assessment.
Treatment typically involves a combination of medication, therapy, and lifestyle changes, tailored to the individual’s needs. Understanding MDD is the first step towards effective depression treatment and improving overall mental health.
There are several types of prescription antidepressants, which are believed to work by altering brain chemistry. Some of the most commonly prescribed antidepressants include:
Beyond traditional treatments, several alternative therapies have shown promise in managing depression symptoms. These therapies can be particularly beneficial for those seeking holistic approaches to mental health.
At Amen Clinics, the world’s leader in brain health and mental wellness, the specialists typically assess each patient’s biological risk factors. These are known as the 11 BRIGHT MINDS risk factors that steal your mind and can increase mental illness, including depression and anxiety. BRIGHT MINDS stands for:
To learn more about how to prevent, treat, or minimize your risk factors to help soothe depression and other mental health issues, watch this video. You’ll discover how the BRIGHT MINDS risk factors impact depression and other mental health symptoms, and what you can do about them.
Hypothyroidism is a very common cause of depression. Be aware that most traditional medical professionals only check for “normal” levels of thyroid, but some people may have normal test results but have symptoms. It’s better to test for “optimal” levels.
Whenever you have a thought, your brain releases chemicals. Whenever you have an angry, hopeless, helpless, or worthless thought, your brain releases chemicals that make you feel bad. On the flip side, hopeful, helpful, loving, happy thoughts release chemicals that make you feel good.
If you focus on what you hate about your life, you’ll hate it. Focus on what you love about your life, and you will love your life.
To kill the ANTs, learn to question your negative thoughts. Whenever you have a thought that makes you feel sad, ask yourself if it is true. Chances are, it isn’t.
This simple technique is similar to mindfulness-based cognitive therapy (MBCT). Combining mindfulness techniques with cognitive-behavioral therapy, MBCT helps individuals manage negative thoughts and behaviors, promoting a more balanced mental state.
This innovative therapy uses eye movements or other forms of stimulation to process and integrate traumatic memories, reducing symptoms of post-traumatic stress disorder (PTSD) and depression.
In a head-to-head study against Zoloft, exercise was equally effective in treating depression at 12 weeks. At 10 months, exercise was more effective than antidepressant medication.
To get the antidepressant benefits of exercise, walk like you’re late for 45 minutes 4-5 times a week. In addition, do weight training twice a week as it can increase testosterone, which improves mood, memory, and motivation. Do some kind of coordination exercise, such as table tennis, to work your cerebellum, which activates the rest of your brain.
Getting a good sweat from taking saunas has been shown to help reduce symptoms associated with depression.
Your diet has a major impact on your moods. Increase your consumption of foods that boost moods and decrease your intake of foods that contribute to depressive symptoms.
For example, eat high-quality protein, complex carbohydrates, and lots of colorful vegetables. A 2016 study showed a linear correlation between the number of fruits and veggies in your diet and your level of happiness. The more fruits and veggies (up to eight servings per day), the happier you will be.
On the flip side, eliminate processed foods, fried foods, and high-glycemic foods. To determine if specific foods are contributing to your depression, try an elimination diet.
Eliminate sugar; gluten; dairy; corn; soy; artificial dyes, preservatives, and sweeteners; and other potentially allergenic foods from your diet for three weeks. Then add each one back one at a time (except for sugar, which you should eliminate for good) and take note of any reactions to them, which would indicate that you should permanently eliminate that food.
Some people say they can’t afford to eat well, but how much is your depression costing you? A study from the Harvard School of Public Health found that eating well can cost just an extra $1.50 a day. That’s less than the cost of one session with most psychiatrists.
Combining mindfulness techniques with stress reduction strategies, MBSR helps individuals manage stress and anxiety, contributing to improved mental health.
MBSR may include yoga and meditation. These mind-body practices incorporate physical postures, breathing techniques, and meditation to reduce stress and anxiety, fostering relaxation and mental clarity.
A 2022 systematic review of 22 trials involving 2,391 participants found that acupuncture has clinical benefits and is a safe alternative for managing depression. Rooted in traditional Chinese medicine, acupuncture involves inserting thin needles into specific points on the body to stimulate healing and relaxation, potentially alleviating depression symptoms.
Transcranial magnetic stimulation (TMS) is a non-invasive treatment that uses magnetic pulses to stimulate nerve cells in the brain, showing effectiveness in treating depression, particularly for those who haven’t responded to other treatments.
You can’t change what you don’t measure. Having abnormal levels of these certain vitamins and nutrients has been linked to symptoms of depression. For example, having low levels of omega-3 fatty acids, folate, vitamin B12, vitamin D, and homocysteine have been associated with depressive symptoms.
Approximately 93% of the population has sub-optimal levels of omega-3 fatty acids. The Omega-3 Index is a blood test that measures your omega-3 level. Try to get it above 8% by using 1,000mg-3,000mg of omega-3 fish oil. EPA has been found effective for depression, so be sure to choose a high-quality fish oil that is rich in EPA to help treat depression.
To boost methylfolate, vitamin B12 and vitamin D levels, take a high-quality supplement.
Work with a nutritionally informed physician, such as a functional medicine physician (also known as an integrative medicine physician), to check and optimize your nutrient levels.
Other natural supplements have A-level or B-level scientific evidence for mood and can be used to treat severe depression. What does that mean? A-level means there is robust research conducted with more than 2 placebo-controlled, double-blind clinical trials. B-level means there are multiple studies where at least 2 are placebo-controlled, double-blind studies. Among these well-studied supplements for mood are:
Exploring these alternative therapies for depression can provide additional tools for managing depression and enhancing overall mental health.
In recent years, psychedelics have emerged as alternatives to antidepressants and have gained attention. Although some believe they offer new hope for individuals struggling with treatment-resistant depression, they come with potentially dangerous side effects and may harm the brain in the long-term.
Before resorting to these antidepressant alternatives, it’s important to understand the pros and cons of psychedelics for depression.
Effectively managing depression symptoms can often involve alternatives to antidepressants, such as therapy, lifestyle changes, and natural remedies, which offer holistic paths to recovery. Here are some strategies to help manage depressive symptoms and improve mental health:
By incorporating these strategies into daily life, individuals can better manage their depression symptoms and work towards improved mental health and well-being.
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Financial stress is a feeling many of us are, unfortunately, all too familiar with in today’s ever-changing economy. Whether you’re worrying about how to pay your bills, dealing with unexpected expenses, or managing debt, the weight of financial anxiety can feel overwhelming.
It’s not even just a matter of stress. These kinds of money worries can deeply impact your cognitive function. In fact, financial stress doesn’t just drain your energy—it can actually affect your brain’s ability to solve problems and plan effectively.
Understanding how financial pressure impacts your brain health and decision-making ability is the first step to overcoming money problems and mental health issues. Then you can take practical steps to improve your financial wellbeing and mental health.
Understanding how financial pressure impacts your brain health and decision-making ability is the first step to overcoming money problems and mental health issues.
Your brain’s executive center is essentially its control center, so it’s responsible for organizing, planning, and making decisions. This includes processes like memory, attention, problem-solving, and impulse control.
When your executive functions are compromised, tasks that require focus or long-term planning can become difficult. Think of the last time you had brain fog and anxiety at a time you needed to concentrate. Nothing gets done and everything feels impossible to accomplish.
When your brain is under stress—especially financial stress—your cognitive abilities are impaired, you get stuck on making any decisions, managing resources seems impossible, and mental clarity gets cloudy. It can be torturous when you’re just trying to get through the work day or mentally relax but you still have a million things to do.
Your executive center plays a huge role in how you navigate daily challenges and make thoughtful choices, so taking care of your brain under financial stress is critical.
In a nutshell, financial stress is the mental, emotional, and psychological strain caused by financial difficulties. This can come from a variety of factors, such as:
The constant worry about making ends meet or achieving your financial goals can become all-consuming, which only leads to a heightened state of anxiety. This type of stress triggers your body’s fight-or-flight response, which releases stress hormones like cortisol, ultimately affecting your brain’s ability to function efficiently.
When faced with money worries, the brain enters a heightened state of stress, which directly impacts cognitive function. According to research, financial scarcity can narrow your cognitive “bandwidth tax” and leave you with fewer mental resources to devote to everyday tasks.
This affects your ability to weigh the pros and cons of deciding what’s best for your financial situation, also known as “tunneling”. This means that, when your mind is consumed by financial worry, it can be harder to focus on other important things like your job, your relationships, and your physical health.
Stress-related decision-making mistakes happen when you’re worrying about money, bills, and debt. A 2018 study conducted by the American Academy of Neurology found stress hormones, like cortisol, interfere with memory and cognitive function, which can actually make your brain volume shrink. Money worries can exacerbate those conditions since money is a necessary part of survival today.
Financial pressure often leads to rash decisions, such as impulse spending or avoidance of critical financial tasks. Anxiety impairs self-control because you’re more likely to try and alleviate stress by choosing short-term relief that results in long-term financial instability.
For example, people experiencing financial anxiety may resort to high-interest loans or credit card debt, ultimately compounding their stress instead of alleviating it. Some of this can be necessary to alleviate the immediate burden, but it’s still important to gain financial literacy to improve the situation sooner rather than later.
Chronic stress alters brain structure, particularly in the prefrontal cortex, which is responsible for decision-making, impulse control, and managing complex tasks. The more stressed you are, the more difficult it becomes to take a step back and evaluate your financial situation rationally.
This can lead to a vicious cycle where stress-induced poor decisions, like overspending or delaying critical payments, further exacerbate financial strain. Over time, these repeated stress responses weaken your prefrontal cortex and make it even harder to break free from those reactive patterns.
Financial anxiety can directly interfere with your cognitive function by overwhelming your brain with constant worry. A Pew Research study found that people who experience significant financial anxiety have higher levels of cortisol that are often associated with several adverse health outcomes, such as:
Financial stress can also lead to increased activity in the amygdala, the brain region responsible for processing emotions like fear and anxiety. Chronic financial hardship has been associated with reduced amygdala volume, potentially impacting emotional regulation and increasing susceptibility to stress-related disorders.
Financial strain has been shown to reduce gray matter in areas of the brain responsible for memory and learning, especially when growing up in poverty. This increases the likelihood of errors and cognitive biases that impact future financial health and health outcomes.
Essentially, the brain’s executive function becomes compromised, affecting everything from day-to-day decisions to long-term financial planning.
Scientific evidence shows that stress also reduces neuroplasticity—your brain’s ability to adapt and change—but all hope is not lost. For example, chronic financial stress often makes it harder for the brain to form new habits, learn new skills, or adapt to changing financial circumstances. As a result, under financial pressure, you may struggle to develop healthier financial habits or better ways of managing your money.
Making thoughtful decisions when you’re under financial stress isn’t easy, but it’s not impossible. To help you make better financial decisions, start by breaking down larger financial goals into smaller, more manageable steps. This can reduce the overwhelming feeling that often follows financial pressures—no matter the size.
Additionally, mindfulness practices like meditation or breathing exercises can help calm the mind, enabling clearer thinking and better decision-making before you dive into your budget. Taking breaks and stepping away from whatever is causing you financial worry can also help reduce your stress levels to improve your ability to make sound choices.
While it’s nearly impossible to eliminate financial stress completely, there are coping strategies that can reduce the severity of its impact on your brain health and mental well-being. Here are some tips that may help:
Creating a realistic budget and sticking to it can help alleviate financial anxiety by offering clarity and control over your finances.
If you can swing it, financial advisors and counselors can offer practical advice and guidance to reduce anxiety and improve future decisions.
Regular activity can alleviate physical symptoms, reduce stress, improve cognitive blood flow, and maintain mental clarity during financial challenges.
Focus on ways to start building an emergency fund to reduce the fear of unexpected expenses and alleviate financial burdens.
Practicing stress management can improve emotional regulation and strengthen resilience, which can keep you calm and help you focus on what you can do right now.
The relationship between financial stress and brain health is complex but undeniable. Money worries can diminish mental clarity, impair decision-making, and affect overall brain function.
However, by implementing stress-reduction strategies, seeking professional advice, and focusing on improving financial health and literacy, it is possible to regain control and reduce the cognitive impacts of financial pressure.
Remember, managing your financial health not only improves your bank account but also strengthens your mind, enabling you to make clearer, more thoughtful decisions, both financially and in other aspects of life.
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Taking care of your mental health can often fall to the wayside when you’re busy juggling other seemingly more pertinent things. But, just like a regular physical checkup, a mental health checkup is essential for staying emotionally and mentally fit.
According to 2022 Mental Health America stats, nearly 25% of Americans—roughly 60 million adults—experienced a mental illness in the past year. However, research found only about 50.6% of that number, which is about 30 million people, received a diagnosis and treatment for their mental illness.
Whether you’re curious about your own mental well-being or looking out for loved ones, a mental health check-in can help you catch early signs of mental health symptoms.
In this blog, we’ll go over a few starting points to assess any signs of mental health conditions so you can take action if necessary. If any of these 10 areas raise a concern, please don’t hesitate to consult with a mental healthcare professional for more in-depth mental health screening.
Whether you're curious about your own mental well-being or looking out for loved ones, a mental health check-in can help you catch early signs of mental health symptoms.
Difficulty concentrating is often one of the first signs of mental health decline. According to the National Institute of Mental Health, cognitive issues, like trouble focusing or memory lapses, are common symptoms of mental disorders such as depression and anxiety.
When your brain struggles to manage emotional imbalances or hormonal changes, your ability to process information and stay attentive can rapidly decline. If you find yourself repeatedly rereading the same paragraph or zoning out during conversations, it’s time for a mental health check-in.
Sleep is one of your most crucial needs to sustain life and plays a significant role in sustaining your physical well-being and mental health. Research shows that people who experience poor sleep and insomnia are 10 times more likely to develop mental health conditions like depression.
Your brain needs sleep to detoxify, process emotions, and restore itself. This is why you feel refreshed when you get quality REM sleep for seven or more hours consistently. This also affects your recovery time for any fitness goals, healing ability for your skin and gut health, and immune response for your ability to fight off illnesses.
If you’re consistently waking up tired or struggling with insomnia, this is a red flag for potential mental illness.
Procrastination and avoidance can feel like familiar habits to lean into, but they may signal underlying mental health disorders if left unchecked. Avoidance coping can quickly turn into chronic avoidance, which can lead to heightened stress and exacerbate mental health symptoms.
Ignoring responsibilities or isolating yourself from others only compounds feelings of anxiety or depression.
The real question becomes: Are you avoiding tasks or interactions because they feel overwhelming or because you need a break?
Pay attention to how your mind and body feel when you’re procrastinating and make a self-care plan to address what is causing you to avoid a task or situation.
Understanding the mind-body connection is vital for maintaining good mental health and building your self-awareness. Being self-aware means recognizing how your thoughts and emotions affect your physical and mental health.
Making habits of mindful practices like meditation have been shown to help improve self-awareness and reduce signs of mental health decline. In fact, a 2023 study found that prioritizing self-awareness as a mental health practice can help you develop the ability to introspect their emotions and establish necessary positive and negative cognitive functions.
Regular self-reflection will help you identify triggers and manage emotional responses more effectively. The focus should be on learning more about who you are within your mind and body to know what you need to feel and live better.
Sudden mood swings, such as increased irritability or apathy, often indicates oncoming mental health issues. The World Health Organization (WHO) notes that mood disorders, including bipolar disorder and depression, affect over 280 million people globally.
Some mood changes can become more severe signs of mental health issues like:
If you find yourself snapping at loved ones or feeling indifferent about things you once enjoyed, it’s time for a mental health assessment.
A noticeable drop in energy levels, despite adequate sleep and nutrition, could signal mental health symptoms. According to Harvard Health, chronic fatigue often accompanies many mental health conditions like depression, anxiety, bipolar disorder, post-traumatic stress disorder (PTSD), generalized anxiety disorder (GAD), and more.
If you’re struggling to find the energy for daily activities or socializing, it’s important to find a healthcare professional to get your important health numbers checked as well.
Anxiety and depression are two of the most common mental health conditions in the U.S., affecting tens of millions each year. These mental disorders can significantly impact your quality of life if left untreated. That’s why it’s essential to recognize the signs as early as possible.
Signs of Anxiety:
Signs of Depression:
A healthy social life doesn’t mean you need a large group of friends, but it does involve maintaining connections and seeking out new experiences. Research shows that people with strong social ties have a 50% increased likelihood of longevity and better mental health.
That can be for a multitude of personal reasons; however, the overarching reasons have to do with the fact that we are social beings.
The focus of your interactions should be about positive reinforcement, shared experiences, emotional support, and a sense of belonging. Just keep in mind, if you find yourself withdrawing from social interactions, it could be a sign of mental health decline.
Finding balance between work and personal life is key to maintaining mental well-being. Research from the American Psychological Association highlights that job satisfaction and self-esteem are closely linked to mental health conditions.
Reflect on whether your current lifestyle supports your goals, values, and self-care routines. Writing in a journal can be helpful to track whether you feel accomplished or are experiencing burnout.
Focus on how you feel now and where you want to be in the future to take more concrete steps in your mental health checkup plan.
Mental health doesn’t just affect your thoughts—it can also manifest physically. Common signs of mental health problems can often include:
According to the Mayo Clinic, physical symptoms like these often accompany high stress, excessive anxiety, and chronic depression. Pay attention to what your body might be telling you about your mental state to know if you should see a mental health professional for screening.
Just as routine physical exams help prevent illness, regular mental health check-ins can help you maintain emotional balance and prevent mental illness from worsening. Statistics from the National Alliance on Mental Illness (NAMI) reveal that 1 in 5 U.S. adults experience mental health disorders each year, but early intervention can significantly improve health outcomes.
By addressing mental health symptoms early, you can enhance your quality of life and reduce the risk of developing more severe mental health conditions.
Mental Health America. (2024). Prevalence of Mental Illness 2024. Mental Health America. https://mhanational.org/issues/2024/mental-health-america-prevalence-data
Substance Abuse and Mental Health Services Administration. (2023). Key substance use and mental health indicators in the United States: Results from the 2022 National Survey on Drug Use and Health (HHS Publication No. PEP23-07-01-006, NSDUH Series H-58). Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. www.samhsa.gov/data/report/2022-nsduh-annual-national-report
National Institute of Mental Health (NIMH). (2024). Depression. National Institute of Mental Health. www.nimh.nih.gov/health/publications/depression
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Yeo G, Tan C, Ho D, Baumeister RF. How do aspects of selfhood relate to depression and anxiety among youth? A meta-analysis. Psychol Med. 2023 Aug;53(11):4833-4855. doi: 10.1017/S0033291723001083. Epub 2023 May 22. PMID: 37212050; PMCID: PMC10476091.
Mechlińska A, Wiglusz MS, Słupski J, Włodarczyk A, Cubała WJ. Exploring the Relationship between Mood Disorders and Coexisting Health Conditions: The Focus on Nutraceuticals. Brain Sci. 2023 Aug 30;13(9):1262. doi: 10.3390/brainsci13091262. PMID: 37759862; PMCID: PMC10526332.
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National Alliance on Mental Illness (NAMI). (2023, April). Mental Health By the Numbers. www.nami.org/about-mental-illness/mental-health-by-the-numbers/

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